Incest is human sexual activity between family members or close relatives. This typically includes sexual activity between people in consanguinity, and sometimes those related by affinity, adoption, or lineage. It is strictly forbidden and considered immoral in most societies, and can lead to an increased risk of genetic disorders in children.
Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. By analogy, the term is used in human reproduction, but more commonly refers to the genetic disorders and other consequences that may arise from expression of deleterious recessive traits resulting from incestuous sexual relationships and consanguinity. Animals avoid incest only rarely.
An incest taboo is any cultural rule or norm that prohibits sexual relations between certain members of the same family, mainly between individuals related by blood. All human cultures have norms that exclude certain close relatives from those considered suitable or permissible sexual or marriage partners, making such relationships taboo. However, different norms exist among cultures as to which blood relations are permissible as sexual partners and which are not. Sexual relations between related persons which are subject to the taboo are called incestuous relationships.
Exogamy is the social norm of mating or marrying outside one's social group. The group defines the scope and extent of exogamy, and the rules and enforcement mechanisms that ensure its continuity. One form of exogamy is dual exogamy, in which two groups continually intermarry with each other.
Endogamy is the cultural practice of mating—usually in the form of marriage—within a specific social group, religious denomination, caste, or ethnic group, rejecting those from others as unsuitable for marriage or other close interpersonal relationships. Whereas endogamy refers to marriage within the group, its opposite, exogamy, describes the social norm of marriage outside of the group.
Consanguinity is the characteristic of having a kinship with a relative who is descended from a common ancestor.
The coefficient of relationship is a measure of the degree of consanguinity between two individuals. The term coefficient of relationship was defined by Sewall Wright in 1922, and was derived from his definition of the coefficient of inbreeding of 1921. The measure is most commonly used in genetics and genealogy. A coefficient of inbreeding can be calculated for an individual, and is typically one-half the coefficient of relationship between the parents.
In genealogy, pedigree collapse describes how reproduction between two individuals who share an ancestor causes the number of distinct ancestors in the family tree of their offspring to be smaller than it could otherwise be. Robert C. Gunderson coined the term; synonyms include implex and the German Ahnenschwund.
A cousin is a relative that is the child of a parent's sibling. Cousins have a familial relationship by sharing a blood ancestor. Degrees and removals are separate measures used to more precisely describe the relationship between cousins. Degree measures the separation, in generations, from the most recent common ancestor(s) to a parent of one of the cousins, while removal measures the difference in generations between the cousins themselves, relative to their most recent common ancestor(s). To illustrate usage, a secondcousin is a cousin with a degree of two; there are three generations from the common ancestor(s). When the degree is not specified, first cousin is assumed. A cousin "once removed" is a cousin with one removal. When the removal is not specified, no removal is assumed.
Genetic load is the difference between the fitness of an average genotype in a population and the fitness of some reference genotype, which may be either the best present in a population, or may be the theoretically optimal genotype. The average individual taken from a population with a low genetic load will generally, when grown in the same conditions, have more surviving offspring than the average individual from a population with a high genetic load. Genetic load can also be seen as reduced fitness at the population level compared to what the population would have if all individuals had the reference high-fitness genotype. High genetic load may put a population in danger of extinction.
Inbreeding depression is the reduced biological fitness which has the potential to result from inbreeding. Biological fitness refers to an organism's ability to survive and perpetuate its genetic material. Inbreeding depression is often the result of a population bottleneck. In general, the higher the genetic variation or gene pool within a breeding population, the less likely it is to suffer from inbreeding depression, though inbreeding and outbreeding depression can simultaneously occur.
In law and in cultural anthropology, affinity is the kinship relationship created or that exists between two people as a result of someone's marriage. It is the relationship which each party to a marriage has to the relations of the other partner to the marriage, but it does not cover the marital relationship itself. Laws, traditions and customs relating to affinity vary considerably, sometimes ceasing with the death of one of the marriage partners through whom affinity is traced, and sometimes with the divorce of the marriage partners. In addition to kinship by marriage, "affinity" can sometimes also include kinship by adoption or a step relationship.
Fumarase deficiency is an exceedingly rare autosomal recessive metabolic disorder in the Krebs cycle, characterized by a deficiency of the enzyme fumarate hydratase, which causes a buildup of fumaric acid in the urine and a deficiency of malate. Only 13 cases were known worldwide in 1990, after which a cluster of 20 cases was documented in a community in Arizona that has practiced successive endogamy.
A cousin marriage is a marriage where the spouses are cousins. The practice was common in earlier times and continues to be common in some societies today, though in some jurisdictions such marriages are prohibited. Worldwide, more than 10% of marriages are between first or second cousins. Cousin marriage is an important topic in anthropology and alliance theory.
Out-crossing or out-breeding is the technique of crossing between different breeds. This is the practice of introducing distantly related genetic material into a breeding line, thereby increasing genetic diversity.
Reproductive compensation was originally a theory to explain why recessive genetic disorders may persist in a population. It was proposed in 1967 as an explanation for the maintenance of Rh negative blood groups. Reproductive compensation refers to the tendency of parents, seeking a given family size, to replace offspring that are lost to genetic disorders. It may also refer to the effects of increased maternal or parental investment in caring for disadvantaged offspring, seeking to compensate for genetic disadvantage. It is a theory that suggests that behavioral as well as physiological factors may play a role in the level of recessive genetic disorders in a population.
The medical genetics of Jews have been studied to identify and prevent some rare genetic diseases that, while still rare, are more common than average among people of Jewish descent. There are several autosomal recessive genetic disorders that are more common than average in ethnically Jewish populations, particularly Ashkenazi Jews, because of relatively recent population bottlenecks and because of consanguineous marriage. These two phenomena reduce genetic diversity and raise the chance that two parents will carry a mutation in the same gene and pass on both mutations to a child.
Cousin marriage, a form of consanguinity. As of 2003, an average of 45% of married couples were related in the Arab world. While consanguinity is not unique to the Arab or Islamic world, Arab countries have had "some of the highest rates of consanguineous marriages in the world". The bint 'amm marriage, or marriage with one's father's brother's daughter is especially common, especially in tribal and traditional Muslim communities, where men and women seldom meet potential spouses outside the extended family.
Inbreeding avoidance, or the inbreeding avoidance hypothesis, is a concept in evolutionary biology that refers to the prevention of the deleterious effects of inbreeding. Animals only rarely exhibit inbreeding avoidance. The inbreeding avoidance hypothesis posits that certain mechanisms develop within a species, or within a given population of a species, as a result of assortative mating and natural and sexual selection, in order to prevent breeding among related individuals. Although inbreeding may impose certain evolutionary costs, inbreeding avoidance, which limits the number of potential mates for a given individual, can inflict opportunity costs. Therefore, a balance exists between inbreeding and inbreeding avoidance. This balance determines whether inbreeding mechanisms develop and the specific nature of such mechanisms.
Achalasia microcephaly syndrome is a rare condition whereby achalasia in the oesophagus manifests alongside microcephaly and mental retardation. This is a rare constellation of symptoms with a predicted familial trend.
![Cognitive abilities among inbred and non-inbred children in "families of five Muslim populations of [the] Jammu region." Cognitive abilities among inbred and non-inbred children.png](http://upload.wikimedia.org/wikipedia/commons/thumb/2/23/Cognitive_abilities_among_inbred_and_non-inbred_children.png/230px-Cognitive_abilities_among_inbred_and_non-inbred_children.png)
