Copper gluconate

Last updated
Copper gluconate
Copper gluconate.png
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a601072
Routes of
administration
Oral
ATC code
Identifiers
  • Copper(II) gluconate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard 100.007.645 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C12H22CuO14
Molar mass 453.840 g·mol−1
3D model (JSmol)
Melting point 156 °C (313 °F)
Solubility in water 30 mg/mL (20 °C)
  • C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Cu+2]
  • InChI=1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1 X mark.svgN
  • Key:OCUCCJIRFHNWBP-IYEMJOQQSA-L X mark.svgN
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Copper gluconate is the copper salt of D-gluconic acid. It is an odorless, light blue or blue-green crystal or powder which is easily soluble in water and insoluble in ethanol. [1] [2]

Contents

Uses

Side effects

The U.S. Institute of Medicine (IOM) sets tolerable upper intake levels (ULs) for vitamins and minerals when evidence is sufficient. In the case of copper the adult UL is set at 10 mg/day. [4]

Copper gluconate is sold as a dietary supplement to provide copper. The typical dose is 2.0 mg copper per day. This is one-fifth what the IOM considers a safe upper limit. Long-term intake at amounts higher than the UL may cause liver damage. [4]

References

  1. "产品列表-葡萄糖酸铜" [Product list - copper gluconate]. Liaoyang Tengyuan Food Additives Factory. Archived from the original on April 2, 2015. Retrieved March 29, 2013.(in Chinese)
  2. "Copper Gluconate". ChemicalLand21. Retrieved March 29, 2013.
  3. Sawyer DT (1964). "Metal-Gluconate Complexes". Chemical Reviews. 64 (6): 633–643. doi:10.1021/cr60232a003.
  4. 1 2 Food and Nutrition Board, Institute of Medicine (2001). "Chapter 9: Copper". DRI: dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc : a report of the Panel on Micronutrients ... and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Washington, D.C.: National Academy Press. pp. 224–257. ISBN   978-0-309-07290-8.