Cyclopentanol dehydrogenase

Last updated
cyclopentanol dehydrogenase
Identifiers
EC no. 1.1.1.163
CAS no. 37364-12-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, cyclopentanol dehydrogenase (EC 1.1.1.163) is an enzyme that catalyzes the chemical reaction

+ NAD+
 
 
 
H+
Cyclopentanol dehydrogenase
 
H+
 
+ NADH
 

The two substrates of this enzyme are cyclopentanol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are cyclopentanone, reduced NADH, and a proton. [1] [2] [3]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cyclopentanol:NAD+ oxidoreductase.

References

  1. Enzyme 1.1.1.163 at KEGG Pathway Database.
  2. Griffin M, Trudgill PW (1972). "The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872". Biochem. J. 129 (3): 595–603. doi:10.1042/bj1290595. PMC   1174162 . PMID   4349113.
  3. Iwaki H, Hasegawa Y, Wang S, Kayser MM, Lau PC (2002). "Cloning and characterization of a gene cluster involved in cyclopentanol metabolism in Comamonas sp. strain NCIMB 9872 and biotransformations effected by Escherichia coli-expressed cyclopentanone 1,2-monooxygenase". Appl. Environ. Microbiol. 68 (11): 5671–84. Bibcode:2002ApEnM..68.5671I. doi:10.1128/AEM.68.11.5671-5684.2002. PMC   129933 . PMID   12406764.