Dammarenediol II synthase

Dammarenediol II synthase
Identifiers
EC no.	4.2.1.125
CAS no.	189354-84-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Dammarenediol II synthase (EC 4.2.1.125, dammarenediol synthase, 2,3-oxidosqualene (20S)-dammarenediol cyclase, DDS, (S)-squalene-2,3-epoxide hydro-lyase (dammarenediol-II forming)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (dammarenediol-II forming). ^{[1] [2]} This enzyme catalyses the following chemical reaction

dammarenediol II ${\displaystyle \rightleftharpoons }$ (3S)-2,3-epoxy-2,3-dihydrosqualene + H₂O

The reaction occurs in the reverse direction.

References

1. Tansakul P, Shibuya M, Kushiro T, Ebizuka Y (October 2006). "Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng". FEBS Letters. 580 (22): 5143–9. doi:10.1016/j.febslet.2006.08.044. PMID   16962103.
2. Han JY, Kwon YS, Yang DC, Jung YR, Choi YE (December 2006). "Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng". Plant & Cell Physiology. 47 (12): 1653–62. doi: 10.1093/pcp/pcl032 . PMID   17088293.

External links

• Dammarenediol+II+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)