Endomysium | |
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Identifiers | |
TA98 | A04.0.00.043 |
TA2 | 2007 |
TH | H3.03.00.0.00004 |
FMA | 9729 |
Anatomical terminology |
The endomysium, meaning within the muscle, is a wispy layer of areolar connective tissue that ensheaths each individual muscle fiber, or muscle cell. [1] [2] [3] It also contains capillaries and nerves. It overlies the muscle fiber's cell membrane: the sarcolemma. Endomysium is the deepest and smallest component of muscle connective tissue. This thin layer helps provide an appropriate chemical environment for the exchange of calcium, sodium, and potassium, which is essential for the excitation and subsequent contraction of a muscle fiber.
Endomysium combines with perimysium and epimysium to create the collagen fibers of tendons, providing the tissue connection between muscles and bones by indirect attachment. [4] It connects with perimysium using intermittent perimysial junction plates. [5]
Collagen is the major protein that composes connective tissues like endomysium. [6] Endomysium has been shown to contain mainly type I and type III collagen components, and type IV and type V in very minor amounts. [7] Others have found type IV and type V more common. [2]
The term cardiac skeleton is sometimes considered synonymous with endomysium in the heart, but cardiac skeleton also refers to the combination of the endomysium and perimysium.
Anti-endomysial antibodies (EMA) are present in celiac disease. [8] They do not cause any direct symptoms to muscles, but detection of EMA is useful in the diagnosis of the disease. [9]
Striated muscle tissue is a muscle tissue that features repeating functional units called sarcomeres. The presence of sarcomeres manifests as a series of bands visible along the muscle fibers, which is responsible for the striated appearance observed in microscopic images of this tissue. There are two types of striated muscle:
Pectoralis minor muscle is a thin, triangular muscle, situated at the upper part of the chest, beneath the pectoralis major in the human body. It arises from ribs III-V; it inserts onto the coracoid process of the scapula. It is innervated by the medial pectoral nerve. Its function is to stabilise the scapula by holding it fast in position against the chest wall.
The quadriceps femoris muscle is a large muscle group that includes the four prevailing muscles on the front of the thigh. It is the sole extensor muscle of the knee, forming a large fleshy mass which covers the front and sides of the femur. The name derives from Latin four-headed muscle of the femur.
Perimysium is a sheath of dense irregular connective tissue that groups muscle fibers into bundles or fascicles.
Epimysium is the fibrous tissue envelope that surrounds muscle. It is a layer of dense irregular connective tissue which ensheaths the entire muscle and protects muscles from friction against other muscles and bones. It also allows a muscle to contract and move powerfully while maintaining its structural integrity.
The epineurium is the outermost layer of dense irregular connective tissue surrounding a peripheral nerve. It usually surrounds multiple nerve fascicles as well as blood vessels which supply the nerve. Smaller branches of these blood vessels penetrate into the perineurium. In addition to blood vessels which supply the nerve, lymphocytes and fibroblasts are also present and contribute to the production of collagen fibers that form the backbone of the epineurium. In addition to providing structural support, lymphocytes and fibroblasts also play a vital role in maintenance and repair of the surrounding tissues.
Intrafusal muscle fibers are skeletal muscle fibers that serve as specialized sensory organs (proprioceptors). They detect the amount and rate of change in length of a muscle. They constitute the muscle spindle, and are innervated by both sensory (afferent) and motor (efferent) fibers.
The coronal suture is a dense, fibrous connective tissue joint that separates the two parietal bones from the frontal bone of the skull.
Deep fascia is a fascia, a layer of dense connective tissue that can surround individual muscles and groups of muscles to separate into fascial compartments.
Ground substance is an amorphous gel-like substance in the extracellular space of animals that contains all components of the extracellular matrix (ECM) except for fibrous materials such as collagen and elastin. Ground substance is active in the development, movement, and proliferation of tissues, as well as their metabolism. Additionally, cells use it for support, water storage, binding, and a medium for intercellular exchange. Ground substance provides lubrication for collagen fibers.
The gluteal tuberosity is the lateral one of the three upward prolongations of the linea aspera of the femur, extending to the base of the greater trochanter. It serves as the principal insertion site for the gluteus maximus muscle.
The lateral sacral arteries is an artery in the pelvis that arises from the posterior division of the internal iliac artery. It later splits into two smaller branches, a superior and an inferior.
The adductor canal is an aponeurotic tunnel in the middle third of the thigh giving passage to parts of the femoral artery, vein, and nerve. It extends from the apex of the femoral triangle to the adductor hiatus.
The medial pterygoid nerve (nerve to medial pterygoid, or internal pterygoid nerve) is a nerve of the head. It is a branch of the mandibular nerve (CN V3). It supplies the medial pterygoid muscle, the tensor veli palatini muscle, and the tensor tympani muscle.
The common extensor tendon is a tendon that attaches to the lateral epicondyle of the humerus.
A muscle fascicle is a bundle of skeletal muscle fibers surrounded by perimysium, a type of connective tissue.
The endoneurium is a layer of delicate connective tissue around the myelin sheath of each myelinated nerve fiber in the peripheral nervous system. Its component cells are called endoneurial cells. The endoneuria with their enclosed nerve fibers are bundled into groups called nerve fascicles, each fascicle within its own protective sheath called a perineurium. In sufficiently large nerves multiple fascicles, each with its blood supply and fatty tissue, may be bundled within yet another sheath, the epineurium.
The obturator canal is a passageway formed in the obturator foramen by part of the obturator membrane and the pelvis. It connects the pelvis to the thigh.
The buccopharyngeal fascia is a fascia of the pharynx. It represents the posterior portion of the pretracheal fascia. It covers the superior pharyngeal constrictor muscles, and buccinator muscle.
A key component in lateral force transmission in skeletal muscle is the extracellular matrix (ECM). Skeletal muscle is a complex biological material that is composed of muscle fibers and an ECM consisting of the epimysium, perimysium, and endomysium. It can be described as a collagen fiber-reinforced composite. The ECM has at least three functions: (1) to provide a framework binding muscle fibers together and ensure their proper alignment, (2) to transmit the forces, either from active muscle contraction or ones passively imposed on it, and (3) providing lubricated surfaces between muscle fibers and bundles enabling the muscle to change shape. The mechanical properties of skeletal muscle depend on both the properties of muscle fibers and the ECM, and the interaction between the two. Contractile forces are transmitted laterally within intramuscular connective tissue to the epimysium and then to the tendon. Due to the nature of skeletal muscle, direct measurements are not possible, but many indirect studies and analyses have shown that the ECM is an important part of force transmission during muscle contraction.