Epi-isozizaene synthase

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epi-isozizaene synthase
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EC no. 4.2.3.37
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epi-Isozizaene synthase (EC 4.2.3.37, SCO5222 protein) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-epi-isozizaene-forming). [1] [2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-epi-isozizaene + diphosphate

This enzyme requires Mg2+ for activity.

Related Research Articles

The enzyme aristolochene synthase catalyzes the chemical reaction

The enzyme pentalenene synthase catalyzes the chemical reaction

Epi-isozizaene 5-monooxygenase (EC 1.14.13.106, CYP170A1) is an enzyme with systematic name (+)-epi-isozizaene,NADPH:oxygen oxidoreductase (5-hydroxylating). This enzyme catalyses the following chemical reaction

<span class="mw-page-title-main">Geosmin synthase</span>

Geosmin synthase or germacradienol-geosmin synthase designates a class of bifunctional enzymes that catalyze the conversion of farnesyl diphosphate (FPP) to geosmin, a volatile organic compound known for its earthy smell. The N-terminal half of the protein catalyzes the conversion of farnesyl diphosphate to germacradienol and germacrene D, followed by the C-terminal-mediated conversion of germacradienol to geosmin. The conversion of FPP to geosmin was previously thought to involve multiple enzymes in a biosynthetic pathway.

Germacradienol synthase (EC 4.2.3.22, germacradienol/germacrene-D synthase, 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming]) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming). This enzyme catalyses the following chemical reaction

epi-Cedrol synthase (EC 4.2.3.39, 8-epicedrol synthase, epicedrol synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming). This enzyme catalyses the following chemical reaction

β-Farnesene synthase (EC 4.2.3.47, farnesene synthase, terpene synthase 10, terpene synthase 10-B73, TPS10) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-β-farnesene-forming). This enzyme catalyses the following chemical reaction

5-Epiaristolochene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ( -5-epiaristolochene-forming). This enzyme catalyses the following chemical reaction

(+)-α-Barbatene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ( -α-barbatene-forming). This enzyme catalyses the following chemical reaction

Valencene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming). It is a terpene cyclase enzyme responsible for the biosynthesis of valencene, a sesquiterpene, using farnesyl pyrophosphate as its substrate. The first such enzyme was isolated using orange cDNA. This enzyme catalyses the following chemical reaction

Presilphiperfolanol synthase (EC 4.2.3.74, BcBOT2, CND15) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase (presilphiperfolan-8β-ol-forming). This enzyme catalyses the following chemical reaction

(–)-Germacrene D synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ( -germacrene-D-forming). This enzyme catalyses the following chemical reaction

7-epi-α-Selinene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (7-epi-α-selinene-forming). This enzyme catalyses the following chemical reaction

(+)-β-Caryophyllene synthase is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction:

5-epi-α-Selinene synthase is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

Avermitilol synthase (EC 4.2.3.96) is an enzyme with systematic name avermitilol hydrolase (cyclizing, avermitilol-forming). This enzyme catalyses the following chemical reaction

(–)-δ-Cadinene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

(+)-T-Muurolol synthase (EC 4.2.3.98) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-T-muurolol-forming). This enzyme catalyses the following chemical reaction

7-epi-Sesquithujene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (7-epi-sesquithujene-forming). This enzyme catalyses the following chemical reaction

(+)-Sativene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

References

  1. ↑ Lin X, Hopson R, Cane DE (May 2006). "Genome mining in Streptomyces coelicolor: molecular cloning and characterization of a new sesquiterpene synthase". Journal of the American Chemical Society. 128 (18): 6022–3. doi:10.1021/ja061292s. PMC   2533732 . PMID   16669656.
  2. ↑ Zhao B, Lin X, Lei L, Lamb DC, Kelly SL, Waterman MR, Cane DE (March 2008). "Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2)". The Journal of Biological Chemistry. 283 (13): 8183–9. doi: 10.1074/jbc.M710421200 . PMC   2276382 . PMID   18234666.


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