Erythroid dysplasia | |
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Specialty | Hematology |
Erythroid dysplasia is a condition in which immature red blood cells (erythroid cells) in the bone marrow are abnormal [1] in size and/or number. Erythroid dysplasia may be caused by vitamin deficiency or chemotherapy, or it may be a sign of refractory anemia, which is a myelodysplastic syndrome. Also called erythrodysplasia.[ citation needed ]
Acute myeloblastic leukemia without maturation is a quickly progressing disease in which too many immature white blood cells are found in the blood and bone marrow.
Anti-CD19 immunotoxin is a monoclonal antibody linked to a toxic substance. It is being studied in the treatment of some types of B-cell cancer. Anti-CD19 immunotoxin is made in the laboratory. It binds to CD19, a protein on the surface of normal B cells and B-cell tumors, and kills the cells.
An antigen-presenting cell vaccine, or an APC vaccine, is a vaccine made of antigens and antigen-presenting cells (APCs).
Atypical hyperplasia is a benign (noncancerous) cellular hyperplasia in which cells show some atypia. In this condition, cells look abnormal under a microscope and are increased in number.
Blastic phase chronic myelogenous leukemia is a phase of chronic myelogenous leukemia in which more than 30% of the cells in the blood or bone marrow are blast cells. When tiredness, fever, and an enlarged spleen occur during the blastic phase, it is called blast crisis.
A bone-seeking radioisotope is a radioactive substance that is given through a vein, and collects in bone cells and in tumor cells that have spread to the bone. It kills cancer cells by giving off low-level radiation.
A chemosensitivity assay is a laboratory test that measures the number of tumor cells that are killed by chemotherapy. The test is done after the tumor cells are removed from the body. A chemosensitivity assay may help in choosing the best drug or drugs for the cancer being treated.
An autologous tumor cell is a cancer cell from an individual's own tumor.
Thymic carcinoma is a rare type of thymus gland cancer. It usually spreads, has a high risk of recurrence, and has a poor survival rate. Thymic carcinoma is divided into subtypes, depending on the types of cells in which the cancer began. Also called type C thymoma.
Chronic phase chronic myelogenous leukemia is a phase of chronic myelogenous leukemia in which 5% or fewer of the cells in the blood and bone marrow are blast cells. This phase may last from several months to several years, and there may be no symptoms of leukemia.
Gliosarcoma is a rare type of glioma, a cancer of the brain that comes from glial, or supportive, brain cells, as opposed to the neural brain cells. Gliosarcoma is a malignant cancer, and is defined as a glioblastoma consisting of gliomatous and sarcomatous components.
Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover internal organs and that contains long spindle-shaped cells. It is also called sarcomatoid carcinoma.
Syngeneic stem cell transplantation is a procedure in which a patient receives blood-forming stem cells donated by his or her healthy identical twin.
Molecular risk assessment is a procedure in which biomarkers are used to estimate a person's risk for developing cancer. Specific biomarkers may be linked to particular types of cancer.
Precursor T-lymphoblastic lymphoma is a type of non-Hodgkin lymphoma in which too many T-cell lymphoblasts are found in the lymph nodes and spleen. Also called T-lymphoblastic lymphoma, it is most common in young men.
An exocrine pancreas cell is a pancreatic cell that produces enzymes that are secreted into the small intestine. These enzymes help digest food by releasing enzymes as it passes through the gastrointestinal tract. These include acinar cells, which secrete bicarbonate solution and mucin.
Segmental resection is a surgical procedure to remove part of an organ or gland, as a sub-type of a resection, which might involve removing the whole body part. It may also be used to remove a tumor and normal tissue around it. In lung cancer surgery, segmental resection refers to removing a section of a lobe of the lung. The resection margin is the edge of the removed tissue; it is important that this shows free of cancerous cells on examination by a pathologist.
Microwave thermotherapy, is a type of treatment in which body tissue is heated by microwave irradiation to damage and kill cancer cells or to make cancer cells more sensitive to the effects of radiation and certain anticancer drugs.
Signal transduction inhibitors are drugs that may prevent the ability of cancer cells to multiply quickly and invade other tissues.
Tumor progression is the third and last phase in tumor development. This phase is characterised by increased growth speed and invasiveness of the tumor cells. As a result of the progression, phenotypical changes occur and the tumor becomes more aggressive and acquires greater malignant potential. Together with the progression, more and more aneuploidy occurs. This may be evident as nuclear polymorphism.
This article incorporates public domain material from the U.S. National Cancer Institute document: "Dictionary of Cancer Terms".