Names | |
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IUPAC name 3,5,7-Trihydroxyflavone | |
Systematic IUPAC name 3,5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one | |
Other names Norizalpinin 3,5,7-triOH-Flavone | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.008.147 |
KEGG | |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C15H10O5 | |
Molar mass | 270.240 g·mol−1 |
Density | 1.579 g/mL |
Melting point | 214 to 215 °C (417 to 419 °F; 487 to 488 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Galangin is found in high concentrations in plants like Alpinia officinarum (lesser galangal) [1] and Helichrysum aureonitens . [2] It is also found in the rhizome of Alpinia galanga [3] and in propolis. [4]
Galangin has been shown to have in vitro antibacterial [5] [6] [7] and antiviral activity. [8] It also inhibits the growth of breast tumor cells in vitro . [9] [10]
Chelerythrine is a benzophenanthridine alkaloid present in the plant Chelidonium majus. It is a potent, selective, and cell-permeable protein kinase C inhibitor in vitro. And an efficacious antagonist of G-protein-coupled CB1 receptors. This molecule also exhibits anticancer qualities and it has served as a base for many potential novel drugs against cancer. Structurally, this molecule has two distinct conformations, one being a positively charged iminium form, and the other being an uncharged form, a pseudo-base.
Alpinia officinarum, known as lesser galangal, is a plant in the ginger family, cultivated in Southeast Asia. It originated in China, where its name ultimately derives. It can grow 1.5 to 2 m high, with long leaves and reddish-white flowers. The rhizomes, known as galangal, are valued for their sweet spicy flavor and aromatic scent. These are used throughout Asia in curries and perfumes, and were previously used widely in Europe. They are also used as a herbal remedy.
Kaempferia galanga, commonly known as kencur, aromatic ginger, sand ginger, cutcherry, is a monocotyledonous plant in the ginger family, and one of four plants called galangal. It is found primarily in open areas in Indonesia, southern China, Taiwan, Cambodia, and India, but is also widely cultivated throughout Southeast Asia.
Pycnoporus sanguineus is a white rot saprobic fungus. It was discovered on Guana Island but occurs throughout the tropics and subtropics, usually growing on dead hardwoods. It grows in the form of a thin dry conk with a lateral attachment to its substrate, or sometimes a very short stipe. The cap is orange-red to orange, lightening to salmon/buff in age. It has concentric zonation, and is finely tomentose to nearly glabrous. The pores on the underside are round, measuring 5-6 per mm with tubes up to 2mm deep. It is inedible due to its tough texture.
Tamarixetin is an O-methylated flavonol, a naturally occurring flavonoid. It has been isolated from Tamarix ramosissima.
Taxifolin (5,7,3',4'-flavan-on-ol), also known as dihydroquercetin, belongs to the subclass flavanonols in the flavonoids, which in turn is a class of polyphenols. It is extracted from plants such as Siberian larch and milk thistle.
Hyperoside is a chemical compound. It is the 3-O-galactoside of quercetin.
Epicatechin gallate (ECG) is a flavan-3-ol, a type of flavonoid, present in green tea. It is also reported in buckwheat and in grape.
Prenylated flavonoids or prenylflavonoids are a sub-class of flavonoids. They are widely distributed throughout the plant kingdom. Some are known to have phytoestrogenic or antioxidant properties. They are given in the list of adaptogens in herbalism. Chemically they have a prenyl group attached to their flavonoid backbone. It is usually assumed that the addition of hydrophobic prenyl groups facilitate attachment to cell membranes. Prenylation may increase the potential activity of its original flavonoid.
Artemisia herba-alba, the white wormwood, is a perennial shrub in the genus Artemisia that grows commonly on the dry steppes of the Mediterranean regions in Northern Africa, Western Asia and Southwestern Europe. It is used as an antiseptic and antispasmodic in herbal medicine.
Rhein, also known as cassic acid, is a substance in the anthraquinone group obtained from rhubarb. Like all such substances, rhein is a cathartic, which is commonly found as a glycoside such as rhein-8-glucoside or glucorhein. Rhein was first isolated in 1895. It is found in rhubarb species like Rheum undulatum and Rheum palmatum as well as in Cassia reticulata.
Rhus chinensis, the Chinese sumac or nutgall tree, is a deciduous shrub or small tree in the genus Rhus. Growing to 6 m (20 ft) tall, it has downy shoots and leaves comprising several leaflets. These turn red in autumn before falling.
Verbascoside is a polyphenol glycoside in which the phenylpropanoid caffeic acid and the phenylethanoid hydroxytyrosol form an ester and an ether bond respectively, to the rhamnose part of a disaccharide, namely β-(3′,4′-dihydroxyphenyl)ethyl-O-α-L-rhamnopyranosyl(1→3)-β-D-(4-O-caffeoyl)-glucopyranoside.
Bakuchiol is a meroterpenoid in the class terpenophenol.
Dorstenia mannii is a plant species in the genus Dorstenia.
Kuwanon G is an antimicrobial bombesin receptor antagonist isolated from white mulberry.
Dianethole is a naturally occurring organic compound that is found in anise and fennel. It is a dimeric polymer of anethole. It has estrogenic activity, and along with anethole and photoanethole, may be responsible for the estrogenic effects of anise and fennel. These compounds bear resemblance to the estrogens stilbene and diethylstilbestrol, which may explain their estrogenic activity. In fact, it is said that diethylstilbestrol and related drugs were originally modeled after dianethole and photoanethole.
Photoanethole is a naturally occurring organic compound that is found in anise and fennel. It has estrogenic activity, and along with anethole and dianethole, may be responsible for the estrogenic effects of anise and fennel. These compounds bear resemblance to the estrogens stilbene and diethylstilbestrol, which may explain their estrogenic activity. In fact, it is said that diethylstilbestrol and related drugs were originally modeled after photoanethole and dianethole.
Cassandra Leah Quave is an American ethnobotanist, herbarium curator, and associate professor at Emory University. Her research focuses on analyzing natural, plant-based medicine of indigenous cultures to help combat infectious disease and antibiotic resistance. In particular, she studies bacterial biofilm inhibition and quorum-sensing inhibition of botanical extracts for inflammatory skin conditions.
Begonia malabarica, the Malabar begonia, is a species of flowering plant in the family Begoniaceae, native to India and Sri Lanka. It has antibacterial properties.