Glucose-6-phosphate dehydrogenase (coenzyme-F420)

Glucose-6-phosphate dehydrogenase (coenzyme-F420)
Identifiers
EC no.	1.1.98.2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Glucose-6-phosphate dehydrogenase (coenzyme-F420) (EC 1.1.98.2, coenzyme F420-dependent glucose-6-phosphate dehydrogenase, F420-dependent glucose-6-phosphate dehydrogenase, FGD1, Rv0407, F420-dependent glucose-6-phosphate dehydrogenase 1) is an enzyme with systematic name D-glucose-6-phosphate:F420 1-oxidoreductase. ^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

D-glucose 6-phosphate + oxidized coenzyme F420 ${\displaystyle \rightleftharpoons }$ 6-phospho-D-glucono-1,5-lactone + reduced coenzyme F420

Thus enzyme is specific for D-glucose 6-phosphate.

References

1. Purwantini E, Daniels L (May 1996). "Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis". Journal of Bacteriology. 178 (10): 2861–6. doi:10.1128/jb.178.10.2861-2866.1996. PMC   178021 . PMID   8631674.
2. Bashiri G, Squire CJ, Baker EN, Moreland NJ (July 2007). "Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system". Protein Expression and Purification. 54 (1): 38–44. doi:10.1016/j.pep.2007.01.014. PMID   17376702.
3. Purwantini E, Gillis TP, Daniels L (January 1997). "Presence of F420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea". FEMS Microbiology Letters. 146 (1): 129–34. doi: 10.1111/j.1574-6968.1997.tb10182.x . PMID   8997717.

External links

• Glucose-6-phosphate+dehydrogenase+(coenzyme-F420) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)