Glycerol-3-phosphate oxidase

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glycerol-3-phosphate oxidase
Identifiers
EC no. 1.1.3.21
CAS no. 9046-28-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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NCBI proteins

In enzymology, glycerol-3-phosphate oxidase (EC 1.1.3.21) is an enzyme that catalyzes the chemical reaction

 
O2
H2O2
Glycerol-3-phosphate oxidase
O2
H2O2
 

The two substrates of this enzyme are sn-glycerol 3-phosphate and oxygen. Its products are dihydroxyacetone phosphate and hydrogen peroxide. [1] [2] [3]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is sn-glycerol-3-phosphate:oxygen 2-oxidoreductase. Other names in common use include glycerol phosphate oxidase, glycerol-1-phosphate oxidase, glycerol phosphate oxidase, L-alpha-glycerophosphate oxidase, alpha-glycerophosphate oxidase, and L-alpha-glycerol-3-phosphate oxidase. This enzyme participates in glycerophospholipid metabolism. It employs one cofactor, FAD.

References

  1. Enzyme 1.1.3.21 at KEGG Pathway Database.
  2. Gancedo C, Gancedo JM, Sols A (1968). "Glycerol metabolism in yeasts. Pathways of utilization and production". Eur. J. Biochem. 5 (2): 165–72. doi: 10.1111/j.1432-1033.1968.tb00353.x . PMID   5667352.
  3. Koditschek LK, Umbreit WW (1969). "Alpha-glycerophosphate oxidase in Streptococcus faecium F 24". J. Bacteriol. 98 (3): 1063–8. doi:10.1128/jb.98.3.1063-1068.1969. PMC   315296 . PMID   5788698.