Hyalobarrier

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Hyalobarrier is a substance to keep tissue apart post surgery and therefore prevent adhesions. It contains autocross-linked hyaluronan. Highly viscous due to condensation. Hyaluronan is present in cartilage and skin hence there is a natural metabolic pathway for it. This gel is used to separate organs and tissue after surgery. Scientific documentation so far covers the gynaecology speciality. IE Laparoscopic surgery, hysteroscopy/hysteroscopic surgery but also open surgery. According to data in a Cochrane collaboration review barrier agents may be a little more effective in preventing adhesions than no intervention. The Cochrane report also states that the incidence of postsurgical adhesions is as high as 50 to 100%. [1] In a recent review by C Sutton (University of Surrey, Guilford UK), it is stated that Hyalobarrier is the only anti adhesive substance that has published data for intrauterine use. [2]

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References

  1. Ahmad, Gaity; Kim, Kyungmin; Thompson, Matthew; Agarwal, Priya; O'Flynn, Helena; Hindocha, Akshay; Watson, Andrew (March 22, 2020). "Barrier agents for adhesion prevention after gynaecological surgery". The Cochrane Database of Systematic Reviews. 3 (3): CD000475. doi:10.1002/14651858.CD000475.pub4. ISSN   1469-493X. PMC   7085418 . PMID   32199406.
  2. Sutton C (2009). "Adhesions following surgery: pathogenesis and current experience with adhesion barriers". Surg Technol Int. 18: 144–56. PMID   19579202.