Hydroxymalonate dehydrogenase

Last updated
hydroxymalonate dehydrogenase
Identifiers
EC no. 1.1.1.167
CAS no. 58693-60-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a hydroxymalonate dehydrogenase (EC 1.1.1.167) is an enzyme that catalyzes the chemical reaction

+ NAD+
 
 
 
H+
Hydroxymalonate dehydrogenase
 
H+
 
+ NADH
 

The two substrates of this enzyme are tartronic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are mesoxalic acid, reduced NADH, and a proton. [1] [2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hydroxymalonate:NAD+ oxidoreductase.

References

  1. Enzyme 1.1.1.167 at KEGG Pathway Database.
  2. Jukova NI, Klunova SM, Philippovich YB (1971). Biochemistry of Insects (17). Moscow: V.I. Lenin State Pedagogical Institute: 56.{{cite journal}}: Missing or empty |title= (help)