Ioglicic acid

Ioglicic acid

Clinical data
ATC code	V08AA06 ( WHO )
Identifiers
IUPAC name 3-acetamido-2,4,6-triiodo-5-{[(methylcarbamoyl)methyl]carbamoyl}benzoic acid
CAS Number	49755-67-1
PubChem CID	65437
DrugBank	DB13701
ChemSpider	58900
UNII	3LGR5S8101
KEGG	D04574
ChEMBL	ChEMBL1201291
CompTox Dashboard (EPA)	DTXSID10198023
ECHA InfoCard	100.051.320
Chemical and physical data
Formula	C13H12I3N3O5
Molar mass	670.968 g·mol−1
3D model (JSmol)	Interactive image
SMILES Ic1c(c(I)c(c(I)c1NC(=O)C)C(=O)O)C(=O)NCC(=O)NC

Ioglicic acid is a pharmaceutical drug that was used as an iodinated contrast medium for X-ray imaging, in form of its salt meglumine ioglicate. Uses included imaging of the brain, ^[1] the aorta and femoral arteries, ^[2] and the urinary system (an examination called intravenous urography). ^[3]

It is not known to be marketed anywhere in the world in 2021.

References

1. Skalpe IO (1983). "Enhancement with water-soluble contrast media in computed tomography of the brain and abdomen. Survey and present state". Acta Radiologica. Supplementum. 366: 72–5. PMID   6382938.
2. Wiebe V, Straub H (1983). "Haemodynamic side effects of meglumine ioglicate, meglumine sodium ioxaglate and iohexol in aortofemoral angiography: comparison of a high-osmolar and two low-osmolar radiological contrast media". Fortschritte Auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband. 118: 78–84. PMID   6139084.
3. Baitsch T, Beduhn D, Klink G (1983). "Double blind comparison of ioglicate and iothalamate in intravenous urography". Fortschritte Auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband. 118: 143–7. PMID   6139069.