Iopromide

Last updated
Iopromide
Iopromide.png
Clinical data
Trade names Ultravist
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pregnancy
category
  • AU:B2
Routes of
administration 		Intravascular
ATC code
Legal status
Legal status
Pharmacokinetic data
Protein binding ~1%
Metabolism None
Elimination half-life 2 hours
Excretion Kidneys
Identifiers
  • 1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-1-N-methylbenzene-1,3-dicarboxamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.070.330 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C18H24I3N3O8
Molar mass 791.116 g·mol−1
3D model (JSmol)
  • CN(CC(CO)O)C(=O)c1c(c(c(c(c1I)NC(=O)COC)I)C(=O)NCC(CO)O)I
  • InChI=1S/C18H24I3N3O8/c1-24(4-9(28)6-26)18(31)12-13(19)11(17(30)22-3-8(27)5-25)14(20)16(15(12)21)23-10(29)7-32-2/h8-9,25-28H,3-7H2,1-2H3,(H,22,30)(H,23,29) X mark.svgN
  • Key:DGAIEPBNLOQYER-UHFFFAOYSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Iopromide is an iodinated contrast medium for X-ray imaging. It is marketed under the name Ultravist which is produced by Bayer Healthcare. It is a low osmolar, non-ionic contrast agent for intravascular use; i.e., it is injected into blood vessels. [1]

Contents

It is commonly used in radiographic studies such as intravenous urograms, brain computer tomography (CT) [1] and CT pulmonary angiograms (CTPAs).

Medical uses

The radiocontrast agent is given intravenously in computed tomography (CT) scans, angiography and excretory urography. [2]

Contraindications

Iopromide use is contraindicated in myelography, cerebral ventriculography and cisternography procedures. It is also contraindicated in those with hyperthyroidism, or with known allergy to the drug. [3]

Iopromide is also contraindicated in children with prolonged fasting, fluid restriction, on laxative, or dehydration as it can cause renal failure. [3]

References

  1. 1 2 Haberfeld H, ed. (2020). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Ultravist 300 mg J/ml-Infusionsflaschen.
  2. ↑ "Prescribing information - Ultravist" (PDF). Bayer Healthcare pharmaceuticals. Archived from the original (PDF) on 10 April 2021.
  3. 1 2 "PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION ULTRAVIST® Iopromide Injection" (PDF). Bayer Healthcare Pharmaceuticals. Archived from the original (PDF) on 27 October 2021. Retrieved 16 April 2024.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.