Licodione synthase

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Licodione synthase
Identifiers
EC no. 1.14.13.87
CAS no. 157972-05-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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NCBI proteins

In enzymology, a licodione synthase (EC 1.14.13.87) is an enzyme that catalyzes the chemical reaction

liquiritigenin + NADPH + H+ + O2 licodione + NADP+ + H2O

The 4 substrates of this enzyme are liquiritigenin, NADPH, H+, and O2. Its 3 products are licodione, NADP+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom O oxygen into the other donor. The systematic name of this enzyme class is liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming).

References