Mevaldate reductase

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mevaldate reductase (NAD+)
Identifiers
EC no. 1.1.1.32
CAS no. 9028-33-5
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In enzymology, a mevaldate reductase (EC 1.1.1.32) is an enzyme that catalyzes the chemical reaction

(R)-mevalonate + NAD+ mevaldate + NADH + H+

Thus, the two substrates of this enzyme are (R)-mevalonate and NAD+, whereas its 3 products are mevaldate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-mevalonate:NAD+ oxidoreductase. This enzyme is also called mevalonic dehydrogenase.

In 2022, this entry was deleted from the Enzyme Classification, and is now included in with the entry for Alcohol dehydrogenase. [1]

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References

  1. "EC 1.1.1.32". ExplorEnz – the Enzyme Databas. International Union of Biochemistry and Molecular Biology (IUBMB). Deleted entry: mevaldate reductase, now included with EC 1.1.1.1, alcohol dehydrogenase.