Nicotine blue oxidoreductase

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Nicotine blue oxidoreductase
Identifiers
EC no. 1.1.1.328
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Nicotine blue oxidoreductase (EC 1.1.1.328, nboR (gene)) is an enzyme with systematic name 3,3'-bipyridine-2,2',5,5',6,6'-hexol:NADP+ 11-oxidoreductase. [1] This enzyme catalyses the following chemical reaction

3,3'-bipyridine-2,2',5,5',6,6'-hexol + NAD(P)+ (E)-2,2',5,5'-tetrahydroxy-6H,6'H-[3,3'-bipyridinylidene]-6,6'-dione + NAD(P)H + H+

This enzyme is extracted from bacterium Arthrobacter nicotinovorans .

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<span class="mw-page-title-main">BTBP</span> A class of tetradentate ligand compounds

The bis-triazinyl bipyridines (BTBPs) are a class of chemical compounds which are tetradentate ligands similar in shape to quaterpyridine. The BTBPs are made by the reaction of hydrazine and a 1,2-diketone with 6,6'-dicyano-2,2'-bipyridine. The dicyanobipy can be made by reacting 2,2'-bipy with hydrogen peroxide in acetic acid, to form 2,2'-bipyridine-N,N-dioxide. The 2,2'-bipyridine-N,N-dioxide is then converted into the dicyano compound by treatment with potassium cyanide and benzoyl chloride in a mixture of water and THF.

<span class="mw-page-title-main">2,6-Dihydroxypyridine</span> Chemical compound

2,6-Dihydroxypyridine is an alkaloid with the molecular formula C5H3N(OH)2. It is a colorless solid. 2,6-Dihyroxypyridine is an intermediate in the degradation of nicotine.

4-methylaminobutanoate oxidase (formaldehyde-forming) (EC 1.5.3.19, mabO (gene)) is an enzyme with systematic name 4-methylaminobutanoate:oxygen oxidoreductase (formaldehyde-forming). This enzyme catalyses the following chemical reaction

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6-hydroxypseudooxynicotine dehydrogenase (EC 1.5.99.14) is an enzyme with systematic name 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one:acceptor 6-oxidoreductase (hydroxylating). This enzyme catalyses the following chemical reaction:

2,6-dihydroxypseudooxynicotine hydrolase (EC 3.7.1.19) is an enzyme with systematic name 1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one hydrolase. This enzyme catalyses the following chemical reaction

<i>Paenarthrobacter nicotinovorans</i> Species of bacterium

Paenarthrobacter nicotinovorans is a Gram-positive and aerobic bacterium species from the genus Paenarthrobacter. This bacterium has the ability to degrade atrazine, nicotine, and creatine. and produces nicotine dehydrogenase

Transition metal complexes of 2,2'-bipyridine are coordination complexes containing one or more 2,2'-bipyridine ligands. Complexes have been described for all of the transition metals. Although few have any practical value, these complexes have been influential. 2,2'-Bipyridine is classified as a diimine ligand. Unlike the structures of pyridine complexes, the two rings in bipy are coplanar, which facilitates electron delocalization. As a consequence of this delocalization, bipy complexes often exhibit distinctive optical and redox properties.

References

  1. Mihasan M, Chiribau CB, Friedrich T, Artenie V, Brandsch R (April 2007). "An NAD(P)H-nicotine blue oxidoreductase is part of the nicotine regulon and may protect Arthrobacter nicotinovorans from oxidative stress during nicotine catabolism". Applied and Environmental Microbiology. 73 (8): 2479–85. doi:10.1128/AEM.02668-06. PMC   1855579 . PMID   17293530.