Phytoene desaturase (zeta-carotene-forming)

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Phytoene desaturase (zeta-carotene-forming)
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EC no. 1.3.99.29
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Phytoene desaturase (zeta-carotene-forming) (EC 1.3.99.29, CrtIa, 2-step phytoene desaturase (ambiguous), two-step phytoene desaturase (ambiguous)) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming). [1] This enzyme catalyses the following chemical reaction

Contents

15-cis-phytoene + 2 acceptor all-trans-zeta-carotene + 2 reduced acceptor (overall reaction)
(1a) 15-cis-phytoene + acceptor all-trans-phytofluene + reduced acceptor
(1b) all-trans-phytofluene + acceptor all-trans-zeta-carotene + reduced acceptor

The enzyme is involved in carotenoid biosynthesis.

See also

Related Research Articles

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Lycopene is an organic compound classified as a tetraterpene and a carotene. Lycopene is a bright red carotenoid hydrocarbon found in tomatoes and other red fruits and vegetables.

<span class="mw-page-title-main">Carotenoid</span> Class of chemical compounds; yellow, orange or red plant pigments

Carotenoids are yellow, orange, and red organic pigments that are produced by plants and algae, as well as several bacteria, archaea, and fungi. Carotenoids give the characteristic color to pumpkins, carrots, parsnips, corn, tomatoes, canaries, flamingos, salmon, lobster, shrimp, and daffodils. Over 1,100 identified carotenoids can be further categorized into two classes – xanthophylls and carotenes.

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In enzymology, a carotene 7,8-desaturase (EC 1.14.99.30) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Damascenone</span> Chemical compound

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<span class="mw-page-title-main">Phytoene</span> Chemical compound

Phytoene is a 40-carbon intermediate in the biosynthesis of carotenoids. The synthesis of phytoene is the first committed step in the synthesis of carotenoids in plants. Phytoene is produced from two molecules of geranylgeranyl pyrophosphate (GGPP) by the action of the enzyme phytoene synthase. The two GGPP molecules are condensed together followed by removal of diphosphate and proton shift leading to the formation of phytoene.

Phytoene synthase is a transferase enzyme involved in the biosynthesis of carotenoids. It catalyzes the conversion of geranylgeranyl pyrophosphate to phytoene. This enzyme catalyses the following chemical reaction

ζ-Carotene (zeta-carotene) is a carotenoid. It is different from α-carotene and β-carotene because it is acyclic. ζ-Carotene is similar in structure to lycopene, but has an additional 4 hydrogen atoms. ζ-carotene can be used as an intermediate in forming β-carotene. A dehydrogenation reaction converts ζ-carotene into lycopene, which then can be transformed into β-carotene through the action of lycopene beta-cyclase. ζ-Carotene is a natural product found in Lonicera japonica and Rhodospirillum rubrum.

<span class="mw-page-title-main">15-Cis-phytoene desaturase</span> Class of enzymes

15-cis-phytoene desaturases, are enzymes involved in the carotenoid biosynthesis in plants and cyanobacteria. Phytoene desaturases are membrane-bound enzymes localized in plastids and introduce two double bonds into their colorless substrate phytoene by dehydrogenation and isomerize two additional double bonds. This reaction starts a biochemical pathway involving three further enzymes called the poly-cis pathway and leads to the red colored lycopene. The homologous phytoene desaturase found in bacteria and fungi (CrtI) converts phytoene directly to lycopene by an all-trans pathway.

9,9'-dicis-zeta-carotene desaturase is an enzyme with systematic name 9,9'-dicis-zeta-corotene:quinone oxidoreductase. This enzyme catalyses the following chemical reaction

4,4'-Diapophytoene desaturase is an enzyme with systematic name 15-cis-4,4'-diapophytoene:FAD oxidoreductase. This enzyme catalyses the following chemical reaction

All-trans-zeta-carotene desaturase is an enzyme with systematic name all-trans-zeta-carotene:acceptor oxidoreductase. This enzyme catalyses the following chemical reaction

Phytoene desaturase (neurosporene-forming) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (neurosporene-forming). This enzyme catalyses the following chemical reaction

Phytoene desaturase (3,4-didehydrolycopene-forming) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming). This enzyme catalyses the following chemical reaction

<span class="mw-page-title-main">Phytoene desaturase (lycopene-forming)</span>

Phytoene desaturase (lycopene-forming) are enzymes found in archaea, bacteria and fungi that are involved in carotenoid biosynthesis. They catalyze the conversion of colorless 15-cis-phytoene into a bright red lycopene in a biochemical pathway called the poly-trans pathway. The same process in plants and cyanobacteria utilizes four separate enzymes in a poly-cis pathway.

All-trans-phytoene synthase is an enzyme with systematic name geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase . This enzyme catalyses the following chemical reaction

ζ-Carotene isomerase is an enzyme with systematic name 9,15,9'-tricis-zeta-carotene cis-trans-isomerase. This enzyme catalyses the following chemical reaction

Prolycopene isomerase is an enzyme with systematic name 7,9,7',9'-tetracis-lycopene cis-trans-isomerase. This enzyme catalyses the following chemical reaction

Beta-carotene isomerase is an enzyme with systematic name beta-carotene 9-cis-all-trans isomerase. This enzyme catalyses the following chemical reaction

Phytoene desaturase may refer to:

References

  1. Iniesta AA, Cervantes M, Murillo FJ (August 2007). "Cooperation of two carotene desaturases in the production of lycopene in Myxococcus xanthus". The FEBS Journal. 274 (16): 4306–14. doi: 10.1111/j.1742-4658.2007.05960.x . PMID   17662111.