Polythiazide

Last updated
Polythiazide
Polythiazide.svg
Polythiazide molecule spacefill.png
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a601101
ATC code
Identifiers
  • 6-chloro-2-methyl-3-{[(2,2,2-trifluoroethyl)thio]methyl}-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.005.881 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C11H13ClF3N3O4S3
Molar mass 439.87 g·mol−1
3D model (JSmol)
  • O=S(C1=CC(S(=O)(N(C(CSCC(F)(F)F)N2)C)=O)=C2C=C1Cl)(N)=O
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Polythiazide is a thiazide diuretic. [1] [2]

References

  1. O'Brien ET, MacKinnon J (October 1972). "Propranolol and polythiazide in treatment of hypertension". British Heart Journal. 34 (10): 1042–4. doi:10.1136/hrt.34.10.1042. PMC   458544 . PMID   5086971.
  2. Monroy A, Plata C, Hebert SC, Gamba G (July 2000). "Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction". American Journal of Physiology. Renal Physiology. 279 (1): F161-9. doi:10.1152/ajprenal.2000.279.1.f161. PMID   10894798.