Precorrin-2 dehydrogenase

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precorrin-2 dehydrogenase
Identifiers
EC no. 1.3.1.76
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In enzymology, a precorrin-2 dehydrogenase (EC 1.3.1.76) is an enzyme that catalyzes the chemical reaction

precorrin-2 + NAD+ sirohydrochlorin + NADH + H+
Precorrin-2 Dihydrosirochlorin.png
Precorrin-2
Sirohydrochlorin SirohydrochlorinCorr.png
Sirohydrochlorin

The two substrates of this enzyme are precorrin-2 and NAD+; its three products are sirohydrochlorin, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is precorrin-2:NAD+ oxidoreductase. Other names in common use include Met8p, SirC, and CysG. This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in anaerobic bacteria and to Cofactor F430.

See also

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References


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