Propanediol-phosphate dehydrogenase

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propanediol-phosphate dehydrogenase
Identifiers
EC no. 1.1.1.7
CAS no. 9028-15-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a propanediol-phosphate dehydrogenase (EC 1.1.1.7) is an enzyme that catalyzes the chemical reaction

Propanediol 1-phosphate.svg
Propanediol 1-phosphate
+ NAD+
 
 
 
H+
Biochem reaction arrow reversible NYYN horiz med.svg
 
H+
 
Hydroxacetone phosphate (neutral).svg
Hydroxyacetone phosphate
+ NADH
 

The two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD+. Its products are hydroxyacetone phosphate, nicotinamide adenine dinucleotide (NADH), and a proton. [1] [2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,2-diol-1-phosphate:NAD+ oxidoreductase. Other names in common use include PDP dehydrogenase, 1,2-propanediol-1-phosphate:NAD+ oxidoreductase, and propanediol phosphate dehydrogenase.

References

  1. Enzyme 1.1.1.7 at KEGG Pathway Database.
  2. Sellinger OZ, Miller ON (July 1959). "The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate dehydrogenase". The Journal of Biological Chemistry. 234 (7): 1641–6. doi: 10.1016/S0021-9258(18)69897-7 . PMID   13672935.