Valerena-4,7(11)-diene synthase

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Valerena-4,7(11)-diene synthase
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EC no. 4.2.3.139
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Valerena-4,7(11)-diene synthase (EC 4.2.3.139, VoTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, valerena-4,7(11)-diene-forming). [1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate valerena-4,7(11)-diene + diphosphate

This enzyme is isolated from the plant Valeriana officinalis (valerian).

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References

  1. Pyle BW, Tran HT, Pickel B, Haslam TM, Gao Z, MacNevin G, Vederas JC, Kim SU, Ro DK (September 2012). "Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis)". The FEBS Journal. 279 (17): 3136–46. doi:10.1111/j.1742-4658.2012.08692.x. PMID   22776156. S2CID   205885638.