Xanthoxin dehydrogenase

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Xanthoxin dehydrogenase
Identifiers
EC no. 1.1.1.288
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
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NCBI proteins

In enzymology, xanthoxin dehydrogenase (EC 1.1.1.288) is an enzyme that catalyzes the chemical reaction

+ NAD+
 
 
 
H+
Xanthoxin dehydrogenase
 
H+
 
+ NADH
 

The two substrates of this enzyme are xanthoxin and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are abscisic aldehyde, reduced NADH, and a proton. [1] [2] [3] [4]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is xanthoxin:NAD+ oxidoreductase. Other names in common use include xanthoxin oxidase, and ABA2. This enzyme participates in carotenoid biosynthesis.

References

  1. Enzyme 1.1.1.288 at KEGG Pathway Database.
  2. Sindhu RK; Walton DC (1988). "Xanthoxin metabolism in cell-free preparations from wild type and wilty mutants of tomato". Plant Physiol. 88 (1): 178–182. doi:10.1104/pp.88.1.178. PMC   1055545 . PMID   16666262.
  3. Schwartz SH, Leon-Kloosterziel KM, Koornneef M, Zeevaart JA (1997). "Biochemical characterization of the aba2 and aba3 mutants in Arabidopsis thaliana". Plant Physiol. 114 (1): 161–6. doi:10.1104/pp.114.1.161. PMC   158290 . PMID   9159947.
  4. Ponce MR, Micol JL, Serrano R, Rodriguez PL (2002). "The short-chain alcohol dehydrogenase ABA2 catalyzes the conversion of xanthoxin to abscisic aldehyde". Plant Cell. 14 (8): 1833–46. Bibcode:2002PlanC..14.1833G. doi:10.1105/tpc.002477. PMC   151468 . PMID   12172025.