GPR142

GPR142
Identifiers
Aliases	GPR142 , PGR2, G protein-coupled receptor 142, GPRg1b
External IDs	OMIM: 609046 MGI: 2668437 HomoloGene: 18770 GeneCards: GPR142
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,372,600 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	114,697,571 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; spleen; ; duodenum; ; lymph node; ; gastric mucosa; ; left uterine tube; ; right lobe of thyroid gland; ; appendix; ; canal of the cervix; ; fundus;
	Top expressed in
	islet of Langerhans; ; cochlea; ; pharynx; ; neck; ; habenula; ; peripheral nervous system; ; medial habenular nucleus; ; trigeminal ganglion; ; dentate gyrus; ; hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity ; signal transducer activity ;
Cellular component	integral component of membrane ; cell junction ; membrane ; plasma membrane ; cytosol ;
Biological process	G protein-coupled receptor signaling pathway ; signal transduction ;
	Sources:Amigo / QuickGO
Orthologs
	350383
	217302
	ENSG00000257008
	ENSMUSG00000034677
	Q7Z601
	Q7TQN9
	NM_181790 ; NM_001331076 ; NM_001331077
	NM_181749 ; NM_001346772 ; NM_001379097
	NP_001318005 ; NP_001318006 ; NP_861455
	NP_001333701 ; NP_861414 ; NP_001366026
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 09, 2023

Probable G-protein coupled receptor 142 is a protein that in humans is encoded by the GPR142 gene.^[5]^[6]

GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003).[supplied by OMIM]^[6]

Related Research Articles

Probable G-protein coupled receptor 20 is a protein that in humans is encoded by the GPR20 gene.

Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Probable G-protein coupled receptor 135 is a protein that in humans is encoded by the GPR135 gene.

Probable G-protein coupled receptor 123 is a protein that in humans is encoded by the GPR123 gene. It is a member of the adhesion-GPCR family of receptors. Family members are normally characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Probable G-protein coupled receptor 146 is a protein that in humans is encoded by the GPR146 gene. It has been identified as a possible receptor for C-peptide.

Adhesion G-protein coupled receptor A3 (ADGRA3), also known as GPR125, is an adhesion GPCR that in humans is encoded by the Adgra3 gene.

Probable G-protein coupled receptor 115 is a protein that in humans is encoded by the GPR115 gene.

Probable G-protein coupled receptor 111 is a protein that in humans is encoded by the GPR111 gene.

Probable G-protein coupled receptor 110 is a protein that in humans is encoded by the GPR110 gene. This gene encodes a member of the adhesion-GPCR receptor family. Family members are characterized by an extended extracellular region with a variable number of N-terminal protein modules coupled to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.

Probable G-protein coupled receptor 150 is a protein that in humans is encoded by the GPR150 gene.

Relaxin/insulin-like family peptide receptor 4, also known as RXFP4, is a human G-protein coupled receptor.

Probable G-protein coupled receptor 144 is a protein that in humans is encoded by the GPR144 gene. This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterised by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Probable G-protein coupled receptor 141 is a protein that in humans is encoded by the GPR141 gene.

Probable G-protein coupled receptor 153 is a protein that in humans is encoded by the GPR153 gene.

Probable G-protein coupled receptor 152 is a protein that in humans is encoded by the GPR152 gene.

Probable G-protein coupled receptor 162 is a protein that in humans is encoded by the GPR162 gene.

G-protein coupled receptor 139 (GPC139) is a protein that in humans is encoded by the GPR139 gene. Recent research ('21) has shown that mice with loss of GCP139 experience schizophrenia-like symptomatology that is rescued with the dopamine receptor antagonist haloperidol and the μ-opioid receptor antagonist naltrexone; as well, the recently developed, potent, and GPR139 receptor selective agonist TAK-041 is currently undergoing trials to gauge the efficacy for treating psychiatric conditions such as major depressive disorder and the negative symptoms of schizophrenia.

G protein-coupled receptor 148, also known as GPR148, is a human orphan receptor from GPCR superfamily. It is expressed primarily in nervous system and testis. Is may be implicated in prostate cancer.

Trace amine-associated receptor 9 is a protein that in humans is encoded by the TAAR9 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000257008 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034677 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB (Nov 2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Lett. 554 (3): 381–8. doi: 10.1016/S0014-5793(03)01196-7 . PMID 14623098. S2CID 11563502.
1 2 "Entrez Gene: GPR142 G protein-coupled receptor 142".

GPR142

Related Research Articles

References

Further reading