P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene. [3] [4]
P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene. [3] [4]
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [4]
Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma. [5]
The granulocyte colony-stimulating factor receptor (G-CSF-R) also known as CD114 is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. The granulocyte colony-stimulating factor receptor is present on precursor cells in the bone marrow, and, in response to stimulation by G-CSF, initiates cell proliferation and differentiation into mature neutrophilic granulocytes and macrophages.
Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. CD135 is the receptor for the cytokine Flt3 ligand (FLT3L).
B-cell lymphoma 6 protein is a protein that in humans is encoded by the BCL6 gene. Like BCL2, BCL3, BCL5, BCL7A, BCL9 and BCL10, it has clinical significance in lymphoma.
Beta-actin is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.
P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.
P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene.
C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene.
Lysophosphatidic acid receptor 4 also known as LPA4 is a protein that in humans is encoded by the LPAR4 gene. LPA4 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.i
P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.
Lysophosphatidic acid receptor 6, also known as LPA6, P2RY5 and GPR87, is a protein that in humans is encoded by the LPAR6 gene. LPA6 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.
P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.
The thrombopoietin receptor also known as the myeloproliferative leukemia protein or CD110 is a protein that in humans is encoded by the MPL oncogene.
Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily.
Protein BTG1 is a protein that in humans is encoded by the BTG1 gene.
B-cell lymphoma/leukemia 11A is a protein that in humans is encoded by the BCL11A gene.
P2X purinoceptor 5 is a protein that in humans is encoded by the P2RX5 gene.
Fc receptor-like protein 5 is a protein that in humans is encoded by the FCRL5 gene. FCRL5 has also been designated as CD307.
Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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