2-hydroxyisoflavanone dehydratase

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2-hydroxyisoflavanone dehydratase
Identifiers
EC no. 4.2.1.105
CAS no. 56022-25-4
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The enzyme 2-hydroxyisoflavanone dehydratase (EC 4.2.1.105) catalyzes the chemical reaction

2,7,4′-trihydroxyisoflavanone daidzein + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 2,7,4′-trihydroxyisoflavanone hydro-lyase (daidzein-forming). This enzyme is also called 2,7,4′-trihydroxyisoflavanone hydro-lyase. This enzyme participates in isoflavonoid biosynthesis.

The variant GmHID1 from Glycine max converts 2-hydroxyisoflavone to isoflavones, mostly daidzein and genistein. [1]

References

  1. Bauters, Lander; Lander Bauers; Stojilković, Boris; Gheysen, Godelieve (2021-08-19). "Pathogens pulling the strings: Effectors manipulating salicylic acid and phenylpropanoid biosynthesis in plants". Molecular Plant Pathology . 22 (11). British Society for Plant Pathology (Wiley): 1436–1448. Bibcode:2021MolPP..22.1436B. doi: 10.1111/mpp.13123 . ISSN   1464-6722. PMC   8518561 . PMID   34414650.