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This article is a summary of the 2020s in science and technology.
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Particle physics or high-energy physics is the study of fundamental particles and forces that constitute matter and radiation. The field also studies combinations of elementary particles up to the scale of protons and neutrons, while the study of combination of protons and neutrons is called nuclear physics.
The European Organization for Nuclear Research, known as CERN, is an intergovernmental organization that operates the largest particle physics laboratory in the world. Established in 1954, it is based in Meyrin, western suburb of Geneva, on the France–Switzerland border. It comprises 24 member states. Israel, admitted in 2013, is the only full member geographically out of Europe. CERN is an official United Nations General Assembly observer.
The Large Hadron Collider (LHC) is the world's largest and highest-energy particle accelerator. It was built by the European Organization for Nuclear Research (CERN) between 1998 and 2008 in collaboration with over 10,000 scientists and hundreds of universities and laboratories across more than 100 countries. It lies in a tunnel 27 kilometres (17 mi) in circumference and as deep as 175 metres (574 ft) beneath the France–Switzerland border near Geneva.
Maria Spiropulu is a Greek particle physicist. She is the Shang-Yi Ch'en Professor of Physics at the California Institute of Technology.
Quark–gluon plasma is an interacting localized assembly of quarks and gluons at thermal and chemical (abundance) equilibrium. The word plasma signals that free color charges are allowed. In a 1987 summary, Léon Van Hove pointed out the equivalence of the three terms: quark gluon plasma, quark matter and a new state of matter. Since the temperature is above the Hagedorn temperature—and thus above the scale of light u,d-quark mass—the pressure exhibits the relativistic Stefan-Boltzmann format governed by temperature to the fourth power and many practically massless quark and gluon constituents. It can be said that QGP emerges to be the new phase of strongly interacting matter which manifests its physical properties in terms of nearly free dynamics of practically massless gluons and quarks. Both quarks and gluons must be present in conditions near chemical (yield) equilibrium with their colour charge open for a new state of matter to be referred to as QGP.
This article is a summary of the 2010s in science and technology.
The Edison Volta Prize is awarded biennially by the European Physical Society (EPS) to individuals or groups of up to three people in recognition of outstanding achievements in physics. The award consists of a diploma, a medal, and 10,000 euros in prize money. The award has been established in 2012 by the Centro di Cultura Scientifica "Alessandro Volta", Edison S.p.A. and the European Physical Society.
Sir Tejinder Singh Virdee,, is a Kenyan-born British experimental particle physicist and Professor of Physics at Imperial College London. He is best known for originating the concept of the Compact Muon Solenoid (CMS) with a few other colleagues and has been referred to as one of the 'founding fathers' of the project. CMS is a world-wide collaboration which started in 1991 and now has over 3500 participants from 50 countries.
Moderna, Inc. is an American pharmaceutical and biotechnology company based in Cambridge, Massachusetts, that focuses on RNA therapeutics, primarily mRNA vaccines. These vaccines use a copy of a molecule called messenger RNA (mRNA) to carry instructions for proteins to produce an immune response. The company's name is derived from the terms "modified", "RNA", and "modern".
Peter Jenni, is an experimental particle physicist working at CERN. He is best known as one of the "founding fathers" of the ATLAS experiment at the CERN Large Hadron Collider together with a few other colleagues. He acted as spokesperson of the ATLAS Collaboration until 2009. ATLAS is a world-wide collaboration which started in 1992 involving roughly 3,000 physicists at 183 institutions in 38 countries. Jenni was directly involved in the experimental work leading to the discoveries of the W and Z bosons in the 1980s and the Higgs boson in 2012. He is (co-)author of about 1000 publications in scientific journals.
The Future Circular Collider (FCC) is a proposed particle accelerator with an energy significantly above that of previous circular colliders, such as the Super Proton Synchrotron, the Tevatron, and the Large Hadron Collider (LHC). The FCC project is considering three scenarios for collision types: FCC-hh, for hadron-hadron collisions, including proton-proton and heavy ion collisions, FCC-ee, for electron-positron collisions, and FCC-eh, for electron-hadron collisions.
An mRNAvaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules of antigen-encoding mRNA into cells, which use the designed mRNA as a blueprint to build foreign protein that would normally be produced by a pathogen or by a cancer cell. These protein molecules stimulate an adaptive immune response that teaches the body to identify and destroy the corresponding pathogen or cancer cells. The mRNA is delivered by a co-formulation of the RNA encapsulated in lipid nanoparticles that protect the RNA strands and help their absorption into the cells.
A COVID‑19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID‑19).
BioNTech SE is a global biotechnology company headquartered in Mainz that develops immunotherapies and vaccines, particularly for cancer and infectious diseases.
The Pfizer–BioNTech COVID-19 vaccine, sold under the brand name Comirnaty, is an mRNA-based COVID-19 vaccine developed by the German biotechnology company BioNTech. For its development, BioNTech collaborated with the American company Pfizer to carry out clinical trials, logistics, and manufacturing. It is authorized for use in humans to provide protection against COVID-19, caused by infection with the SARS-CoV-2 virus. The vaccine is given by intramuscular injection. It is composed of nucleoside-modified mRNA (modRNA) that encodes a mutated form of the full-length spike protein of SARS-CoV-2, which is encapsulated in lipid nanoparticles. Initial guidance recommended a two-dose regimen, given 21 days apart; this interval was subsequently extended to up to 42 days in the United States, and up to four months in Canada.
Drew Weissman is an American physician and immunologist known for his contributions to RNA biology. Weissman is the inaugural Roberts Family Professor in Vaccine Research, director of the Penn Institute for RNA Innovation, and professor of medicine at the Perelman School of Medicine at the University of Pennsylvania (Penn).
SARS-CoV-2, the virus that causes COVID-19, was isolated in late 2019. Its genetic sequence was published on 11 January 2020, triggering an urgent international response to prepare for an outbreak and hasten the development of a preventive COVID-19 vaccine. Since 2020, vaccine development has been expedited via unprecedented collaboration in the multinational pharmaceutical industry and between governments. By June 2020, tens of billions of dollars were invested by corporations, governments, international health organizations, and university research groups to develop dozens of vaccine candidates and prepare for global vaccination programs to immunize against COVID‑19 infection. According to the Coalition for Epidemic Preparedness Innovations (CEPI), the geographic distribution of COVID‑19 vaccine development shows North American entities to have about 40% of the activity, compared to 30% in Asia and Australia, 26% in Europe, and a few projects in South America and Africa.
The CureVac COVID-19 vaccine was a COVID-19 vaccine candidate developed by CureVac N.V. and the Coalition for Epidemic Preparedness Innovations (CEPI). The vaccine showed inadequate results in its Phase III trials with only 47% efficacy. In October 2021 CureVac abandoned further development and production plans for CVnCoV and refocused efforts on a cooperation with GlaxoSmithKline.
Robert Wallace Malone is an American physician and biochemist. His early work focused on mRNA technology, pharmaceuticals, and drug repurposing research. During the COVID-19 pandemic, Malone promoted misinformation about the safety and efficacy of COVID-19 vaccines.
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