5-Exo-hydroxycamphor dehydrogenase

5-exo-hydroxycamphor dehydrogenase
Identifiers
EC no.	1.1.1.327
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

5-exo-hydroxycamphor dehydrogenase (EC 1.1.1.327, F-dehydrogenase, FdeH) is an enzyme with systematic name 5-exo-hydroxycamphor:NAD⁺ oxidoreductase. ^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

5-exo-hydroxycamphor + NAD⁺${\displaystyle \rightleftharpoons }$ bornane-2,5-dione + NADH + H⁺

This enzyme contains Zn²⁺. It is isolated from Pseudomonas putida .

References

1. Rheinwald JG, Chakrabarty AM, Gunsalus IC (March 1973). "A transmissible plasmid controlling camphor oxidation in Pseudomonas putida". Proceedings of the National Academy of Sciences of the United States of America. 70 (3): 885–9. Bibcode:1973PNAS...70..885R. doi: 10.1073/pnas.70.3.885 . PMC   433381 . PMID   4351810.
2. Koga H, Yamaguchi E, Matsunaga K, Aramaki H, Horiuchi T (November 1989). "Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida". Journal of Biochemistry. 106 (5): 831–6. doi:10.1093/oxfordjournals.jbchem.a122939. PMID   2613690.
3. Aramaki H, Koga H, Sagara Y, Hosoi M, Horiuchi T (July 1993). "Complete nucleotide sequence of the 5-exo-hydroxycamphor dehydrogenase gene on the CAM plasmid of Pseudomonas putida (ATCC 17453)". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1174 (1): 91–4. doi:10.1016/0167-4781(93)90098-x. PMID   8334169.

External links

• 5-exo-hydroxycamphor+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)