Buglossoides arvensis

Last updated

Buglossoides arvensis
Lithospermum arvense W.jpg
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Boraginales
Family: Boraginaceae
Genus: Buglossoides
Species:
B. arvensis
Binomial name
Buglossoides arvensis
(L.) I.M.Johnst. (1954)
Synonyms [1]
  • Aegonychon arvense(L.) Gray (1821 publ. 1822)
  • Lithospermum arvenseL. (1753)
  • Margarospermum arvense(L.) Decne. (1840)
  • Rhytispermum arvense(L.) Link (1829)

Buglossoides arvensis (syn. Lithospermum arvense), known as field gromwell, corn gromwell, bastard alkanet, and stone seed, is a flowering plant of the family Boraginaceae. It is native to Europe and Asia, as far north as Korea, Japan and Russia, and as far south as Afghanistan and northern Pakistan. [2] It is known in other places as an introduced species, including much of North America and Australia. [3] [4]

Contents

Subspecies

Three subspecies are accepted. [1]

Uses

The European Union has granted the refined oil of the seed of Buglossoides arvensis novel food status and some farmers are growing it [5] commercially in the United Kingdom as a plant-variety patented (PVP) and trademarked cultivar (Ahiflower®). The seed oil contains high levels (63-72%) of omega-3 ALA (c18:3), omega-3 SDA (c18:4), and omega-6 GLA (c18:3) [6] and has GRAS (generally regarded as safe) review status from the US Food and Drug Administration, Canadian ingredient master file (IMF) registration and novel food status, and GMP+ Feed Support Product status in the EU for livestock and companion animals (including for defatted expeller press cake meal). The seed oil also has TGA Australia Complementary Medicines approval status, ANVISA/MAPA Brazil human and animal alimentary use approval, and limited food use approvals in Korea and Japan.

Refined Buglossoides oil has peer-reviewed published human clinical evidence from controlled dietary intervention trials showing up to 400% more efficient omega-3 EPA (c20:5) accrual in circulating cells vs flaxseed oil and has been shown to significantly upregulate the cytokine interleukin-10 (IL-10) in lipopolysaccharide (LPS) stimulated macrophages by +40% vs. control. [7] IL-10 is recognized as one of the immune modulatory signaling cytokines that moderates the inflammatory response after intensive exercise or immune challenge. Further, refined Buglossoides oil has been shown to form omega-3 DHA (C22:6) endogenously with comparable efficiency as pure marine DHA in mammals and maintain DHA levels similarly in the brain and liver. [8] It has also been shown in recent peer-reviewed research to promote live probiotic survival into the small intestine in the TIMS-1 simulated gut [9] and contribute beneficially to anti-neuroinflammation response in vitro [10] and synergistically to improved executive function and cognitive flexibility in healthy adults. [11] Based on its fatty acid composition, refined Buglossoides oil naturally provides the body a more diverse array of anti-inflammatory omega-3 and omega-6 (via GLA) substrates than derive from preformed EPA/DHA sources. These include SDA, ETA (C20:4n-3), GLA, and DGLA (C20:3n-6).

Seeds of Buglossoides have been reported in Ukrainian archeological sites dating back as far as 4000 BC where they were stored in clay pots, however the purpose and usage of the seeds has not been determined. In modern European arable agriculture, Buglossoides often appears as a weed species with poor competitive and non-invasive characteristics.

Related Research Articles

Omega−3 fatty acids, also called omega−3 oils, ω−3 fatty acids or n−3 fatty acids, are polyunsaturated fatty acids (PUFAs) characterized by the presence of a double bond three atoms away from the terminal methyl group in their chemical structure. They are widely distributed in nature, being important constituents of animal lipid metabolism, and they play an important role in the human diet and in human physiology. The three types of omega−3 fatty acids involved in human physiology are α-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). ALA can be found in plants, while DHA and EPA are found in algae and fish. Marine algae and phytoplankton are primary sources of omega−3 fatty acids. DHA and EPA accumulate in fish that eat these algae. Common sources of plant oils containing ALA include walnuts, edible seeds, and flaxseeds as well as hempseed oil, while sources of EPA and DHA include fish and fish oils, and algae oil.

<span class="mw-page-title-main">Flax</span> Flowering plant in the family Linaceae

Flax, also known as common flax or linseed, is a flowering plant, Linum usitatissimum, in the family Linaceae. It is cultivated as a food and fiber crop in regions of the world with temperate climates. In 2022, France produced 75% of the world's supply of flax.

Essential fatty acids, or EFAs, are fatty acids that are required by humans and other animals for normal physiological function that cannot be synthesized in the body.⁠ As they are not synthesized in the body, the essential fatty acids – alpha-linolenic acid (ALA) and linoleic acid – must be obtained from food or from a dietary supplement. Essential fatty acids are needed for various cellular metabolic processes and for the maintenance and function of tissues and organs. These fatty acids also are precursors to vitamins, cofactors, and derivatives, including prostaglandins, leukotrienes, thromboxanes, lipoxins, and others.

α-Linolenic acid Chemical compound

α-Linolenic acid, also known as alpha-linolenic acid (ALA), is an n−3, or omega-3, essential fatty acid. ALA is found in many seeds and oils, including flaxseed, walnuts, chia, hemp, and many common vegetable oils.

<span class="mw-page-title-main">Hemp oil</span> Oil from hemp seeds

Hemp oil is oil obtained by pressing hemp seeds. Cold pressed, unrefined hemp oil is dark to clear light green in color, with a nutty flavor. The darker the color, the grassier the flavour. It should not be confused with hash oil, a tetrahydrocannabinol-containing oil made from the Cannabis flower.

γ-Linolenic acid or GLA is an n−6, or omega-6, fatty acid found primarily in seed oils. When acting on GLA, arachidonate 5-lipoxygenase produces no leukotrienes and the conversion by the enzyme of arachidonic acid to leukotrienes is inhibited.

Linoleic acid (LA) is an organic compound with the formula HOOC(CH2)7CH=CHCH2CH=CH(CH2)4CH3. Both alkene groups are cis. It is a fatty acid sometimes denoted 18:2 (n−6) or 18:2 cis-9,12. A linoleate is a salt or ester of this acid.

<span class="mw-page-title-main">Vegetarian nutrition</span> Nutritional and human health aspects of vegetarian diets

Vegetarian nutrition is the set of health-related challenges and advantages of vegetarian diets.

<span class="mw-page-title-main">Eicosapentaenoic acid</span> Chemical compound

Eicosapentaenoic acid (EPA; also icosapentaenoic acid) is an omega−3 fatty acid. In physiological literature, it is given the name 20:5(n−3). It also has the trivial name timnodonic acid. In chemical structure, EPA is a carboxylic acid with a 20-carbon chain and five cis double bonds; the first double bond is located at the third carbon from the omega end.

<span class="mw-page-title-main">Docosahexaenoic acid</span> Chemical compound

Docosahexaenoic acid (DHA) is an omega−3 fatty acid that is an important component of the human brain, cerebral cortex, skin, and retina. It is given the fatty acid notation 22:6(n−3). It can be synthesized from alpha-linolenic acid or obtained directly from maternal milk (breast milk), fatty fish, fish oil, or algae oil. The consumption of DHA (e.g., from fatty fish such as salmon, herring, mackerel and sardines) contributes to numerous physiological benefits, including cognition. As a component of neuronal membranes, the function of DHA is to support neuronal conduction and to allow the optimal functioning of neuronal membrane proteins (such as receptors and enzymes).

The lignans are a large group of low molecular weight polyphenols found in plants, particularly seeds, whole grains, and vegetables. The name derives from the Latin word for "wood". Lignans are precursors to phytoestrogens. They may play a role as antifeedants in the defense of seeds and plants against herbivores.

<span class="mw-page-title-main">Corn oil</span> Oil from the seeds of corn

Corn oil or maize oil (British) is oil extracted from the germ of corn (maize). Its main use is in cooking, where its high smoke point makes refined corn oil a valuable frying oil. It is also a key ingredient in some margarines. Corn oil is generally less expensive than most other types of vegetable oils.

<span class="mw-page-title-main">Stearidonic acid</span> Chemical compound

Stearidonic acid (SDA: C18H28O2; 18:4, n-3) is an ω-3 fatty acid, sometimes called moroctic acid.

Fatty acid desaturases are a family of enzymes that convert saturated fatty acids into unsaturated fatty acids and polyunsaturated fatty acids. For the common fatty acids of the C18 variety, desaturases convert stearic acid into oleic acid. Other desaturases convert oleic acid into linoleic acid, which is the precursor to alpha-linolenic acid, gamma-linolenic acid, and eicosatrienoic acid.

<span class="mw-page-title-main">Essential fatty acid interactions</span>

There is a wide variety of fatty acids found in nature. Two classes of fatty acids are considered essential, the omega-3 and omega-6 fatty acids. Essential fatty acids are necessary for humans but cannot be synthesized by the body and must therefore be obtained from food. Omega-3 and omega-6 are used in some cellular signaling pathways and are involved in mediating inflammation, protein synthesis, and metabolic pathways in the human body.

<i>Rhamphospermum arvense</i> Species of plant

Rhamphospermum arvense, the charlock mustard, field mustard, wild mustard, or just charlock, is an annual or winter annual plant in the family Brassicaceae. It is found in the fields of North Africa, Asia, Europe, and some other areas where it has been transported and naturalized. Pieris rapae, the small white butterfly, and Pieris napi, the green veined white butterfly, are significant consumers of charlock during their larval stages.

A wax ester (WE) is an ester of a fatty acid and a fatty alcohol. Wax esters are the main components of three commercially important waxes: carnauba wax, candelilla wax, and beeswax.

<span class="mw-page-title-main">Oxylipin</span> Class of lipids

Oxylipins constitute a family of oxygenated natural products which are formed from fatty acids by pathways involving at least one step of dioxygen-dependent oxidation. These small polar lipid compounds are metabolites of polyunsaturated fatty acids (PUFAs) including omega-3 fatty acids and omega-6 fatty acids. Oxylipins are formed by enyzmatic or non-enzymatic oxidation of PUFAs.

<span class="mw-page-title-main">Senior dog diet</span> Pet foods catered toward senior pets

Senior dog food diets are pet foods that are catered toward the senior or mature pet population. The senior dog population consists of dogs that are over the age of seven for most dog breeds, though in general large and giant breed dogs tend to reach this life stage earlier when compared to smaller breed dogs. Senior dog foods contain nutrients and characteristics that are used to improve the health of the aging dog. Aging in dogs causes many changes to occur physiologically that will require a change in nutrient composition of their diet.

References

  1. 1 2 Buglossoides arvensis (L.) I.M.Johnst. Plants of the World Online . Retrieved 29 July 2024.
  2. "Lithospermum arvense Linnaeus, Sp. Pl. 1: 132. 1753". Flora of China.
  3. ^ USDA Plants Profile
  4. ^"Buglossoides arvensis". Australian Plant Name Index (APNI), IBIS database. Centre for Plant Biodiversity Research, Australian Government, Canberra. Retrieved 20 March 2012.
  5. ^ Nosowitz, Dan (19 November 2015). "What Is This Weird Weed, and Why Are Farmers and Health Nuts So Into It?". Modern Farmer. Retrieved 30 November 2015.
  6. Lefort (2016) Consumption of Buglossoides arvensis seed oil is safe and increases tissue long-chain n-3 fatty acid content more than flax seed oil. J Nutr Sci 5:e2, 1-12. Retrieved 10 Jun 2022.
  7. Lefort (2017) Dietary Buglossoides arvensis oil increases circulating n-3 polyunsaturated fatty acids in a dose-dependent manner and enhances lipopolysaccharide-stimulated whole blood interleukin-10—a randomized placebo-controlled trial. Nutrients 9:261; 1-17. Retrieved 10 Jun 2022.
  8. Metherel A (2021) Determining plasma and tissue DHA turnover from Ahiflower® oil, flaxseed oil and DHA using compound specific isotopic analysis. J Am Oil Chem Soc 2021;98(Suppl. 1):242–243.
  9. Venema K et al. (2020) Survival of a probiotic-containing product using capsule-within-capsule technology in an in vitro model of the stomach and small intestine (TIM-1). Beneficial Microbes 2020; 11(4): 403-409
  10. Cumberford G et al. (2023) Methods and compositions with purified Bombyx morii cocoon silk fiber and refined Buglossoides arvensis seed oil providing anti-inflammatory effects and neuroprotection for disease states. Patent #US 11707497B2 (July 25, 2023), p. 101.
  11. Lanou A (2023) A randomized, placebo-controlled clinical trial of a novel dietary supplement (Braini) on standardized CNS vital signs cognitive performance parameters in adults. J Integr Complement Med. 2023; May;29(5):303-312.