Collagen, type XXII, alpha 1

COL22A1
Identifiers
Aliases	COL22A1 , collagen, type XXII, alpha 1, collagen type XXII alpha 1 chain
External IDs	OMIM: 610026 MGI: 1916950 HomoloGene: 43567 GeneCards: COL22A1
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	71,906,076 bp
RNA expression pattern
	Top expressed in
	pituitary gland; ; anterior pituitary; ; tibia; ; corpus epididymis; ; seminal vesicula; ; ganglionic eminence; ; smooth muscle tissue; ; prostate; ; synovial joint; ; islet of Langerhans;
	Top expressed in
	spermatid; ; body of femur; ; fossa; ; seminiferous tubule; ; ankle; ; trigeminal ganglion; ; calvaria; ; soleus muscle; ; molar; ; spermatocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	extracellular matrix structural constituent ;
Cellular component	cytoplasm ; extracellular region ; collagen ; endoplasmic reticulum lumen ; extracellular space ; extracellular matrix ;
Biological process	extracellular matrix organization ;
	Sources:Amigo / QuickGO
Orthologs
	169044
	69700
	n/a
	ENSMUSG00000079022
	Q8NFW1
	n/a
	NM_152888
	NM_027174
	NP_690848
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 22, 2023

COL22A1 is a human gene encoding for collagen. The associated protein is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during muscle contraction. ^[4]

Related Research Articles

Enaptin also known as nesprin-1 or synaptic nuclear envelope protein 1 (syne-1) is an actin-binding protein that in humans that is encoded by the SYNE1 gene.

Collagen alpha-1 (XXVII) chain (COL27A1) is a protein that in humans is encoded by the COL27A1 gene.

Collagen alpha-2(I) chain is a protein that in humans is encoded by the COL1A2 gene.

Zinc finger protein 3 is a protein that in humans is encoded by the ZNF3 gene.

Collagen alpha-1(VIII) chain is a protein that in humans is encoded by the COL8A1 gene.

Collagen alpha-3(V) chain is a protein that in humans is encoded by the COL5A3 gene.

Collagen alpha-1(XVI) chain is a protein that in humans is encoded by the COL16A1 gene.

Zinc finger and BTB domain-containing protein 7B is a protein that in humans is encoded by the ZBTB7B gene. ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes and has a role in development.[supplied by OMIM]

Integrin alpha-11 is a protein that, in humans, is encoded by the ITGA11 gene.

Collagen alpha-1(XXVI) chain is a protein that in humans is encoded by the EMID2 gene.

Collagen alpha-1(XXI) chain is a protein that in humans is encoded by the COL21A1 gene. The protein is an extracellular matrix component of blood vessel walls, secreted by smooth-muscle cells. The protein may contribute to the extracellular matrix assembly of the vascular network during blood vessel formation.

Collagen, type XXVIII, alpha 1 also known as COL28A1 is a protein that in humans is encoded by the COL28A1 gene. This protein belongs to a class of collagens that contain von Willebrand factor type A domains. The protein is encoded by the COL28A1 gene which contains 45 exons and is found of the p arm of chromosome 7.

Collagen alpha-5(VI) chain also known as von Willebrand factor A domain-containing protein 4 is a protein that in humans is encoded by the COL6A5 gene.

Homeobox protein Mohawk, also known as iroquois homeobox protein-like 1, is a protein that in humans is encoded by the MKX gene. MKX is a member of an Iroquois (IRX) family-related class of 'three-amino acid loop extension' (TALE) atypical homeobox proteins characterized by 3 additional amino acids in the loop region between helix I and helix II of the homeodomain.

Zinc finger and BTB domain containing 11 is a protein that in humans is encoded by the ZBTB11 gene.

BarH-like homeobox 2 is a protein in humans that is encoded by the BARHL2 gene.

Forkhead box B1 is a protein that in humans is encoded by the FOXB1 gene.

Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein.

Collagen beta(1-O)galactosyltransferase 1 is a protein that in humans is encoded by the COLGALT1 gene.

Prolyl 4-hydroxylase, transmembrane is a protein that in humans is encoded by the P4HTM gene.

References

1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000079022 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "COL22A1 collagen type XXII alpha 1 chain". NCBI. 25 May 2017. Retrieved 18 September 2017.

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[refGRCm38Ensembl-1] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000079022 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "COL22A1 collagen type XXII alpha 1 chain". NCBI. 25 May 2017. Retrieved 18 September 2017.

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