According to Baianu et al. CSB is a field that has only a partial overlap with the more conventional concepts of complex systems theory and systems biology, because CSB is concerned with philosophy and human consciousness. Moreover, mathematics can model a wide range of complex systems, but this is claimed not to be relevant.[5]
Network Representation of a Complex Adaptive System
Complexity of organisms and biosphere
There is no satisfying definition of complexity in biology.[6][7]
According to Rosen, most complex system models are not about biological subjects, such as genomes and organisms,[3][8] although biology has been successfully modelled since the 19th century.[9][10]
Regarding ontology (the philosophical metaphysics of reality), one is assuming that there is a hierarchy of complexity levels of organization distinct from reality.[5][12][13]
Baianu et al. claim that taxonomic ranks such as order, family, genus, species, etc. reflect a hierarchy of complexity levels of organization in biology.[5]
Because of their variability, ability to heal and self-reproduce, and so on, organisms are defined as 'meta-systems' of simpler systems in CSB.[5][14] A meta-system is a system of systems.[14]Autopoiesis also models such a biological system of systems,[15] however, Baianu et al. claim that in biology a meta-system is not equivalent to such a system of systems.[5] They also claim it differs from the meta-system defined in a blog by Kent D. Palmer[16][17] because organisms are different from machines or robots.[5] If, according to Hopcroft et al., robots or automata can be defined by five qualities: states, startup state, input and output sets/alphabet and transition function,[18] organisms are different.[5]
Topics in complex systems biology
a complex signal transduction pathway
The following is a list of topics covered in complex systems biology:
↑ Donald Snooks, Graeme, "A general theory of complex living systems: Exploring the demand side of dynamics", Complexity, vol. 13, no. 6, July/August 2008.
1 2 Rosen, R. (1958b). "The Representation of Biological Systems from the Standpoint of the Theory of Categories". Bulletin of Mathematical Biophysics. 20 (4): 317–341. doi:10.1007/bf02477890.
1 2 Rosen, R. (1958a). "A Relational Theory of Biological Systems". Bulletin of Mathematical Biophysics. 20 (3): 245–260. doi:10.1007/bf02478302.
↑ Bonner, J. T. 1988. The Evolution of Complexity by Means of Natural Selection. Princeton: Princeton University Press.
↑ Heylighen, Francis (2008). "Complexity and Self-Organization". In Bates, Marcia J.; Maack, Mary Niles. Encyclopedia of Library and Information Sciences. CRC. ISBN978-0-8493-9712-7
↑ ^ Heylighen, Francis (2008). "Complexity and Self-Organization". In Bates, Marcia J.; Maack, Mary Niles. Encyclopedia of Library and Information Sciences. CRC. ISBN978-0-8493-9712-7
↑ Thompson, D'Arcy W., 1992. On Growth and Form. Dover reprint of 1942, 2nd ed. (1st ed., 1917). ISBN0-486-67135-6
↑ http://hdl.handle.net/10101/npre.2011.6115.1 Wallace, Rodrick. When Spandrels Become Arches: Neural crosstalk and the evolution of consciousness. Available from Nature Precedings (2011)
↑ Hoff, M.A., Roggia, K.G., Menezes, P.B.:(2004). Composition of Transformations: A Framework for Systems with Dynamic Topology. International Journal of Computing Anticipatory System's 14:259–270
↑ Rosen, R. 1960. (1960). "A quantum-theoretic approach to genetic problems". Bulletin of Mathematical Biophysics. 22 (3): 227–255. doi:10.1007/BF02478347.
↑ Rosen, R.: 1958b (1958). "The Representation of Biological Systems from the Standpoint of the Theory of Categories". Bulletin of Mathematical Biophysics. 20 (4): 317–341. doi:10.1007/BF02477890.
References cited
Baianu, I. C., Computer Models and Automata Theory in Biology and Medicine., Monograph, Ch.11 in M. Witten (Editor), Mathematical Models in Medicine, vol. 7., Vol. 7: 1513-1577 (1987),Pergamon Press:New York, (updated by Hsiao Chen Lin in 2004 ISBN0-08-036377-6
Renshaw, E., Modelling biological populations in space and time. C.U.P., 1991. ISBN0-521-44855-7
Rosen, Robert.1991, Life Itself: A Comprehensive Inquiry into the Nature, Origin, and Fabrication of Life, Columbia University Press, published posthumously:
Rosen, Robert .1970. Dynamical system theory in biology. New York, Wiley-Interscience. ISBN0-471-73550-7
Rosen, Robert. 2000, Essays on Life Itself, Columbia University Press.
Kurata, Hiroyuki; Taira, K; Kitano, H (1999). "Synthesis and Analysis of a Biological System". Genome Informatics Series (Sers 10): 352–353. OCLC203735966.
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