Cordyceps militaris

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Cordyceps militaris
2010-08-06 Cordyceps militaris 1.jpg
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Fungi
Division: Ascomycota
Class: Sordariomycetes
Order: Hypocreales
Family: Cordycipitaceae
Genus: Cordyceps
Species:
C. militaris
Binomial name
Cordyceps militaris
(L.) Fr. (1818)
Synonyms [1]

Clavaria militarisL. (1753)
Sphaeria militaris(L.) J.F. Gmel. (1792)
Cordylia militaris(L.) Fr. (1818)
Hypoxylon militare(L.) Mérat, (1821)
Xylaria militaris(L.) Gray (1821)
Corynesphaera militaris(L.) Dumort. (1822)
Kentrosporium militare(L.) Wallr. (1844)
Torrubia militaris(L.) Tul. & C. Tul. (1865)

Contents

Cordyceps militaris, commonly known as the caterpillar fungus, [2] is a species of fungus in the family Cordycipitaceae, and the type species of the genus Cordyceps , which consists of hundreds of species. [3] The species was originally described by Carl Linnaeus in 1753 as Clavaria militaris. [1] Cordyceps militaris parasitizes insects and is used in traditional Chinese medicine.

It is commonly marketed as a dietary supplement for various health benefits but lacks sufficient scientific evidence for safety or effectiveness, and quality can vary due to inconsistent processing and labeling.

Description

The fungus forms 1–8 centimetres (123+14 in) high, club-shaped [4] and orange/red fruiting bodies, which grow out of dead underground pupae. The club is covered with the stroma, into which the actual fruit bodies, the perithecia, are inserted. The surface appears roughly punctured. The inner fungal tissue is whitish to pale orange.

Microscopic features

The spores are smooth, hyaline, long-filiform, and often septate. They decompose to maturity in 3–7  μm × 1–1.2 μm sub pores. The asci are long and cylindrical. Sometimes an anamorphic state, which is Isaria , is found. Masses of white mycelia form around the parasitized insect; however, these may not be of the same species.

Similar species

There are over 400 wild Cordyceps species. [5] Some similar species include C. sobolifera, Elaphocordyceps capitata, and E. ophioglossoides. [4]

Distribution and habitat

Many authors consider C. militaris quite common, spread throughout the Northern Hemisphere, [6] and fruiting bodies appear in Europe from August to November.

Uses

Cordyceps militaris
Information icon.svg
Smooth icon.pngSmooth hymenium
No cap icon.svgNo distinct cap
NA cap icon.svg Hymenium attachment is irregular or not applicable
Bare stipe icon.svg Stipe is bare
Parasitic fungus.svgEcology is parasitic
Mycomorphbox Edible.pngMycomorphbox Inedible.pngEdibility is edible or inedible

C. militaris can be cultivated in a variety of media, including silkworm pupae, rice, and liquid nutrition.[ citation needed ] It is cultivated in China, Vietnam, Taiwan, and Indonesia. [7]

It is considered inedible or "probably edible" by North American field guides. [8] [4] In Asia the fruiting body is cooked as a mushroom in dishes like chicken soup, [9] pork bone soup [10] and hot pot. It is approved as a novel food in China.[ citation needed ]

It is commonly marketed as a dietary supplement for various health benefits but lacks sufficient scientific evidence for safety or effectiveness, and quality can vary due to inconsistent processing and labeling. [11]

C. militaris crops can be affected by pathogenic molds that parasitize and kill the fungus. [12] [13]

Phytochemistry

C. militaris produces cordycepin, a nucleoside analog of adenosine. [14]

Drug production

For cordycepin to accumulate, the fungus also produces pentostatin to protect cordycepin from adenosine deaminase. Pentostatin (Nipent) is used in chemotherapy for people with hairy cell leukemia. [15]

References

  1. 1 2 "GSD Species Synonymy: Cordyceps militaris (L.) Fr". Species Fungorum. CAB International. Retrieved 2014-05-20.
  2. Arora, David (1986) [1979]. Mushrooms Demystified: A Comprehensive Guide to the Fleshy Fungi (2nd ed.). Berkeley, California: Ten Speed Press. p. 882. ISBN   978-0-89815-170-1.
  3. Ng, T B; Wang, H X (2010-02-18). "Pharmacological actions of Cordyceps, a prized folk medicine" . Journal of Pharmacy and Pharmacology. 57 (12): 1509–1519. doi:10.1211/jpp.57.12.0001. ISSN   0022-3573. PMID   16354395. S2CID   35081231.
  4. 1 2 3 Davis, R. Michael; Sommer, Robert; Menge, John A. (2012). Field Guide to Mushrooms of Western North America. Berkeley: University of California Press. pp. 381–382. ISBN   978-0-520-95360-4. OCLC   797915861.
  5. Sung, Gi-Ho; Nigel L. Hywel-Jones; Jae-Mo Sung; J. Jennifer Luangsa-ard; Bhushan Shrestha & Joseph W. Spatafora (2007). "Phylogenetic classification of Cordyceps and the clavicipitaceous fungi". Stud Mycol. 57 (1): 5–59. doi:10.3114/sim.2007.57.01. PMC   2104736 . PMID   18490993.
  6. Pilz des Jahres 2007: Cordyceps militaris (L.) Link, Puppenkernkeule
  7. "Taiwanese company cultivates cordyceps in Indonesia". Antara News. 10 December 2016.
  8. Phillips, Roger (2010). Mushrooms and Other Fungi of North America. Buffalo, NY: Firefly Books. p. 379. ISBN   978-1-55407-651-2.
  9. "虫草花淮山杞子鸡汤". 心食谱.
  10. "Cordyceps militaris pork bone soup". Simple Chinese Food.
  11. "Mushrooms in dietary supplements". Operation Supplement Safety. Consortium for Health and Military Performance. 2020-07-29. Retrieved 2025-05-19.
  12. Nguyen, Trung Thanh; Le, Thi Nguyen-Gia; Nguyen, Thuan Huy (17 October 2023). "First report of emerging fungal pathogens of Cordyceps militaris in Vietnam". Scientific Reports. 13 (1): 17669. doi: 10.1038/s41598-023-43951-9 . PMC   10582018 . PMID   37848482.
  13. Peng, Huanhuan; Cong, Yunlong; Zhao, Yitong; Liu, Zhenghui; Li, Yu (October 2024). "Trichoderma gamsii, a new pathogen causing disease on cultivated mushroom Cordyceps militaris in China". Crop Protection. 184 106864. doi:10.1016/j.cropro.2024.106864. preprint
  14. Tuli, Hardeep S.; Sharma, Anil K.; Sandhu, Sardul S.; Kashyap, Dharambir (2013). "Cordycepin: A bioactive metabolite with therapeutic potential". Life Sciences. 93 (23). Elsevier BV: 863–869. doi:10.1016/j.lfs.2013.09.030. ISSN   0024-3205. PMID   24121015.
  15. "Pentostatin". Drugs.com. 17 March 2025. Retrieved 20 May 2025.