Dacryoscintigraphy

Last updated
Dacryoscintigraphy
Lacrimal Scintigraphy.png
Synonyms microscintigraphy
nuclear dacryocystogram
nuclear lacrimal scan
lacrimal scintillography
ICD-10-PCS C8191ZZ
LOINC 39670-5

Dacryoscintigraphy (DSG), also known as lacrimal scintigraphy, is a nuclear medicine technique for imaging the lacrimal apparatus. It is used to identify obstructions, for example in the lacrimal duct, nasal cavity or nasolacrimal duct.

Contents

Procedure

The typical procedure involves use of Technetium-99m colloid, or in some cases pertechnetate. The colloid is prepared with an activity of approximately 20 megabecquerels in 1 millilitre (ml). Patients place their head in a support and chin rest and a single drop of 0.01 ml is delivered to each eye. Imaging with a gamma camera commences immediately, with a number of images acquired over 15 minutes. [1] [2]

Clinical applications

Typical indications include epiphora and dacryocystitis. [3]

DSG allows quantification of tear turnover and drainage. [4] Various quantification models have been developed, which must account for the variable drainage of asymptomatic systems. [5] Some drugs administered to the eye via eye drops, such as beta blockers for glaucoma, can be hazardous if quickly drained and absorbed through the nasolacrimal duct. DSG is considered the best method to quantitatively assess the proportion of the dose drained in this way. [6] It can also be useful in assessing functional problems, where the lacrimal system appears unobstructed, and for post-operative progress. [7] [8]

Advantages of DSG over dacrocystography include better functional information and a lack of injection. [9] DSG does not provide precise localisation and may not be useful in cases of complete obstruction. [10]

History

The technique was first introduced in 1972. [11]

Related Research Articles

<span class="mw-page-title-main">Tears</span> Clear liquid secreted from glands in eyes of mammals

Tears are a clear liquid secreted by the lacrimal glands found in the eyes of all land mammals. Tears are made up of water, electrolytes, proteins, lipids, and mucins that form layers on the surface of eyes. The different types of tears—basal, reflex, and emotional—vary significantly in composition.

<span class="mw-page-title-main">Lacrimal bone</span> Smallest and most fragile bone of the human skull and face

The lacrimal bones are two small and fragile bones of the facial skeleton; they are roughly the size of the little fingernail and situated at the front part of the medial wall of the orbit. They each have two surfaces and four borders. Several bony landmarks of the lacrimal bones function in the process of lacrimation. Specifically, the lacrimal bones help form the nasolacrimal canal necessary for tear translocation. A depression on the anterior inferior portion of one bone, the lacrimal fossa, houses the membranous lacrimal sac. Tears, from the lacrimal glands, collect in this sac during excessive lacrimation. The fluid then flows through the nasolacrimal duct and into the nasopharynx. This drainage results in what is commonly referred to a runny nose during excessive crying or tear production. Injury or fracture of the lacrimal bone can result in posttraumatic obstruction of the lacrimal pathways.

<span class="mw-page-title-main">Orbit (anatomy)</span> Cavity or socket of the skull in which the eye and its appendages are situated

In anatomy, the orbit is the cavity or socket/hole of the skull in which the eye and its appendages are situated. "Orbit" can refer to the bony socket, or it can also be used to imply the contents. In the adult human, the volume of the orbit is 30 millilitres, of which the eye occupies 6.5 ml. The orbital contents comprise the eye, the orbital and retrobulbar fascia, extraocular muscles, cranial nerves II, III, IV, V, and VI, blood vessels, fat, the lacrimal gland with its sac and duct, the eyelids, medial and lateral palpebral ligaments, cheek ligaments, the suspensory ligament, septum, ciliary ganglion and short ciliary nerves.

<span class="mw-page-title-main">Eye surgery</span> Surgery performed on the eye or its adnexa

Eye surgery, also known as ophthalmic surgery or ocular surgery, is surgery performed on the eye or its adnexa. Eye surgery is part of ophthalmology and is performed by an ophthalmologist or eye surgeon. The eye is a fragile organ, and requires due care before, during, and after a surgical procedure to minimize or prevent further damage. An eye surgeon is responsible for selecting the appropriate surgical procedure for the patient, and for taking the necessary safety precautions. Mentions of eye surgery can be found in several ancient texts dating back as early as 1800 BC, with cataract treatment starting in the fifth century BC. It continues to be a widely practiced class of surgery, with various techniques having been developed for treating eye problems.

<span class="mw-page-title-main">Dry eye syndrome</span> Medical condition of dry eyes

Dry eye syndrome, also known as keratoconjunctivitis sicca, is the condition of having dry eyes. Symptoms include dryness in the eye, irritation, redness, discharge, blurred vision, and easily fatigued eyes. Symptoms range from mild and occasional to severe and continuous. Dry eye syndrome can lead to blurred vision, instability of the tear film, increased risk of damage to the ocular surface such as scarring of the cornea, and changes in the eye including the neurosensory system.

<span class="mw-page-title-main">Nasolacrimal duct</span> Carries tears from the lacrimal sac of the eye into the nasal cavity.

The nasolacrimal duct carries tears from the lacrimal sac of the eye into the nasal cavity. The duct begins in the eye socket between the maxillary and lacrimal bones, from where it passes downwards and backwards. The opening of the nasolacrimal duct into the inferior nasal meatus of the nasal cavity is partially covered by a mucosal fold.

<span class="mw-page-title-main">Scintigraphy</span> Diagnostic imaging test in nuclear medicine

Scintigraphy, also known as a gamma scan, is a diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue (radiopharmaceuticals) are taken internally and the emitted gamma radiation is captured by gamma cameras, which are external detectors that form two-dimensional images in a process similar to the capture of x-ray images. In contrast, SPECT and positron emission tomography (PET) form 3-dimensional images and are therefore classified as separate techniques from scintigraphy, although they also use gamma cameras to detect internal radiation. Scintigraphy is unlike a diagnostic X-ray where external radiation is passed through the body to form an image.

<span class="mw-page-title-main">Bone scintigraphy</span> Nuclear medicine imaging technique

A bone scan or bone scintigraphy is a nuclear medicine imaging technique of the bone. It can help diagnose a number of bone conditions, including cancer of the bone or metastasis, location of bone inflammation and fractures, and bone infection (osteomyelitis).

<span class="mw-page-title-main">Radioisotope renography</span>

Radioisotope renography is a form of medical imaging of the kidneys that uses radiolabelling. A renogram, which may also be known as a MAG3 scan, allows a nuclear medicine physician or a radiologist to visualize the kidneys and learn more about how they are functioning. MAG3 is an acronym for mercapto acetyl tri glycine, a compound that is chelated with a radioactive element – technetium-99m.

<span class="mw-page-title-main">Lacrimal sac</span> Upper, dilated end of the nasolacrimal duct

The lacrimal sac or lachrymal sac is the upper dilated end of the nasolacrimal duct, and is lodged in a deep groove formed by the lacrimal bone and frontal process of the maxilla. It connects the lacrimal canaliculi, which drain tears from the eye's surface, and the nasolacrimal duct, which conveys this fluid into the nasal cavity. Lacrimal sac occlusion leads to dacryocystitis.

<span class="mw-page-title-main">Posterior lacrimal crest</span> Bony ridge on the orbital surface of the lacrimal bone

The posterior lacrimal crest is a vertical bony ridge on the orbital surface of the lacrimal bone. It divides the bone into two parts. It gives origin to the lacrimal part of the orbicularis oculi muscle.

Oculoplastics, or oculoplastic surgery, includes a wide variety of surgical procedures that deal with the orbit, eyelids, tear ducts, and the face. It also deals with the reconstruction of the eye and associated structures.

<span class="mw-page-title-main">Dacryocystorhinostomy</span> Surgical procedure to bypass the tear ducts

Dacryocystorhinostomy (DCR) is a surgical procedure to restore the flow of tears into the nose from the lacrimal sac when the nasolacrimal duct does not function.

<span class="mw-page-title-main">Dacryocystitis</span> Infection of the lacrimal sac of the eye

Dacryocystitis is an infection of the lacrimal sac, secondary to obstruction of the nasolacrimal duct at the junction of the lacrimal sac. The term derives from Greek dákryon 'tear' cysta 'sac' and -itis 'inflammation'. It causes pain, redness, and swelling over the inner aspect of the lower eyelid and epiphora. When nasolacrimal duct obstruction is secondary to a congenital barrier it is referred to as dacryocystocele. It is most commonly caused by Staphylococcus aureus and Streptococcus pneumoniae. The most common complication is corneal ulceration, frequently in association with S. pneumoniae. The mainstays of treatment are oral antibiotics, warm compresses, and relief of nasolacrimal duct obstruction by dacryocystorhinostomy.

A punctal plug, also known as tear duct plug or lacrimal plug, is a small medical device that is inserted into the tear duct (puncta) of an eye to block the duct. This prevents the drainage of liquid from the eye. They are used to treat dry eye.

<span class="mw-page-title-main">Epiphora (medicine)</span> Outflow of tears from the eye without crying

Epiphora is an overflow of tears onto the face, other than caused by normal crying. It is a clinical sign or condition that constitutes insufficient tear film drainage from the eyes, in that tears will drain down the face rather than through the nasolacrimal system.

<span class="mw-page-title-main">Cholescintigraphy</span> Medical imaging of hepatobiliary tract using radiotracers

Cholescintigraphy or hepatobiliary scintigraphy is scintigraphy of the hepatobiliary tract, including the gallbladder and bile ducts. The image produced by this type of medical imaging, called a cholescintigram, is also known by other names depending on which radiotracer is used, such as HIDA scan, PIPIDA scan, DISIDA scan, or BrIDA scan. Cholescintigraphic scanning is a nuclear medicine procedure to evaluate the health and function of the gallbladder and biliary system. A radioactive tracer is injected through any accessible vein and then allowed to circulate to the liver, where it is excreted into the bile ducts and stored by the gallbladder until released into the duodenum.

<span class="mw-page-title-main">Dacryocystocele</span> Medical condition

Dacryocystocele (Dacryocystitis) or timo cyst is a benign, bluish-gray mass in the inferomedial canthus that develops within a few days or weeks after birth. The uncommon condition forms as a result as a consequence of narrowing or obstruction of the nasolacrimal duct, usually during prenatal development. Nasolacrimal duct obstruction disrupts the lacrimal drainage system, eventually creating a swelling cyst in the lacrimal sac area by the nasal cavity. The location of the cyst can cause respiratory dysfunction, compromising the airway. The obstruction ultimately leads to epiphora, an abundance of tear production.

<span class="mw-page-title-main">Nasolacrimal duct obstruction</span> Blockage of the tear ducts

Nasolacrimal duct obstruction is the obstruction of the nasolacrimal ducts and may be either congenital or acquired. Obstruction of the nasolacrimal ducts leads to the excess overflow of tears called epiphora.

<span class="mw-page-title-main">Gastric emptying study</span> Nuclear medicine study of the stomachs ability to empty

A gastric emptying study is a nuclear medicine study which provides an assessment of the stomach's ability to empty. It may be used if there are complications after gastric surgery, for gastric reflux, or suspected gastroparesis amongst other indications. Scintigraphy that uses gamma cameras to create two-dimensional images is generally regarded as the gold standard for gastric emptying.

References

  1. "Lacrimal Scintigraphy v2" (PDF). BNMS. June 2018. Retrieved 25 August 2021.
  2. Costa, Ines M.; Pereira, Luisa R.; Jessop, Maryam; Shawgi, Mohamed; James, Jackie M.; Dizdarevic, Sabina (April 2021). "Lacrimal scintigraphy BNMS Guidelines". Nuclear Medicine Communications. 42 (4): 459–467. doi:10.1097/MNM.0000000000001358. ISSN   0143-3636. PMID   33395194. S2CID   230665389.
  3. Prakash, Dibya (2014-04-10). Nuclear Medicine: A Guide for Healthcare Professionals and Patients. Springer Science & Business Media. p. 81. ISBN   9788132218265.
  4. Detorakis, EfstathiosT; Zissimopoulos, Athanassios; Ioannakis, Konstantinos; Kozobolis, VassiliosP (2014). "Lacrimal Outflow Mechanisms and the Role of Scintigraphy: Current Trends". World Journal of Nuclear Medicine. 13 (1): 16–21. doi: 10.4103/1450-1147.138569 . PMC   4149763 . PMID   25191107.
  5. Tomlinson, Alan; Khanal, Santosh (April 2005). "Assessment of Tear Film Dynamics: Quantification Approach". The Ocular Surface. 3 (2): 81–95. doi:10.1016/S1542-0124(12)70157-X. PMID   17131012.
  6. Wilson, Clive G (August 1999). "Assessing ocular drug delivery with lachrimal scintigraphy". Pharmaceutical Science & Technology Today. 2 (8): 321–326. doi:10.1016/S1461-5347(99)00176-5. PMID   10441276.
  7. Chan, WengOnn; Malhotra, Raman; Kakizaki, Hirohiko; Leibovitch, Igal; Selva, Dinesh (September 2012). "Perspective: what does the term functional mean in the context of epiphora?". Clinical & Experimental Ophthalmology. 40 (7): 749–754. doi:10.1111/j.1442-9071.2012.02791.x. PMID   22429759. S2CID   20761303.
  8. Lefebvre, Daniel R.; Freitag, Suzanne K. (19 November 2012). "Update on Imaging of the Lacrimal Drainage System". Seminars in Ophthalmology. 27 (5–6): 175–186. doi:10.3109/08820538.2012.711413. PMID   23163273. S2CID   27031370.
  9. Bennett, Paige A.; Oza, Umesh D. (2015-10-13). Diagnostic Imaging: Nuclear Medicine E-Book. Elsevier Health Sciences. p. 304. ISBN   9780323400442.
  10. Sagili, Suresh; Selva, Dinesh; Malhotra, Raman (10 April 2012). "Lacrimal Scintigraphy: "Interpretation More Art than Science"". Orbit. 31 (2): 77–85. doi:10.3109/01676830.2011.648797. PMID   22489850. S2CID   24169076.
  11. Rossomondo, R. M.; Carlton, W. H.; Trueblood, J. H.; Thomas, R. P. (1 November 1972). "A New Method of Evaluating Lacrimal Drainage". Archives of Ophthalmology. 88 (5): 523–525. doi:10.1001/archopht.1972.01000030525010. PMID   4634791.