Erythrulose reductase

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erythrulose reductase
Identifiers
EC no. 1.1.1.162
CAS no. 52064-49-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, erythrulose reductase (EC 1.1.1.162) is an enzyme that catalyzes the chemical reaction

 
 
 
H+
Erythrulose reductase
 
H+
 
 

The two substrates of this enzyme are D-threitol and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are D-erythrulose, reduced NADPH, and a proton. [1] [2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is erythritol:NADP+ oxidoreductase. This enzyme is also called D-erythrulose reductase.

References

  1. Enzyme 1.1.1.162 at KEGG Pathway Database.
  2. Uehara K, Tanimoto T, Sato H (February 1974). "Studies on D-tetrose metabolism. IV. Purification and some properties of D-erythrulose reductase from beef liver". J. Biochem. 75 (2). Tokyo: 333–45. doi:10.1093/oxfordjournals.jbchem.a130400. PMID   4152124.