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Threitol [1]
Systematic IUPAC name
Other names
(2R,3R)-Butane-1,2,3,4-tetraol (not recommended)
3D model (JSmol)
ECHA InfoCard 100.150.149
PubChem CID
Molar mass 122.12
Melting point 88 to 90 °C (190 to 194 °F; 361 to 363 K)
R-phrases (outdated) R36/37/38
S-phrases (outdated) S26 S36
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Threitol is a four-carbon sugar alcohol with the molecular formula C4H10O4. It is primarily used as an intermediate in the chemical synthesis of other compounds. It is the diastereomer of erythritol.


In living things, threitol is found in the edible fungus Armillaria mellea . [2] It serves as a cryoprotectant (antifreeze agent) in the Alaskan beetle Upis ceramboides . [3]

See also

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  1. Threitol at Sigma-Alrich
  2. Elks, J.; Ganellin, C. R. (1990). "Dictionary of Drugs". doi:10.1007/978-1-4757-2085-3. ISBN   978-1-4757-2087-7.Cite journal requires |journal= (help)
  3. Walters, K. R. Jr; Pan, Q.; Serianni, A. S.; Duman, J. G. (2009). "Cryoprotectant biosynthesis and the selective accumulation of threitol in the freeze-tolerant Alaskan beetle, Upis ceramboides". Journal of Biological Chemistry . 284 (25): 16822–16831. doi:10.1074/jbc.M109.013870. PMC   2719318 . PMID   19403530.