Haplogroup K2b (Y-DNA)

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Haplogroup K2b (P331)
Haplogroup K of Ydna haplotree.png
Possible time of originAbout 3,000 years younger than K-M9 40,000-50,000 years old
Possible place of originProbably East Asia [1] or Southeast Asia [2]
Ancestor K2
Descendants
  • K2b1 (previously known as MS) and;
  • Haplogroup P (K2b2; subclades include haplogroups Q and R).
Defining mutationsP331, CTS2019/M1205, PF5990/L405, PF5969, [3] [2]

Haplogroup K2b (P331), also known as MPS [3] is a human y-chromosome haplogroup that is thought to be less than 3,000 years younger than K, and less than 10,000 years younger than F, meaning it probably is around 50,000 years old, according to the age estimates of Tatiana Karafet et al. 2014. [2]

Contents

Basal paragroup K2b* has not been identified among living males but was found in Upper Paleolithic Tianyuan man from China. [4]

K2b1 (P397/P399) known previously as Haplogroup MS, and Haplogroup P (P-P295), also known as K2b2 are the only primary clades of K2b. The population geneticist Tatiana Karafet and other researchers (2014) point out that K2b1, its subclades and P* are virtually restricted geographically to South East Asia and Oceania. [2] Whereas, in a striking contrast, P1 (P-M45) and its primary subclades Q and R now make up "the most frequent haplogroup in Europe, the Americas, and Central Asia and South Asia". According to Karafet et al., the estimated dates for the branching of K, K2, K2b and P point to a "rapid diversification" within K2 "that likely occurred in Southeast Asia", with subsequent "westward expansions" of P*, P1, Q and R. [2]

According to geneticist Spencer Wells, haplogroup K originated in the Middle East or Central Asia, in the region of Iran or Pakistan. [5]

Phylogenetic structure

Distribution

Modern populations with living members of K2b1 all subclades), P* (P-P295*; K2b2*) and P2 (K2b2b) appear to be restricted to Oceania, South East Asia and Siberia.

Basal, un-mutated P1* (K2b2a*; P-M45*), in modern times, is distributed in isolated pockets, over an relatively wide area that includes Island South East Asia.

Some Negrito populations of South-East Asia carry next to noteworthy East Asian ancestry, very high levels of K2b at the subclade level. It is carried, for instance, by more than 83% of males among the Aeta (or Agta) people of the Philippines, in the form of K2b1 (60%), P* (P-P295*, a.k.a. K2b2*) and P2 (P-B253; K2b2b).

K2b1

K2b1 is found in 83% of males of Papua New Guinea, and up to 60% in the Aeta people of the Philippines. [2] It is also found among other Melanesian populations, as well as indigenous Australians, and at lower levels amongst Polynesians. [2] It is also found in the Melanesian populations of Indonesia.

Major studies of indigenous Australian Y-DNA, published in 2014 and 2015, suggest that about 29% of indigenous Australian males belong to subclades of K2b1. That is, up to 27% indigenous Australian males carry haplogroup S1a1a1 (S-P308; previously known as K2b1a1 or K-P308), [2] and one study found that approximately 2.0% – i.e. 0.9% (11 individuals) of the sample in a study in which 45% of the total was deemed to be non-indigenous – belonged to haplogroup M1 (M-M4; also known as M-M186 and known previously as haplogroup K2b1d1). All of these males carrying M1 were Torres Strait Islanders. [6] (The other Y-DNA haplogroups found were: basal K2* [K-M526], C1b2b [M347; previously Haplogroup C4], and basal C* [M130].)

PopulationK2b1 (including haplogroups M & S)
Papua New Guinea82.76%
Maori 03.82% (1.95% of those sampled, i.e. 49% of Maori males were deemed to have non-indigenous Y-DNA)
Fiji60.75%
Solomon Islands71.9%
French Polynesia08%
Vanuatu76.5%
New Caledonia
Guam33.3% (small sample size)
Samoa08.04%
Kiribati00% (small sample size)
Tonga20.69%
Micronesia FDR66.67%
Marshall Islands63.64%
American Samoa
Northern Mariana Islands
Palau61.5% (small sample size)
Cook Islands03.9%
Wallis and Futuna26%
Tuvalu36%
Nauru28.6% (small sample size)
Norfolk Island
Niue00% (small sample size)
Tokelau50% (small sample size)
Hawaii20% (small sample size from FTDNA)
Aboriginal Australians29% [6]
Timor25%
Aeta60%
Malaysia02.40% ( small sample size )
Flores35%
Sulawesi11.3%
Sulawesi00%
East Indonesia (Lesser Sunda Islands)25.9%
Java Indonesia00%
Bali Indonesia00.9%
Sumatra Indonesia00%
Borneo Indonesia05.8%
West Papua (Papua Province, Indonesia)52.6%
West Papua (Papua Province, Indonesia)82.6%
Sumba Indonesia25.2%
Chukkese people Micronesia76.5%
Pohnpeian people Micronesia70% (small sample size)

P (K2b2)

Apart from the basal paragroup P* (K2b2), it has only one subclade: P1 (M45), also known as K2b2a – which is also the parent of the major haplogroups Q (K2b2a1) and R (K2b2a2). [2]

P (K2b2) descendant haplogroups Q (K2b2a1) and R (K2b2a2) is widely distributed among males of Native American, Central Asian, South Asian and Siberian ancestry.

Basal P* (K2b2*)

P-P295* (sometimes known as "pre-P", before P-M45 was redesignated P1) is found among 28% of males among the Aeta, as well as in Timor at 10.8%, and one case may have been found in Papua New Guinea (Kaysar et al. 2006) although this has not been verified. [2]

PopulationRate of P* (%)Notes
Papua New Guinea0.69assumed from Kayser et al. 2006, i.e. one P* found
New Zealand0
Fiji0
Solomon Islands0
French Polynesia0
Vanuatu0
New Caledonia
Guam0
Samoa0
Kiribati
Tonga0
Federated States of Micronesia 0
Marshall Islands0
American Samoa
Northern Mariana Islands
Palau
Cook Islands0
Wallis and Futuna0
Tuvalu0
Nauru
Norfolk Island
Niue0small sample size
Tokelau0small sample size
Hawaii0small sample size from FTDNA
Australia0
Timor10.8
Aeta28
Filipino Austronesian0
Malay0
Flores0
Sulawesi0.6
East Indonesia0
Java Indonesia0
Bali Indonesia0
Sumatra Indonesia0
Borneo Indonesia0
West Papua Province0
Papua Province0
Sumba Indonesia3.2

P1 (K2b2a)

P1 (M45/PF5962), also known as K2b2a, is hundreds of times more common than P* (K2b2; PxM45), as it includes haplogroups Q and R, is estimated as being 14,300 years younger than K2b. [2]

Many ethnic groups with high frequencies of P1 are located in Central Asia and Siberia: 35.4% among Tuvans, 28.3% among Altaian Kizhi, [7] and 35% among Nivkh males.

Modern South Asian populations also feature P1 at low to moderate frequencies. [8] In South Asia it is most frequent among the Muslims of Manipur (33%), but this may be due to a very small sample size (nine individuals). Cases of P1 (M45) reported in South Asia may be unresolved cases or R2 or Q. [8]

Population group (with ethnolinguistic affiliation)PaperNPercentageSNPs Tested
Tuvinian (Turkic)Darenko 200511335.40P-M45
Nivkh (isolate)Lell 20011735P-M45
Altai-Kizhi (Altaians) (Turkic)Darenko 20059228.3P-M45
Todjin (Turkic)Darenko 20053622.2P-M45
Chukchi (Chukotkan)Lell 20012420.8P-M45
Koryak (Chukotkan)Lell 20012718.5P-M45
Yupik (Eskimo-Aleut)Lell 20013318.2P-M45
Uighur (Turkic)Xue 20067017.1P-M45
Kalmyk (Mongolic)Darenko 20056811.8P-M45
Turkmen (Turkic)Wells 20013010P-M45
Soyot (Turkic)Darenko 2005348.8P-M45
Uriankhai (Mongolic)Katoh 2004608.3P-M45
Khakas (Turkic)Darenko 2005537.6P-M45
Kazakh (Turkic)Wells 2001545.6P-M45
Uzbek (Turkic)Wells 20013665.5P-M45
Khasi-Khmuic (Austro-Asiatic)Reddy 20093535.40P-M45(xM173) §
Mundari (Austro-Asiatic)Reddy 20096410.90P-M45(xM173) §
Nicobarese (Mon-Khmer)Reddy 2009110.00P-M45(xM173) §
Southeast Asia ( Austro-Asiatic )Reddy 20092571.60P-M45(xM173) §
Garo (Tibeto-Burman)Reddy 2009711.40P-M45(xM173) §
India ( Tibeto-Burman )Reddy 20092263.10P-M45(xM173) §
East Asia (Tibeto-Burman)Reddy 20092140.00P-M45(xM173) §
Eastern India ( Indo-European )Reddy 20095418.50P-M45(xM173) §
Iran (Southern Talysh )Nasidze 2009504.00P-M45(xM124,xM173)
Azerbaijan (Northern Talysh )Nasidze 2009405.00P-M45(xM124,xM173)
Mazandarani (Iranian)Nasidze 2009504.00P-M45(xM124,xM173)
Gilaki (Iranian)Nasidze 2009500.00P-M45(xM124,xM173)
Tehran (Iranian)Nasidze 2004804.00P-M45(xM124,xM173)
Isfahan (Iranian)Nasidze 2004506.00P-M45(xM124,xM173)
Bakhtiari (Iranian)Nasidze 2008532.00P-M45(xM124,xM173)
Iranian Arabs (Arabic)Nasidze 2008472.00P-M45(xM124,xM173)
North Iran (Iranian)Regueiro 2006339.00P-M45(xM124,xM173)
South Iran (Iranian)Regueiro 20061173.00P-M45(xM124,xM173)
South Caucacus ( Georgian )Nasidze and Stoneking 2001773.00P-M45(xM124,xM173)
South Caucacus ( Armenian )Nasidze and Stoneking 20011002.00P-M45(xM124,xM173)
Hvar ( Croatian )Barać et al. 200314
Korčula ( Croatian )Barać et al. 20036

§ These may include members of haplogroup R2.

Population groupNP (xQ,xR)QRPaper
Count %Count %Count %
Gope 1616.4Sahoo 2006
Oriya Brahmin 2414.2Sahoo 2006
Mahishya 17317.6Sahoo 2006
Bhumij 15213.3Sahoo 2006
Saora 13323.1Sahoo 2006
Nepali 7228.6Sahoo 2006
Muslims of Manipur 9333.3Sahoo 2006
Himachal Pradesh Rajput 1516.7Sahoo 2006
Lambadi 18422.2Sahoo 2006
Gujarati Patel 9222.2Sahoo 2006
Katkari 1915.3Sahoo 2006
Madia Gond 1417.1Sahoo 2006
Kamma Chowdary 150016.71280Sahoo 2006

See also

Notes

Assuming B70 ky for the TMRCA of M168 chromosomes,10 we estimate the interval of time between the diversification of K-M9 and that of K-P331 to be <3 ky. This rapid diversification has also been assessed using whole Y-chromosome sequence data.22 In addition, we estimate the total time between the common ancestor of K-M9 and that of P-P295 to be <5 ky, and the time between the common ancestor P-P295 and that of P-P27 to be 12.3 ky (95% CI: 6.6–20 ky). [2]

Related Research Articles

<span class="mw-page-title-main">Haplogroup</span> Group of similar haplotypes

A haplotype is a group of alleles in an organism that are inherited together from a single parent, and a haplogroup is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation. More specifically, a haplotype is a combination of alleles at different chromosomal regions that are closely linked and that tend to be inherited together. As a haplogroup consists of similar haplotypes, it is usually possible to predict a haplogroup from haplotypes. Haplogroups pertain to a single line of descent. As such, membership of a haplogroup, by any individual, relies on a relatively small proportion of the genetic material possessed by that individual.

<span class="mw-page-title-main">Haplogroup J (Y-DNA)</span> Human Y-chromosome DNA haplogroup

Haplogroup J-M304, also known as J, is a human Y-chromosome DNA haplogroup. It is believed to have evolved in Western Asia. The clade spread from there during the Neolithic, primarily into North Africa, the Horn of Africa, the Socotra Archipelago, the Caucasus, Europe, Anatolia, Central Asia, South Asia, and Southeast Asia.

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<span class="mw-page-title-main">Haplogroup K-M9</span> Human Y chromosome DNA grouping indicating common ancestry

Haplogroup K or K-M9 is a genetic lineage within human Y-chromosome DNA haplogroup. A sublineage of haplogroup IJK, K-M9, and its descendant clades represent a geographically widespread and diverse haplogroup. The lineages have long been found among males on every continent except Antarctica.

<span class="mw-page-title-main">Haplogroup M-P256</span> Human Y chromosome DNA grouping common in New Guinea

Haplogroup M, also known as M-P256 and Haplogroup K2b1b is a Y-chromosome DNA haplogroup. M-P256 is a descendant haplogroup of Haplogroup K2b1, and is believed to have first appeared between 32,000 and 47,000 years ago.

<span class="mw-page-title-main">Haplogroup P (Y-DNA)</span> Human Y-chromosome DNA haplogroup

Haplogroup P also known as P-F5850 or K2b2 is a Y-chromosome DNA haplogroup in human genetics. P-F5850 is a branch of K2b, which is a branch of Haplogroup K2 (K-M526).

<span class="mw-page-title-main">Haplogroup Q-M242</span> Human Y chromosome DNA grouping common among Native Americans

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<span class="mw-page-title-main">Human Y-chromosome DNA haplogroup</span> Human DNA groupings

In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by mutations in the non-recombining portions of DNA from the male-specific Y chromosome. Many people within a haplogroup share similar numbers of short tandem repeats (STRs) and types of mutations called single-nucleotide polymorphisms (SNPs).

<span class="mw-page-title-main">Haplogroup R (Y-DNA)</span> Human Y-chromosome DNA haplogroup

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<span class="mw-page-title-main">Haplogroup DE</span> Human Y chromosome DNA grouping indicating common ancestry

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<span class="mw-page-title-main">Haplogroup CT</span> Human Y chromosome DNA grouping indicating common ancestry

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<span class="mw-page-title-main">Haplogroup K2</span> Human Y chromosome DNA grouping indicating common ancestry

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<span class="mw-page-title-main">Haplogroup S-M230</span> Human Y-chromosome DNA haplogroup

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Haplogroup IJK is a human Y-chromosome DNA haplogroup. IJK is a primary branch of the macrohaplogroup HIJK. Its direct descendants are haplogroup IJ and haplogroup K.

<span class="mw-page-title-main">Haplogroup R1b</span> Type of paternal lineage

Haplogroup R1b (R-M343), previously known as Hg1 and Eu18, is a human Y-chromosome haplogroup.

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<span class="mw-page-title-main">Haplogroup K2b1 (Y-DNA)</span> Human Y chromosome DNA grouping indicating common ancestry

Haplogroup K2b1, known sometimes as haplogroup MS, is a human Y-DNA haplogroup, defined by SNPs P397 and P399. It has a complex, diverse and not-yet fully understood internal structure; its downstream descendants include the major haplogroups Haplogroup M (P256) and Haplogroup S (M230).

Haplogroup P1, also known as P-M45 and K2b2a, is a Y-chromosome DNA haplogroup in human genetics. Defined by the SNPs M45 and PF5962, P1 is a primary branch (subclade) of P.

<span class="mw-page-title-main">Haplogroup K2a (Y-DNA)</span> Human Y-chromosome DNA haplogroup

Haplogroup K2a is a human Y-chromosome DNA haplogroup. K2a is a primary subclade of haplogroup K2 (M526), which in turn is a primary descendant of haplogroup K (M9). Its sole primary descendant is haplogroup K-M2313.

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