Hydrocotyle sibthorpioides

Last updated

Lawn marshpennywort
Hydrocotyle sibthorpioides.JPG
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Apiales
Family: Araliaceae
Genus: Hydrocotyle
Species:
H. sibthorpioides
Binomial name
Hydrocotyle sibthorpioides
Synonyms [1]
  • Chondrocarpus sibthorpioidesSweet
  • Hydrocotyle keelungensisLiu, Chao & Chuang
  • Hydrocotyle monticolaHook. f.
  • Hydrocotyle rotundifoliaRoxb. ex DC.
  • Hydrocotyle tenellaBuch.-Ham. ex D. Don
  • Hydrocotyle tuberiferaOhwi

Hydrocotyle sibthorpioides is a small plant native to southeastern Asia. It is also referred to as lawn marshpennywort. [2] It is a dicot, traditionally placed in the family Apiaceae, but more recently suggested to belong in the Araliaceae. [3] It grows in abundance when the conditions are right. Hydrocotyle sibthorpioides originated in southeastern Asia, but is slowly spreading in the United States, along with other places around the world. It can grow in a wide variety of habitats. It has been used for medicinal purposes in Asia and is also common in the aquarium trade.

Contents

Description

The leaf width ranges from 0.5 to 2 cm. The plant has a moderate growth rate [4] and produces small flowers. The flowers are a faint yellow with a hint of purple. [5] Flower clusters are simple and flat topped or rounded. There are inconspicuous involucral bracts at the base of each flower and indistinct sepals. The leaves are simple, with a small leafy outgrowth at the base, and kidney-shaped to round. Leaf edges are scalloped. The leaves are broad and alternate. The peltate leaves are often described as egg-shaped; all of the leaves are hairless and they often have five to seven shallow lobes around the edge. Fruits are flat and break in half when the plant reaches maturity. Once the fruit has broken open, there is one seed on each side. [6] The fruits are elliptical to round with thin ridges and no oil tubes (vitta), which is characteristic in the fruit of umbelliferous plants. [7]

Taxonomy

Hydrocotyle sibthorpioides is traditionally treated within the family Apiaceae, [8] although recent results place it in the Araliaceae. [3] A moleculary phylogeny shows H. sibthorpioides to be closely related to H. americana , H. bonariensis , H. bowlesioides , H. hirsute , and H. umbellata , among others. [8]

Distribution and habitat

Hydrocoytle sibthorpioides is most common in southeastern Asia. Although it is native to Asia, there are parts of the United States where this plant thrives as an introduced species, particularly in the eastern US and some areas in California. [9] Recently, it has been reported to flourish in southeast Australia, where it occurs in Brisbane and Sydney, is native to Western Australia. [10] This species is able to grow in a wide variety of habitats, from dry areas to locations that are occasionally submerged. It can also be found between sidewalk cracks, and is increasingly occurring as a lawn weed. [11]

Culture

For the plant to reach its full growth it must have full sunlight. [9] It can tolerate temperatures between 10 and 30°C, but grows best when the temperature stays between 20 and 28°C. It has a soil pH preference of 5 to 7. Propagation of this plant is mostly by cuttings. [12]

Conservation status

The conservation status for H. sibthorpioides is of least concern; it continues to grow and spread throughout the United States along with other regions of the world such as Australia. [13]

Chemical composition

Phytochemical investigations identified and isolated 50 phytoconstituents from the plant, of which asiaticoside and madecasoside were the chief constituents. Phytoconstituents isolated were camphene, genistein, hydrocosisaponin A-F, hydrocotyloside I-VII, isorhamnetin, l-sesamin, ocimene, phytol, quercetin, hyperoside, quercetin 3-(6-caffeoylgalactoside), stigmasterol, stigmasterol isomers, trans-β-farnesene, udosaponin B, α-humulene, α-pinene, β-caryophyllene, and β-pinene. Other compounds identified by HPLC analysis are 2-ethylacridine, 2-methyl-3-O-tolyl-6-hydroxy-4(3H)-quinazolinone, 3-(4-(hydroxymethyl)phenyl)-2-ethylquinazolin-4(3H)-one, demecolcine, 9,10,10-trimethyl-9,10-dihydroanthracene, rosmarinic acid, chlorogenic acid, catechin, epicatechin, quercetin, biochanin A, rutin, gallic acid, ferulic acid, caffeic acid, ascorbic acid, and α-tocopherol. [14]


Use in traditional medicine

Many tribes in the world use H. sibthorpioides to treat fever, edoema, dysentery, rheumatalgia, whooping cough, jaundice, throat discomfort, psoriasis, herpes zoster infection, hepatitis-B infection, calming pain, dysmenorrhoea, and carbunculosis. [15] In Assam, it is also employed as a hepatoprotective agent, a brain tonic, and a detoxifying agent. [16] Bengali villagers use the entire plant for bone fractures. [17] Extracts of this plant have been found to be free from toxicity up to a dose of 2000 mg/kg in rats. [18]

Toxicity

The phytoconstituents of H. sibthorpioides have shown a wide range of therapeutic utility, although pharmacological use is only justified if it has a satisfactory safety profile. There is no indication that the plant or its extracts have ever been tested in a clinical experiment. Following OECD standards 425, Hazarika et al. (2019) conducted a preclinical acute toxicity investigation on several extracts of H. sibthorpioides using albino rats, and found that the LD50 was larger than 2000 mg/kg of body weight. [19]

Related Research Articles

<span class="mw-page-title-main">Silibinin</span> Chemical compound

Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others. Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. Silibinin is used in pure forms as a medication, and more frequently as an active ingredient in milk thistle–derived herbal supplements.

<span class="mw-page-title-main">Quercetin</span> Chemical compound

Quercetin is a plant flavonol from the flavonoid group of polyphenols. It is found in many fruits, vegetables, leaves, seeds, and grains; capers, red onions, and kale are common foods containing appreciable amounts of it. It has a bitter flavor and is used as an ingredient in dietary supplements, beverages, and foods.

<span class="mw-page-title-main">Punicalagin</span> Chemical compound

Punicalagin (Pyuni-cala-jen) is an ellagitannin, a type of phenolic compound. It is found as alpha and beta isomers in pomegranates, Terminalia catappa, Terminalia myriocarpa, and in Combretum molle, the velvet bushwillow, a plant species found in South Africa. These three genera are all Myrtales and the last two are both Combretaceae.

<i>Plantago asiatica</i> Species of flowering plant in the plantain family Plantaginaceae

Plantago asiatica, is a self-fertile, perennial flowering plant of genus Plantago. The plant is native to East Asia. It grows really well in disturbed areas like roadsides or even dirt roads. It is valued for its use in folk medicine and it also can be used in cooking.

<span class="mw-page-title-main">Achyrocline saturejoides</span> Species of flowering plant

Achyrocline satureioides, commonly known as macela or marcela, is a species of plant in the family Asteraceae. It is native to South America, from Argentina to Colombia to Guyana. A semi-annual herbaceous plant reaching about a meter tall, it has simple, narrow green leaves with serrated edges. It produces yellow flowers in racemes around Easter.

<i>Adenanthera pavonina</i> Species of legume

Adenanthera pavonina is a perennial and non-climbing species of leguminous tree. Its uses include food and drink, traditional medicine, and timber.

<i>Kaempferia galanga</i> Species of flowering plant

Kaempferia galanga, commonly known as kencur, aromatic ginger, sand ginger, cutcherry, is a monocotyledonous plant in the ginger family, and one of four plants called galangal. It is found primarily in open areas in Indonesia, southern China, Taiwan, Cambodia, and India, but is also widely cultivated throughout Southeast Asia.

<i>Barringtonia acutangula</i> Species of plant

Barringtonia acutangula is a species of Barringtonia native to coastal wetlands in southern Asia and northern Australasia, from Afghanistan east to the Philippines, Queensland and the Northern Territory. Common names include freshwater mangrove, itchytree and mango-pine.

<span class="mw-page-title-main">DU145</span>

DU145 (DU-145) is a human prostate cancer cell line. DU145, PC3, and LNCaP are considered to be the standard prostate cancer cell lines used in therapeutic research.

<i>Alstonia scholaris</i> Species of tree

Alstonia scholaris, commonly called blackboard tree, scholar tree, milkwood or devil's tree in English, is an evergreen tropical tree in the Dogbane Family (Apocynaceae). It is native to southern China, tropical Asia and Australasia, where it is a common ornamental plant. It is a toxic plant, but is used traditionally for myriad diseases and complaints.

<i>Vitex negundo</i> Species of flowering plant

Vitex negundo, commonly known as the Chinese chaste tree, five-leaved chaste tree, or horseshoe vitex, or nisinda is a large aromatic shrub with quadrangular, densely whitish, tomentose branchlets. It is widely used in folk medicine, particularly in South and Southeast Asia.

<span class="mw-page-title-main">Barakol</span> Chemical compound

Barakol is a compound found in the plant Senna siamea, which is used in traditional herbal medicine. It has sedative and anxiolytic effects. There are contradictory pharmacological research findings concerning the toxicity of Cassia siamea and the active ingredient Barakol. One pharmacological study has shown an hepatoxic effect of Barakol while another study did not show any toxic effect at a daily dosage intake. Further research is needed to verify whether there are toxic effects of Barakol or not.

<span class="mw-page-title-main">Lupeol</span> Chemical compound

Lupeol is a pharmacologically active pentacyclic triterpenoid. It has several potential medicinal properties, like anticancer and anti-inflammatory activity.

<span class="mw-page-title-main">Bakuchiol</span> Chemical compound

Bakuchiol is a meroterpenoid in the class terpenophenol.

<span class="mw-page-title-main">Chrysophanol</span> Chemical compound

Chrysophanol, also known as chrysophanic acid, is a fungal isolate and a natural anthraquinone. It is a C-3 methyl substituted chrysazin of the trihydroxyanthraquinone family.

<i>Echeveria gibbiflora</i> Species of succulent

Echeveria gibbiflora is a species of flowering plant in the family Crassulaceae. It was described by Swiss botanist Augustin Pyramus de Candolle in 1828. It occurs in Mexico and Guatemala.

<i>Hypericum oblongifolium</i> Species of flowering plant

Hypericum oblongifolium, known as Pendant St. John's wort, is a species of flowering plant in Hypericumsect. Ascyreia.

<span class="mw-page-title-main">Black radish</span> Species of flowering plant

The black radish is a root vegetable of the family Brassicaceae and is a variety of winter radish. It is also called Black Spanish radish or Erfurter radish.

<span class="mw-page-title-main">Suzanne Urverg-Ratsimamanga</span> French-Malagasy Ashkenazi Jews physician and biochemist (1928-2016)

Suzanne Urverg-Ratsimamanga was a French-Malagasy Ashkenazi Jewish physician and biochemist. She was married to Albert Rakoto Ratsimamanga, with whom she founded the Malagasy Institute of Applied Research.

<i>Hypericum origanifolium</i> Species of flowering plant

Hypericum origanifolium is a species of flowering plant in the family Hypericaceae. It is native to Turkey, the Caucasus, and northwestern Syria. The species can be found in dry, often rocky, soil and on cliff slopes and ledges.

References

  1. The Plant List: A Working List of All Plant Species , retrieved 17 July 2017
  2. USDA, NRCS (n.d.). "Hydrocotyle sibthorpioides". The PLANTS Database (plants.usda.gov). Greensboro, North Carolina: National Plant Data Team. Retrieved 8 December 2016.
  3. 1 2 Chandler, G. T.; Plunkett, G. M. (2004-02-01). "Evolution in Apiales: nuclear and chloroplast markers together in (almost) perfect harmony". Botanical Journal of the Linnean Society. 144 (2): 123–147. doi: 10.1111/j.1095-8339.2003.00247.x . ISSN   0024-4074.
  4. Gross, Tom. "Hydrocotyle sibthorpioides". PlantFinder. aquaticplantcentral.com. Archived from the original on 5 February 2020. Retrieved 7 November 2016.
  5. "Hydrocotyle sibthorpioides". Yarra Ranges. Retrieved 7 November 2016.
  6. "Pennywort (Hydrocotyle sp.)". UCIPM. Retrieved 7 November 2016.
  7. Flora of China. "Hydrocotyle Linn.". Family List. Retrieved 2008-04-25.
  8. 1 2 "Hydrocotyle sibthorpioides Lam". ITIS Report. ITIS. Retrieved 7 November 2016.
  9. 1 2 "Hydrocotyle sibthorpioides Lam. Lawn Marshpennywort". USDA plants. Retrieved 7 November 2016.
  10. "Hydrocotyle sibthorpioides Lam". Atlas of Living Australia. Retrieved 7 November 2016.
  11. Weakley, Alan. "Flora of the Southern and Mid Atlantic States". UNC Herbarium Weakley Flora. Archived from the original on 6 October 2018. Retrieved 7 November 2016.
  12. "Hydrocotyle sibthorpioides". Flowgrow- Wir Lassen es Wachsen. Retrieved 7 November 2016.
  13. "Hydrocotyle sibthorpioides- Lam". Plants for a Future. Retrieved 7 November 2016.
  14. Hazarika, Iswar; Mukundan, Geetha K.; Sundari, P. Sivakami; Laloo, Damiki (April 2021). "Journey of Hydrocotyle sibthorpioides Lam.: From traditional utilization to modern therapeutics—A review". Phytotherapy Research. 35 (4): 1847–1871. doi:10.1002/ptr.6924. ISSN   0951-418X. S2CID   226241205.
  15. Hazarika, Iswar; Mukundan, Geetha K.; Sundari, P. Sivakami; Laloo, Damiki (April 2021). "Journey of Hydrocotyle sibthorpioides Lam.: From traditional utilization to modern therapeutics—A review". Phytotherapy Research. 35 (4): 1847–1871. doi:10.1002/ptr.6924. ISSN   0951-418X. PMID   33140507. S2CID   226241205.
  16. Hazarika, Iswar; Mukundan, Geetha K.; Sundari, P. Sivakami; Laloo, Damiki (April 2021). "Journey of Hydrocotyle sibthorpioides Lam.: From traditional utilization to modern therapeutics—A review". Phytotherapy Research. 35 (4): 1847–1871. doi:10.1002/ptr.6924. ISSN   0951-418X. PMID   33140507. S2CID   226241205.
  17. Rahmatullah, Mohammed (2010). "A Comparative Analysis of Medicinal Plants used by Folk Medicinal Healers in Villages Adjoining the Ghaghut, Bengali, Padma Rivers of Bangladesh". American- Eurasian Journal of Sustainable Agriculture (4): 70–85.
  18. Hazarika, Iswar; Geetha, K.M.; Sundari, P. Sivakami; Madhu, Divya (2019). "Acute oral toxicity evaluation of extracts of Hydrocotyle sibthorpioides in wister albino rats as per OECD 425 TG". Toxicology Reports. 6: 321–328. doi:10.1016/j.toxrep.2019.04.001. PMC   6460325 . PMID   31011541.
  19. Hazarika, Iswar; Geetha, K.M.; Sundari, P. Sivakami; Madhu, Divya (2019). "Acute oral toxicity evaluation of extracts of Hydrocotyle sibthorpioides in Wister albino rats as per OECD 425 TG". Toxicology Reports. 6: 321–328. doi: 10.1016/j.toxrep.2019.04.001 . PMC   6460325 . PMID   31011541.