Lawn marshpennywort | |
---|---|
Scientific classification | |
Kingdom: | Plantae |
Clade: | Tracheophytes |
Clade: | Angiosperms |
Clade: | Eudicots |
Clade: | Asterids |
Order: | Apiales |
Family: | Araliaceae |
Genus: | Hydrocotyle |
Species: | H. sibthorpioides |
Binomial name | |
Hydrocotyle sibthorpioides | |
Synonyms [1] | |
|
Hydrocotyle sibthorpioides is a small plant native to southeastern Asia. It is also referred to as lawn marshpennywort. [2] It is a dicot, traditionally placed in the family Apiaceae, but more recently suggested to belong in the Araliaceae. [3] It grows in abundance when the conditions are right. Hydrocotyle sibthorpioides originated in southeastern Asia, but is slowly spreading in the United States, along with other places around the world. It can grow in a wide variety of habitats. It has been used for medicinal purposes in Asia and is also common in the aquarium trade.
The leaf width ranges from 0.5 to 2 cm. The plant has a moderate growth rate [4] and produces small flowers. The flowers are a faint yellow with a hint of purple. [5] Flower clusters are simple and flat topped or rounded. There are inconspicuous involucral bracts at the base of each flower and indistinct sepals. The leaves are simple, with a small leafy outgrowth at the base, and kidney-shaped to round. Leaf edges are scalloped. The leaves are broad and alternate. The peltate leaves are often described as egg-shaped; all of the leaves are hairless and they often have five to seven shallow lobes around the edge. Fruits are flat and break in half when the plant reaches maturity. Once the fruit has broken open, there is one seed on each side. [6] The fruits are elliptical to round with thin ridges and no oil tubes (vitta), which is characteristic in the fruit of umbelliferous plants. [7]
Hydrocotyle sibthorpioides is traditionally treated within the family Apiaceae, [8] although recent results place it in the Araliaceae. [3] A moleculary phylogeny shows H. sibthorpioides to be closely related to H. americana , H. bonariensis , H. bowlesioides , H. hirsute , and H. umbellata , among others. [8]
Hydrocoytle sibthorpioides is most common in southeastern Asia. Although it is native to Asia, there are parts of the United States where this plant thrives as an introduced species, particularly in the eastern US and some areas in California. [9] Recently, it has been reported to flourish in southeast Australia, where it occurs in Brisbane and Sydney, is native to Western Australia. [10] This species is able to grow in a wide variety of habitats, from dry areas to locations that are occasionally submerged. It can also be found between sidewalk cracks, and is increasingly occurring as a lawn weed. [11]
For the plant to reach its full growth it must have full sunlight. [9] It can tolerate temperatures between 10 and 30°C, but grows best when the temperature stays between 20 and 28°C. It has a soil pH preference of 5 to 7. Propagation of this plant is mostly by cuttings. [12]
The conservation status for H. sibthorpioides is of least concern; it continues to grow and spread throughout the United States along with other regions of the world such as Australia. [13]
Phytochemical investigations identified and isolated 50 phytoconstituents from the plant, of which asiaticoside and madecasoside were the chief constituents. Phytoconstituents isolated were camphene, genistein, hydrocosisaponin A-F, hydrocotyloside I-VII, isorhamnetin, l-sesamin, ocimene, phytol, quercetin, hyperoside, quercetin 3-(6-caffeoylgalactoside), stigmasterol, stigmasterol isomers, trans-β-farnesene, udosaponin B, α-humulene, α-pinene, β-caryophyllene, and β-pinene. Other compounds identified by HPLC analysis are 2-ethylacridine, 2-methyl-3-O-tolyl-6-hydroxy-4(3H)-quinazolinone, 3-(4-(hydroxymethyl)phenyl)-2-ethylquinazolin-4(3H)-one, demecolcine, 9,10,10-trimethyl-9,10-dihydroanthracene, rosmarinic acid, chlorogenic acid, catechin, epicatechin, quercetin, biochanin A, rutin, gallic acid, ferulic acid, caffeic acid, ascorbic acid, and α-tocopherol. [14]
Many tribes in the world use H. sibthorpioides to treat fever, edoema, dysentery, rheumatalgia, whooping cough, jaundice, throat discomfort, psoriasis, herpes zoster infection, hepatitis-B infection, calming pain, dysmenorrhoea, and carbunculosis. [15] In Assam, it is also employed as a hepatoprotective agent, a brain tonic, and a detoxifying agent. [16] Bengali villagers use the entire plant for bone fractures. [17] Extracts of this plant have been found to be free from toxicity up to a dose of 2000 mg/kg in rats. [18]
The phytoconstituents of H. sibthorpioides have shown a wide range of therapeutic utility, although pharmacological use is only justified if it has a satisfactory safety profile. There is no indication that the plant or its extracts have ever been tested in a clinical experiment. Following OECD standards 425, Hazarika et al. (2019) conducted a preclinical acute toxicity investigation on several extracts of H. sibthorpioides using albino rats, and found that the LD50 was larger than 2000 mg/kg of body weight. [19]
Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others. Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. Silibinin is used in pure forms as a medication, and more frequently as an active ingredient in milk thistle–derived herbal supplements.
Quercetin is a plant flavonol from the flavonoid group of polyphenols. It is found in many fruits, vegetables, leaves, seeds, and grains; capers, red onions, and kale are common foods containing appreciable amounts of it. It has a bitter flavor and is used as an ingredient in dietary supplements, beverages, and foods.
Punicalagin (Pyuni-cala-jen) is an ellagitannin, a type of phenolic compound. It is found as alpha and beta isomers in pomegranates, Terminalia catappa, Terminalia myriocarpa, and in Combretum molle, the velvet bushwillow, a plant species found in South Africa. These three genera are all Myrtales and the last two are both Combretaceae.
Plantago asiatica, is a self-fertile, perennial flowering plant of genus Plantago. The plant is native to East Asia. It grows really well in disturbed areas like roadsides or even dirt roads. It is valued for its use in folk medicine and it also can be used in cooking.
Achyrocline satureioides, commonly known as macela or marcela, is a species of plant in the family Asteraceae. It is native to South America, from Argentina to Colombia to Guyana. A semi-annual herbaceous plant reaching about a meter tall, it has simple, narrow green leaves with serrated edges. It produces yellow flowers in racemes around Easter.
Adenanthera pavonina is a perennial and non-climbing species of leguminous tree. Its uses include food and drink, traditional medicine, and timber.
Kaempferia galanga, commonly known as kencur, aromatic ginger, sand ginger, cutcherry, is a monocotyledonous plant in the ginger family, and one of four plants called galangal. It is found primarily in open areas in Indonesia, southern China, Taiwan, Cambodia, and India, but is also widely cultivated throughout Southeast Asia.
Barringtonia acutangula is a species of Barringtonia native to coastal wetlands in southern Asia and northern Australasia, from Afghanistan east to the Philippines, Queensland and the Northern Territory. Common names include freshwater mangrove, itchytree and mango-pine.
DU145 (DU-145) is a human prostate cancer cell line. DU145, PC3, and LNCaP are considered to be the standard prostate cancer cell lines used in therapeutic research.
Alstonia scholaris, commonly called blackboard tree, scholar tree, milkwood or devil's tree in English, is an evergreen tropical tree in the Dogbane Family (Apocynaceae). It is native to southern China, tropical Asia and Australasia, where it is a common ornamental plant. It is a toxic plant, but is used traditionally for myriad diseases and complaints.
Vitex negundo, commonly known as the Chinese chaste tree, five-leaved chaste tree, or horseshoe vitex, or nisinda is a large aromatic shrub with quadrangular, densely whitish, tomentose branchlets. It is widely used in folk medicine, particularly in South and Southeast Asia.
Barakol is a compound found in the plant Senna siamea, which is used in traditional herbal medicine. It has sedative and anxiolytic effects. There are contradictory pharmacological research findings concerning the toxicity of Cassia siamea and the active ingredient Barakol. One pharmacological study has shown an hepatoxic effect of Barakol while another study did not show any toxic effect at a daily dosage intake. Further research is needed to verify whether there are toxic effects of Barakol or not.
Lupeol is a pharmacologically active pentacyclic triterpenoid. It has several potential medicinal properties, like anticancer and anti-inflammatory activity.
Bakuchiol is a meroterpenoid in the class terpenophenol.
Chrysophanol, also known as chrysophanic acid, is a fungal isolate and a natural anthraquinone. It is a C-3 methyl substituted chrysazin of the trihydroxyanthraquinone family.
Echeveria gibbiflora is a species of flowering plant in the family Crassulaceae. It was described by Swiss botanist Augustin Pyramus de Candolle in 1828. It occurs in Mexico and Guatemala.
Hypericum oblongifolium, known as Pendant St. John's wort, is a species of flowering plant in Hypericumsect. Ascyreia.
The black radish is a root vegetable of the family Brassicaceae and is a variety of winter radish. It is also called Black Spanish radish or Erfurter radish.
Suzanne Urverg-Ratsimamanga was a French-Malagasy Ashkenazi Jewish physician and biochemist. She was married to Albert Rakoto Ratsimamanga, with whom she founded the Malagasy Institute of Applied Research.
Hypericum origanifolium is a species of flowering plant in the family Hypericaceae. It is native to Turkey, the Caucasus, and northwestern Syria. The species can be found in dry, often rocky, soil and on cliff slopes and ledges.