Isoeugenol synthase

Isoeugenol synthase
Identifiers
EC no.	1.1.1.319
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Isoeugenol synthase (EC 1.1.1.319, IGS1, t-anol/isoeugenol synthase 1) is an enzyme with systematic name eugenol:NADP⁺ oxidoreductase (coniferyl acetate reducing). ^{[1] [2] [3]} This enzyme catalyses the following chemical reaction. ^{[4] [5]}

coniferyl acetate

+ NADPH

 

 

H⁺

 

H⁺

 

 

isoeugenol

+ CH₃CO₂H + NADP⁺

 

The usual substrate is coniferyl acetate which gives isoeugenol. ^{[6] [7]}

References

1. Koeduka T, Fridman E, Gang DR, Vassão DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E (June 2006). "Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester". Proceedings of the National Academy of Sciences of the United States of America. 103 (26): 10128–33. doi: 10.1073/pnas.0603732103 . PMC   1502517 . PMID   16782809.
2. Koeduka T, Louie GV, Orlova I, Kish CM, Ibdah M, Wilkerson CG, Bowman ME, Baiga TJ, Noel JP, Dudareva N, Pichersky E (May 2008). "The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages". The Plant Journal. 54 (3): 362–74. doi:10.1111/j.1365-313X.2008.03412.x. PMC   2741023 . PMID   18208524.
3. Koeduka T, Baiga TJ, Noel JP, Pichersky E (January 2009). "Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain". Plant Physiology. 149 (1): 384–94. doi:10.1104/pp.108.128066. PMC   2613694 . PMID   18987218.
4. Gupta AK, Schauvinhold I, Pichersky E, Schiestl FP (December 2014). "Eugenol synthase genes in floral scent variation in Gymnadenia species" (PDF). Functional & Integrative Genomics. 14 (4): 779–88. doi:10.1007/s10142-014-0397-9. hdl: 20.500.11850/91540 . PMID   25239559. S2CID   17207240.
5. Enzyme 1.1.1.319 at KEGG Pathway Database.
6. Vogt, Thomas (2010). "Phenylpropanoid Biosynthesis". Molecular Plant . 3 (1): 2–20. doi: 10.1093/mp/ssp106 . PMID   20035037. S2CID   39503278.
7. Dexter, Richard; Qualley, Anthony; Kish, Christine M.; Ma, Choong Je; Koeduka, Takao; Nagegowda, Dinesh A.; Dudareva, Natalia; Pichersky, Eran; Clark, David (2006-12-07). "Characterization of a petunia acetyltransferase involved in the biosynthesis of the floral volatile isoeugenol". The Plant Journal . 49 (2): 265–275. doi:10.1111/j.1365-313x.2006.02954.x. hdl: 2027.42/74478 . PMID   17241449. S2CID   6714361.

External links

• Isoeugenol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)