Midget cell | |
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Details | |
Part of | Retina of eye |
System | Visual system |
Identifiers | |
FMA | 62360 |
Anatomical terminology |
A midget cell, sometimes called a P cell or P ganglion cell, is one type of retinal ganglion cell (RGC). Midget cells originate in the ganglion cell layer of the retina, and project to the parvocellular layers of the lateral geniculate nucleus (LGN). The axons of midget cells travel through the optic nerve and optic tract, ultimately synapsing with parvocellular cells in the LGN. These cells are known as midget retinal ganglion cells due to the small sizes of their dendritic trees and cell bodies. About 80% of RGCs are midget cells. They receive inputs from relatively few rods and cones. In many cases, they are connected to midget bipolar cells, which are linked to one cone each. [1]
These neurons show roughly circular receptive fields with antagonistic center and surround; this property is known as spatial opponency and these neurons are typically divided into ON- or OFF-center, depending on whether they are excited or inhibited by photons falling on the center of their receptive fields. [2] Most of these cells are chromatically opponent, meaning that long- and medium-wavelength visible light (commonly approximated to red and green, respectively) exert opposing effects on the center and the surround. [2] For instance, a chromatically opponent L-ON (Long ON) midget cell would be excited (and more likely to spike action potentials) if light of long wavelength falls on the cone or cones in the center of its receptive field but would be inhibited by medium-wavelength light falling on the surround of its receptive field. [2] However, not all midget cells are chromatically opponent. [2]
They have slow conduction velocity and are very responsive to high temporal frequencies (i.e. rapidly and low spatial frequencies). [3]
The retina is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerve impulses along the optic nerve to the visual cortex to create visual perception. The retina serves a function which is in many ways analogous to that of the film or image sensor in a camera.
Color vision, a feature of visual perception, is an ability to perceive differences between light composed of different frequencies independently of light intensity.
The visual system is the physiological basis of visual perception. The system detects, transduces and interprets information concerning light within the visible range to construct an image and build a mental model of the surrounding environment. The visual system is associated with the eye and functionally divided into the optical system and the neural system.
In neuroanatomy, the lateral geniculate nucleus is a structure in the thalamus and a key component of the mammalian visual pathway. It is a small, ovoid, ventral projection of the thalamus where the thalamus connects with the optic nerve. There are two LGNs, one on the left and another on the right side of the thalamus. In humans, both LGNs have six layers of neurons alternating with optic fibers.
A photoreceptor cell is a specialized type of neuroepithelial cell found in the retina that is capable of visual phototransduction. The great biological importance of photoreceptors is that they convert light into signals that can stimulate biological processes. To be more specific, photoreceptor proteins in the cell absorb photons, triggering a change in the cell's membrane potential.
The fovea centralis is a small, central pit composed of closely packed cones in the eye. It is located in the center of the macula lutea of the retina.
A retinal ganglion cell (RGC) is a type of neuron located near the inner surface of the retina of the eye. It receives visual information from photoreceptors via two intermediate neuron types: bipolar cells and retina amacrine cells. Retina amacrine cells, particularly narrow field cells, are important for creating functional subunits within the ganglion cell layer and making it so that ganglion cells can observe a small dot moving a small distance. Retinal ganglion cells collectively transmit image-forming and non-image forming visual information from the retina in the form of action potential to several regions in the thalamus, hypothalamus, and mesencephalon, or midbrain.
The receptive field, or sensory space, is a delimited medium where some physiological stimuli can evoke a sensory neuronal response in specific organisms.
In neuroscience, parvocellular cells, also called P-cells, are neurons located within the parvocellular layers of the lateral geniculate nucleus (LGN) of the thalamus. Their name comes from Latin parvus 'small', due to the small size of the cell compared to the larger magnocellular cells. Phylogenetically, parvocellular neurons are more modern than magnocellular ones.
Magnocellular cells, also called M-cells, are neurons located within the magnocellular layer of the lateral geniculate nucleus of the thalamus. The cells are part of the visual system. They are termed "magnocellular" since they are characterized by their relatively large size compared to parvocellular cells.
As a part of the retina, bipolar cells exist between photoreceptors and ganglion cells. They act, directly or indirectly, to transmit signals from the photoreceptors to the ganglion cells.
The opponent process is a color theory that states that the human visual system interprets information about color by processing signals from photoreceptor cells in an antagonistic manner. The opponent-process theory suggests that there are three opponent channels, each comprising an opposing color pair: red versus green, blue versus yellow, and black versus white (luminance). The theory was first proposed in 1892 by the German physiologist Ewald Hering.
Visual phototransduction is the sensory transduction process of the visual system by which light is detected by photoreceptor cells in the vertebrate retina. A photon is absorbed by a retinal chromophore, which initiates a signal cascade through several intermediate cells, then through the retinal ganglion cells (RGCs) comprising the optic nerve.
In neuroscience, koniocellular cells, also called K-cells, are relatively small neurons located in the koniocellular layer of the lateral geniculate nucleus (LGN) within the thalamus of primates, including humans. The term 'koniocellular' is derived from Greek konio 'dust, poison'.
Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or melanopsin-containing retinal ganglion cells (mRGCs), are a type of neuron in the retina of the mammalian eye. The presence of an additional photoreceptor was first suspected in 1927 when mice lacking rods and cones still responded to changing light levels through pupil constriction; this suggested that rods and cones are not the only light-sensitive tissue. However, it was unclear whether this light sensitivity arose from an additional retinal photoreceptor or elsewhere in the body. Recent research has shown that these retinal ganglion cells, unlike other retinal ganglion cells, are intrinsically photosensitive due to the presence of melanopsin, a light-sensitive protein. Therefore, they constitute a third class of photoreceptors, in addition to rod and cone cells.
In neuroanatomy, the retinohypothalamic tract (RHT) is a photic neural input pathway involved in the circadian rhythms of mammals. The origin of the retinohypothalamic tract is the intrinsically photosensitive retinal ganglion cells (ipRGC), which contain the photopigment melanopsin. The axons of the ipRGCs belonging to the retinohypothalamic tract project directly, monosynaptically, to the suprachiasmatic nuclei (SCN) via the optic nerve and the optic chiasm. The suprachiasmatic nuclei receive and interpret information on environmental light, dark and day length, important in the entrainment of the "body clock". They can coordinate peripheral "clocks" and direct the pineal gland to secrete the hormone melatonin.
Mammals normally have a pair of eyes. Although mammalian vision is not so excellent as bird vision, it is at least dichromatic for most of mammalian species, with certain families possessing a trichromatic color perception.
A parasol cell, sometimes called an M cell or M ganglion cell, is one type of retinal ganglion cell (RGC) located in the ganglion cell layer of the retina. These cells project to magnocellular cells in the lateral geniculate nucleus (LGN) as part of the magnocellular pathway in the visual system. They have large cell bodies as well as extensive branching dendrite networks and as such have large receptive fields. Relative to other RGCs, they have fast conduction velocities. While they do show clear center-surround antagonism, they receive no information about color. Parasol ganglion cells contribute information about the motion and depth of objects to the visual system.
Bistratified cell or bistratified ganglion cell can refer to either of two kinds of retinal ganglion cells whose cell body is located in the ganglion cell layer of the retina: