Omega-hydroxydecanoate dehydrogenase

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omega-hydroxydecanoate dehydrogenase
Identifiers
EC no. 1.1.1.66
CAS no. 9028-65-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, omega-hydroxydecanoate dehydrogenase (EC 1.1.1.66) is an enzyme that catalyzes the chemical reaction

 
 
 
H+
Omega-hydroxydecanoate dehydrogenase
 
H+
 
 

The two substrates of this enzyme are 10-hydroxydecanoic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 10-oxodecanoic acid, reduced NADH, and a proton. [1] [2] [3]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-hydroxydecanoate:NAD+ 10-oxidoreductase.

References

  1. Enzyme 1.1.1.66 at KEGG Pathway Database.
  2. Kamei S, Wakabayashi K, Shimazono M (1964). "Studies on ω-Oxidation of Fatty Acids in vitro: II. ω-Hydroxy Fatty Acid: NAD Oxidoreductase". J. Biochem. 56: 72–76. doi:10.1093/oxfordjournals.jbchem.a127961. PMID   14202238.
  3. Mitz MA; Henrikson RL (1961). "Omega hydroxy fatty acid dehydrogenase". Biochim. Biophys. Acta. 46: 45–50. doi:10.1016/0006-3002(61)90644-8. PMID   13771448.