Postarthroscopic glenohumeral chondrolysis

Postarthroscopic glenohumeral chondrolysis
Postarthroscopic glenohumeral chondrolysis
	Human shoulder (joint)
Specialty	Orthopedic
Risk factors	Complication of arthroscopic surgery

Last updated October 04, 2025

Postarthroscopic glenohumeral chondrolysis (PAGCL) is a rare complication of arthroscopic surgery and involves chondrolysis wherein the articular cartilage of the shoulder undergoes rapid, degenerative changes shortly after arthroscopic surgery.^[1]

Signs and symptoms

Causes

Bupivacaine, lidocaine, ropivacaine and levobupivacaine are all toxic to cartilage and their intra-articular infusions can lead to this toxic effect.^[2] Intra-articular pain pumps with local anesthetics have been implicated as a potential cause.^[3]

Diagnosis

Treatment

Total Joint Arthroplasty or reverse total joint arthroplasty (shoulder replacement surgery)^{[ citation needed ]}

References

↑ Yeh, PC; Kharrazi, FD (February 2012). "Postarthroscopic glenohumeral chondrolysis". The Journal of the American Academy of Orthopaedic Surgeons. 20 (2): 102–12. doi:10.5435/JAAOS-20-02-102. PMID 22302448. S2CID 11304366.
↑ Gulihar, Abhinav; Robati, Shibby; Twaij, Haider; Salih, Alan; Taylor, Grahame J.S. (December 2015). "Articular cartilage and local anaesthetic: A systematic review of the current literature". Journal of Orthopaedics. 12 (Suppl 2): S200 –S210. doi:10.1016/j.jor.2015.10.005. PMC 4796530 . PMID 27047224.
↑ Busfield, Benjamin T.; Romero, Denise M.; Korshad, Daniel; Kharrazi, F. Daniel (June 2014). "Subacromial pain pump use is safe after arthroscopic rotator cuff repair". Journal of Orthopaedics. 11 (2): 64–67. doi:10.1016/j.jor.2014.04.012. PMC 4118566 . PMID 25104887.

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[1] Yeh, PC; Kharrazi, FD (February 2012). "Postarthroscopic glenohumeral chondrolysis". The Journal of the American Academy of Orthopaedic Surgeons. 20 (2): 102–12. doi:10.5435/JAAOS-20-02-102. PMID 22302448. S2CID 11304366.

[pmid27047224-2] Gulihar, Abhinav; Robati, Shibby; Twaij, Haider; Salih, Alan; Taylor, Grahame J.S. (December 2015). "Articular cartilage and local anaesthetic: A systematic review of the current literature". Journal of Orthopaedics. 12 (Suppl 2): S200 –S210. doi:10.1016/j.jor.2015.10.005. PMC 4796530 . PMID 27047224.

[pmid25104887-3] Busfield, Benjamin T.; Romero, Denise M.; Korshad, Daniel; Kharrazi, F. Daniel (June 2014). "Subacromial pain pump use is safe after arthroscopic rotator cuff repair". Journal of Orthopaedics. 11 (2): 64–67. doi:10.1016/j.jor.2014.04.012. PMC 4118566 . PMID 25104887.

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