Rete mirabile | |
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Identifiers | |
TA98 | A12.0.00.013 |
TA2 | 3928 |
FMA | 76728 |
Anatomical terminology |
A rete mirabile (Latin for "wonderful net"; pl.: retia mirabilia) is a complex of arteries and veins lying very close to each other, found in some vertebrates, mainly warm-blooded ones. The rete mirabile utilizes countercurrent blood flow within the net (blood flowing in opposite directions) to act as a countercurrent exchanger. It exchanges heat, ions, or gases between vessel walls so that the two bloodstreams within the rete maintain a gradient with respect to temperature, or concentration of gases or solutes. This term was coined by Galen. [1] [2]
The effectiveness of retia is primarily determined by how readily the heat, ions, or gases can be exchanged. For a given length, they are most effective with respect to gases or heat, then small ions, and decreasingly so with respect to other substances.[ citation needed ]
The retia can provide for extremely efficient exchanges. In bluefin tuna, for example, nearly all of the metabolic heat in the venous blood is transferred to the arterial blood, thus conserving muscle temperature; that heat exchange approaches 99% efficiency. [3] [4]
In birds with webbed feet, retia mirabilia in the legs and feet transfer heat from the outgoing (hot) blood in the arteries to the incoming (cold) blood in the veins. The effect of this biological heat exchanger is that the internal temperature of the feet is much closer to the ambient temperature, thus reducing heat loss. Penguins also have them in the flippers and nasal passages.
Seabirds distill seawater using countercurrent exchange in a so-called salt gland with a rete mirabile. The gland secretes highly concentrated brine stored near the nostrils above the beak. The bird then "sneezes" the brine out. As freshwater is not usually available in their environments, some seabirds, such as pelicans, petrels, albatrosses, gulls and terns, possess this gland, which allows them to drink the salty water from their environments while they are hundreds of miles away from land. [5] [6]
Fish have evolved retia mirabilia multiple times to raise the temperature [7] (endothermy) or the oxygen concentration of a body part above the ambient level. [8]
In many fish, a rete mirabile helps fill the swim bladder with oxygen, increasing the fish's buoyancy. The rete mirabile is an essential [8] part of the system that pumps dissolved oxygen from a low partial pressure () of 0.2 atmospheres into a gas filled bladder that is at a pressure of hundreds of atmospheres. [9] A rete mirabile called the choroid rete mirabile is found in most living teleosts and raises the of the retina. [8] The higher supply of oxygen allows the teleost retina to be thick and have few blood vessels thereby increasing its sensitivity to light. [10] In addition to raising the , the choroid rete has evolved to raise the temperature of the eye in some teleosts and sharks. [7]
A countercurrent exchange system is utilized between the venous and arterial capillaries. Lowering the pH levels in the venous capillaries causes oxygen to unbind from blood hemoglobin because of the Root effect. This causes an increase in venous blood oxygen partial pressure, allowing the oxygen to diffuse through the capillary membrane and into the arterial capillaries, where oxygen is still sequestered to hemoglobin. The cycle of diffusion continues until the partial pressure of oxygen in the arterial capillaries exceeds that in the swim bladder. At this point, the dissolved oxygen in the arterial capillaries diffuses into the swim bladder via the gas gland. [11]
The rete mirabile allows for an increase in muscle temperature in regions where this network of vein and arteries is found. The fish is able to thermoregulate certain areas of its body. Additionally, this increase in temperature leads to an increase in basal metabolic temperature. The fish is now able to split ATP at a higher rate and ultimately can swim faster.
The opah utilizes retia mirabilia to conserve heat, making it the newest addition to the list of regionally endothermic fish. Blood traveling through capillaries in the gills must carry cold blood due to their exposure to cold water, but retia mirabilia in the opah's gills are able to transfer heat from warm blood in arterioles coming from the heart that heats this colder blood in arterioles leaving the gills. The huge pectoral muscles of the opah, which generate most of the body heat, are thus able to control the temperature of the rest of the body. [12]
This section needs additional citations for verification .(February 2021) |
In mammals, an elegant rete mirabile in the efferent arterioles of juxtamedullary glomeruli is important in maintaining the hypertonicity of the renal medulla. It is the hypertonicity of this zone, resorbing water osmotically from the renal collecting ducts as they exit the kidney, that makes possible the excretion of a hypertonic urine and maximum conservation of body water.
Vascular retia mirabilia are also found in the limbs of a range of mammals. These reduce the temperature in the extremities. Some of these probably function to prevent heat loss in cold conditions by reducing the temperature gradient between the limb and the environment. Others reduce the temperature of the testes increasing their productivity. In the neck of the dog, a rete mirabile protects the brain when the body overheats during hunting; the venous blood is cooled down by panting before entering the net.
Retia mirabilia also occur frequently in mammals that burrow, dive or have arboreal lifestyles that involve clinging with the limbs for lengthy periods. In these cases, the rete mirabile may lower limb temperature and therefore the metabolic requirement for oxygen and nutrients in the tissues of the limb. This would be desirable when the blood supply to the limb is limited as a result of a "diving reflex" diverting blood away from the limbs during diving or burrowing or because of postural restrictions on blood supply in the case of clinging, arboreal animals. In the last case, slow-moving arboreal mammals such as sloths, lorises and arboreal anteaters possess retia of the highly developed type known as vascular bundles. The structure and function of these mammalian retia mirabilia are reviewed by O'Dea (1990). [13]
The ancient physician Galen mistakenly thought that humans also have a rete mirabile in the neck, apparently based on dissection of sheep and misidentifying the results with the human carotid sinus, and ascribed important properties to it; it fell to Berengario da Carpi first, and then to Vesalius to demonstrate the error.
An artery is a blood vessel in humans and most other animals that takes oxygenated blood away from the heart in the systemic circulation to one or more parts of the body. Exceptions that carry deoxygenated blood are the pulmonary arteries in the pulmonary circulation that carry blood to the lungs for oxygenation, and the umbilical arteries in the fetal circulation that carry deoxygenated blood to the placenta.
Blood vessels are the components of the circulatory system that transport blood throughout the human body. These vessels transport blood cells, nutrients, and oxygen to the tissues of the body. They also take waste and carbon dioxide away from the tissues. Blood vessels are needed to sustain life, because all of the body's tissues rely on their functionality.
The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels. The circulatory system has two divisions, a systemic circulation or circuit, and a pulmonary circulation or circuit. Some sources use the terms cardiovascular system and vascular system interchangeably with the circulatory system.
The respiratory system is a biological system consisting of specific organs and structures used for gas exchange in animals and plants. The anatomy and physiology that make this happen varies greatly, depending on the size of the organism, the environment in which it lives and its evolutionary history. In land animals the respiratory surface is internalized as linings of the lungs. Gas exchange in the lungs occurs in millions of small air sacs; in mammals and reptiles these are called alveoli, and in birds they are known as atria. These microscopic air sacs have a very rich blood supply, thus bringing the air into close contact with the blood. These air sacs communicate with the external environment via a system of airways, or hollow tubes, of which the largest is the trachea, which branches in the middle of the chest into the two main bronchi. These enter the lungs where they branch into progressively narrower secondary and tertiary bronchi that branch into numerous smaller tubes, the bronchioles. In birds, the bronchioles are termed parabronchi. It is the bronchioles, or parabronchi that generally open into the microscopic alveoli in mammals and atria in birds. Air has to be pumped from the environment into the alveoli or atria by the process of breathing which involves the muscles of respiration.
Countercurrent exchange is a mechanism occurring in nature and mimicked in industry and engineering, in which there is a crossover of some property, usually heat or some chemical, between two flowing bodies flowing in opposite directions to each other. The flowing bodies can be liquids, gases, or even solid powders, or any combination of those. For example, in a distillation column, the vapors bubble up through the downward flowing liquid while exchanging both heat and mass.
The swim bladder, gas bladder, fish maw, or air bladder is an internal gas-filled organ that contributes to the ability of many bony fish to control their buoyancy, and thus to stay at their current water depth without having to expend energy in swimming. Also, the dorsal position of the swim bladder means the center of mass is below the center of volume, allowing it to act as a stabilizing agent. Additionally, the swim bladder functions as a resonating chamber, to produce or receive sound.
The nephron is the minute or microscopic structural and functional unit of the kidney. It is composed of a renal corpuscle and a renal tubule. The renal corpuscle consists of a tuft of capillaries called a glomerulus and a cup-shaped structure called Bowman's capsule. The renal tubule extends from the capsule. The capsule and tubule are connected and are composed of epithelial cells with a lumen. A healthy adult has 1 to 1.5 million nephrons in each kidney. Blood is filtered as it passes through three layers: the endothelial cells of the capillary wall, its basement membrane, and between the foot processes of the podocytes of the lining of the capsule. The tubule has adjacent peritubular capillaries that run between the descending and ascending portions of the tubule. As the fluid from the capsule flows down into the tubule, it is processed by the epithelial cells lining the tubule: water is reabsorbed and substances are exchanged ; first with the interstitial fluid outside the tubules, and then into the plasma in the adjacent peritubular capillaries through the endothelial cells lining that capillary. This process regulates the volume of body fluid as well as levels of many body substances. At the end of the tubule, the remaining fluid—urine—exits: it is composed of water, metabolic waste, and toxins.
Gas exchange is the physical process by which gases move passively by diffusion across a surface. For example, this surface might be the air/water interface of a water body, the surface of a gas bubble in a liquid, a gas-permeable membrane, or a biological membrane that forms the boundary between an organism and its extracellular environment.
The microcirculation is the circulation of the blood in the smallest blood vessels, the microvessels of the microvasculature present within organ tissues. The microvessels include terminal arterioles, metarterioles, capillaries, and venules. Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins.
Opahs, also commonly known as moonfish, sunfish, kingfish, and redfin ocean pan are large, colorful, deep-bodied pelagic lampriform fishes comprising the small family Lampridae.
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The American flamingo is a large species of flamingo native to the West Indies, northern South America and the Yucatan Peninsula. It is closely related to the greater flamingo and Chilean flamingo, and was formerly considered conspecific with the greater flamingo, but that treatment is now widely viewed as incorrect due to a lack of evidence. It is also known as the Caribbean flamingo, although it is also present in the Galápagos Islands. It is the only flamingo that naturally inhabits North America.
The vasa recta of the kidney, are the straight arterioles, and the straight venules of the kidney, – a series of blood vessels in the blood supply of the kidney that enter the medulla as the straight arterioles, and leave the medulla to ascend to the cortex as the straight venules.. They lie parallel to the loop of Henle.
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The southern bluefin tuna is a tuna of the family Scombridae found in open southern Hemisphere waters of all the world's oceans mainly between 30°S and 50°S, to nearly 60°S. At up to 2.5 metres and weighing up to 260 kilograms (570 lb), it is among the larger bony fishes.
A pulmonary shunt is the passage of deoxygenated blood from the right side of the heart to the left without participation in gas exchange in the pulmonary capillaries. It is a pathological condition that results when the alveoli of parts of the lungs are perfused with blood as normal, but ventilation fails to supply the perfused region. In other words, the ventilation/perfusion ratio of those areas is zero.
The Root effect is a physiological phenomenon that occurs in fish hemoglobin, named after its discoverer R. W. Root. It is the phenomenon where an increased proton or carbon dioxide concentration (lower pH) lowers hemoglobin's affinity and carrying capacity for oxygen. The Root effect is to be distinguished from the Bohr effect where only the affinity to oxygen is reduced. Hemoglobins showing the Root effect show a loss of cooperativity at low pH. This results in the Hb-O2 dissociation curve being shifted downward and not just to the right. At low pH, hemoglobins showing the Root effect don't become fully oxygenated even at oxygen tensions up to 20kPa. This effect allows hemoglobin in fish with swim bladders to unload oxygen into the swim bladder against a high oxygen gradient. The effect is also noted in the choroid rete, the network of blood vessels which carries oxygen to the retina. In the absence of the Root effect, retia will result in the diffusion of some oxygen directly from the arterial blood to the venous blood, making such systems less effective for the concentration of oxygen. It has also been hypothesized that the loss of affinity is used to provide more oxygen to red muscle during acidotic stress.
Lampris guttatus, commonly known as the opah, cravo, moonfish, kingfish, and Jerusalem haddock, is a large, colorful, deep-bodied pelagic lampriform fish belonging to the family Lampridae, which comprises the genus Lampris.
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