Sulcatone reductase

sulcatone reductase
Identifiers
EC no.	1.1.1.260
CAS no.	196522-54-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, sulcatone reductase (EC 1.1.1.260) is an enzyme that catalyzes the chemical reaction

sulcatol

+ NAD⁺

 

 

 

H⁺

 

H⁺

 

sulcatone

+ NADH

 

The two substrates of this enzyme are sulcatol and oxidised nicotinamide adenine dinucleotide (NAD⁺). Its products are sulcatone, reduced NADH, and a proton. ^{[1] [2] [3] [4]}

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is sulcatol:NAD⁺ oxidoreductase.

References

1. Enzyme 1.1.1.260 at KEGG Pathway Database.
2. Belan A, Botle J, Fauve A, Gourcy JG, Veschambre H (1987). "Use of biological systems for the preparation of chiral molecules 3. An application in pheromone synthesis: Preparation of sulcatol enantiomers". J. Org. Chem. 52 (2): 256–260. doi:10.1021/jo00378a017.
3. Tidswell EC, Salter GJ, Kell DB, Morris JG (1997). "Enantioselectivity of sulcatone reduction by some anaerobic bacteria". Enzyme and Microbial Technology. 21 (2): 143–147. doi:10.1016/S0141-0229(96)00264-5.
4. Tidswell EC, Thompson AN, Morris JG (1991). "Selection in chemostat culture of a mutant strain of Clostridium tryobutyricum improved in its reduction of ketones". J. Appl. Microbiol. Biotechnol. 35 (3): 317–322. doi:10.1007/BF00172719. PMID   22622932.