The 1959 Isle of Man TT, the second round of the 1959 Grand Prix motorcycle racing season, involved races on both the Mountain Course and the Clypse Course on the Isle of Man. John Surtees won the Senior race with a time of 3:00.13.4, adding to his earlier victory in the Junior race. Tarquinio Provini won both the Lightweight and Ultra-Lightweight categories, while Walter Schneider and H.Strauss won the sidecar event.
7 Laps (264.11 Miles) Mountain Course.
| Place | Rider | Number | Country | Machine | Speed | Time | Points |
|---|---|---|---|---|---|---|---|
| 1 |  John Surtees | Britain | MV Agusta | 95.38 mph | 2:46.08.0 | 8 | |
| 2 | John Hartle | Britain | MV Agusta | 93.65 mph | 2:49.12.2 | 6 | |
| 3 | Alistair King | Britain | Norton | 93.56 mph | 2:49.22.6 | 4 | |
| 4 | Geoff Duke | Britain | Norton | 93.10 mph | 2:50.12.4 | 3 | |
| 5 | Bob Anderson | Britain | Norton | 92.67 mph | 2:50.59.6 | 2 | |
| 6 | Dave Chadwick | Britain | Norton | 92.51 mph | 2:51.17.6 | 1 |
10 Laps (107.90 miles) Clypse Course.
| Place | Rider | Number | Country | Machine | Speed | Time | Points |
|---|---|---|---|---|---|---|---|
| 1 |  Tarquinio Provini | Italy | MV Agusta | 77.77 mph | 1:23.15.8 | 8 | |
| 2 | Carlo Ubbiali | Italy | MV Agusta | 77.76 mph | 1:23.16.2 | 6 | |
| 3 | Dave Chadwick | Britain | MV Agusta | 74.52 mph | 1:26.52.4 | 4 | |
| 4 | Tommy Robb | Britain | GMS | 73.60 mph | 1:27.57.0 | 3 | |
| 5 |  Horst Kassner | Germany | NSU | 72.18 mph | 1:29.43.0 | 2 | |
| 6 |  Rudi Thalhammer | Austria | NSU | 72.07 mph | 1:29.49.6 | 1 |
10 Laps (107.90 miles) Clypse Course.
| Place | Rider | Number | Country | Machine | Speed | Time | Points |
|---|---|---|---|---|---|---|---|
| 1 | Tarquinio Provini | Italy | MV Agusta | 74.06 mph | 1:27.52.2 | 8 | |
| 2 |  Luigi Taveri | Switzerland | MZ | 73.95 mph | 1:27.32.6 | 6 | |
| 3 | Mike Hailwood | Britain | Ducati | 72.15 mph | 1:29.44.0 | 4 | |
| 4 |  Horst Fügner | Germany | MZ | 71.91 mph | 1:30.11.6 | 3 | |
| 5 | Carlo Ubbiali | Italy | MV Agusta | 71.20 mph | 1:30.56.6 | 2 | |
| 6 |  Naomi Taniguchi | Japan | Honda | 68.29 mph | 1:34.48.0 | 1 |
10 Laps (107.90 miles) Clypse Course.
| Place | Rider | Number | Country | Machine | Speed | Time | Points |
|---|---|---|---|---|---|---|---|
| 1 | Walter Schneider/H.Strauss | 3 | Germany | BMW | 72.69 mph | 1:29.03.8 | 8 |
| 2 | Florian Camathias/H.Cecco | 9 | Switzerland | BMW | 71.05 mph | 1:31.06.8 | 6 |
| 3 | Fritz Scheidegger/H.Burkhardt | 25 | Switzerland | BMW | 69.42 mph | 1:33.16.2 | 4 |
| 4 | Helmut Fath/A.Wohlgemuth | 5 | Germany | BMW | 68.95 mph | 1:33.51.0 | 3 |
| 5 | Edgar Strub/R Mick Woolett | 17 | Germany | BMW | 67.31 mph | 1:36.12.2 | 2 |
| 6 | Owen Greenwood/Terry Fairbrother | 28 | Britain | Norton | 66.56 mph | 1:37.15.8 | 1 |
7 Laps (274.11 Miles) Mountain Course.
| Place | Rider | Number | Country | Machine | Speed | Time | Points |
|---|---|---|---|---|---|---|---|
| 1 | John Surtees | Britain | MV Agusta | 87.94 mph | 3:00.13.4 | 8 | |
| 2 | Alistair King | Britain | Norton | 85.50 mph | 3:05.21.0 | 6 | |
| 3 |  Bob Brown | Australia | Norton | 83.00 mph | 3:10.56.4 | 4 | |
| 4 | Derek T.Powell | Britain | Matchless | 82.87 mph | 3:11.14.2 | 3 | |
| 5 | Bob McIntyre | Britain | Norton | 82.34 mph | 3:12.27.8 | 2 | |
| 6 |  Paddy Driver | South Africa | Norton | 81.34 mph | 3:14.55.4 | 1 |