Cytidylate cyclase

cytidylate cyclase
Identifiers
EC no.	4.6.1.6
CAS no.	65357-82-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The enzyme cytidylate cyclase (EC 4.6.1.6) is an enzyme that catalyzes the reaction

CTP = 3′,5′-cyclic CMP + diphosphate

This enzyme belongs to the family of lyases, specifically the class of phosphorus-oxygen lyases. The systematic name of this enzyme class is CTP diphosphate-lyase (cyclizing; 3′,5′-cyclic-CMP-forming). Other names in common use include 3',5'-cyclic-CMP synthase, cytidylyl cyclase, cytidyl cyclase, and CTP diphosphate-lyase (cyclizing).

References

• Cech SY, Ignarro LJ (1978). "Cytidine 3',5'-monophosphate (cyclic CMP) formation by homogenates of mouse liver". Biochem. Biophys. Res. Commun. 80 (1): 119–25. doi:10.1016/0006-291X(78)91112-9. PMID   23778.
• Newton RP, Salih SG, Hakeem NA, Kingston EE, Beynon JH (1985). "3',5'-Cyclic UMP, -cyclic IMP, -cyclic TMP and related enzymes in mammalian-tissues". Biochem. Soc. Trans. 13: 1134–1135. doi:10.1042/bst0131134.