ADCY6

Last updated
ADCY6
Protein ADCY6 PDB 1azs.png
Identifiers
Aliases ADCY6 , AC6, LCCS8, adenylate cyclase 6
External IDs OMIM: 600294; MGI: 87917; HomoloGene: 22400; GeneCards: ADCY6; OMA:ADCY6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015270
NM_020983
NM_001390830
NM_001390831

NM_007405
NM_001368413

RefSeq (protein)

NP_056085

NP_031431
NP_001355342

Location (UCSC) Chr 12: 48.77 – 48.79 Mb Chr 15: 98.49 – 98.51 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Adenylyl cyclase type 6 is an enzyme that in humans is encoded by the ADCY6 gene. [5]

Contents

Function

This gene encodes adenylyl cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants. [5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000174233 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022994 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: ADCY6 adenylate cyclase 6".

Further reading