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In scientific inquiry and academic research, data fabrication is the intentional misrepresentation of research results. As with other forms of scientific misconduct, it is the intent to deceive that marks fabrication as unethical, and thus different from scientists deceiving themselves. There are many ways data can be fabricated. Experimental data can be fabricated by reporting experiments that were never conducted, and accurate data can be manipulated or misrepresented to suit a desired outcome. One of the biggest problems with this form of scientific fraud is that "university investigations into research misconduct are often inadequate, opaque and poorly conducted. They challenge the idea that institutions can police themselves on research integrity." [1]
Sometimes intentional fabrication can be difficult to distinguish from unintentional academic incompetence or malpractice. Examples of this include the failure to account for measurement error, or the failure to adequately control experiments for any parameters being measured.
Fabrication can also occur in the context of undergraduate or graduate studies wherein a student fabricates a laboratory or homework assignment. Such cheating, when discovered, is usually handled within the institution, and does not become a scandal within the larger academic community (as cheating by students seldom has any academic significance).
A finding that a scientist engaged in fabrication will often mean the end to their career as a researcher. Scientific misconduct is grounds for dismissal of tenured faculty, as well as for forfeiture of research grants. Given the tight-knit nature of many academic communities, and the high stakes involved, researchers who are found to have committed fabrication are often effectively (and permanently) blacklisted from the profession, with reputable research organizations and universities refusing to hire them; funding sources refusing to sponsor them or their work, and journals refusing to consider any of their articles for publication. In some cases, however, especially if the researcher is senior and well-established, the academic community can close ranks to prevent injury to the scientist's career. [2]
Fabricators may also have previously earned academic credentials removed. Two cases:
Not all alleged fraud is found to be so, and debates are part of the scientific community. An interesting case is the accusation against Dr. Margaret Mead, a world-renowned anthropologist who published field work conducted early in her life, which proclaimed that Samoan culture was more relaxed and harmonious about sexual relations and mores. Her truthfulness and research process were roundly criticized by a later researcher in Samoa, Dr. Derek Freeman. More recently, Dr. Freeman's own research quality has come under scrutiny, with a hint that perhaps his own views on sexuality and his research with Elders in Samoa led him to reject Dr. Mead's findings. Dr. Freeman's allegations harmed Dr. Mead's reputation at a time when few women were scientists [6]
Scientific misconduct is the violation of the standard codes of scholarly conduct and ethical behavior in the publication of professional scientific research.
The Schön scandal concerns German physicist Jan Hendrik Schön who briefly rose to prominence after a series of apparent breakthroughs with semiconductors that were later discovered to be fraudulent. Before he was exposed, Schön had received the Otto-Klung-Weberbank Prize for Physics and the Braunschweig Prize in 2001, as well as the Outstanding Young Investigator Award of the Materials Research Society in 2002, all of which were later rescinded.
In academic publishing, a retraction is a mechanism by which a published paper in an academic journal is flagged for being seriously flawed to the extent that their results and conclusions can no longer be relied upon. Retracted articles are not removed from the published literature but marked as retracted. In some cases it may be necessary to remove an article from publication, such as when the article is clearly defamatory, violates personal privacy, is the subject of a court order, or might pose a serious health risk to the general public.
Coming of Age in Samoa: A Psychological Study of Primitive Youth for Western Civilisation is a 1928 book by American anthropologist Margaret Mead based upon her research and study of youth – primarily adolescent girls – on the island of Taʻū in the Samoan Islands. The book details the sexual life of teenagers in Samoan society in the early 20th century, and theorizes that culture has a leading influence on psychosexual development.
John Roland Darsee is an American physician and former medical researcher. After compiling an impressive list of publications in reputable scientific journals, he was found to have fabricated data for his publications.
Luk Van Parijs was an associate professor of biology at the Massachusetts Institute of Technology (MIT) Center for Cancer Research. After investigating for a year, MIT fired Van Parijs for research misconduct. Van Parijs admitted to fabricating and falsifying research data in a paper, several unpublished manuscripts, and grant applications. In March 2011, Van Parijs pleaded guilty in a U.S. District Court in Boston to one count of making a false statement on a federal grant application. The government asked Judge Denise Casper for a 6-month jail term because of the seriousness of the fraud, which involved a $2-million grant. After several prominent scientists including Van Parijs' former post-doc supervisor pleading for clemency on his behalf, on 13 June, Van Parijs was finally sentenced six months of home detention with electronic monitoring, plus 400 hours of community service and a payment to MIT of $61,117 - restitution for the already-spent grant money that MIT had to return to the National Institutes of Health.
Thereza Imanishi-Kari is an associate professor of pathology at Tufts University. Her research focuses on the origins of autoimmune diseases, particularly systemic lupus erythematosus, studied using mice as model organisms. Previously she had been a faculty member at the Massachusetts Institute of Technology. She is notable for her role in what became known as the "Baltimore affair", in which a 1986 paper she co-authored with David Baltimore was the subject of research misconduct allegations. Following a series of investigations, she was fully exonerated of the charges in 1996.
Jon Sudbø is a Norwegian dentist, physician, and former medical researcher, who was exposed as a scientific fraudster in 2006. Over a period of several years, he fabricated results in the field of oncology which he published in leading medical journals. The article that led to his downfall, which was published in The Lancet, was based on 900 patients Sudbø had fabricated entirely. The editor of The Lancet described this as the biggest scientific fraud conducted by a single researcher ever.
Ranjit Kumar Chandra is an Indian-born Canadian researcher and self-proclaimed "father of nutritional immunology" who committed scientific and health care fraud. Chandra's misconduct was the subject of a 2006 documentary by the Canadian Broadcasting Corporation (CBC). A libel trial in July 2015, concluded that the allegations of fraud against Chandra were truthful; he was ordered to pay $1.6 million to cover CBC's legal fees, and later that year was stripped of his membership in the Order of Canada. As of 2020, four of Chandra's research publications have been retracted, and one has been corrected.
Marc D. Hauser is an American evolutionary biologist and a researcher in primate behavior, animal cognition and human behavior and neuroscience. Hauser was a professor of psychology at Harvard University from 1998 to 2011. In 2010 Harvard found him guilty of research misconduct, specifically fabricating and falsifying data, after which he resigned. Because Hauser's research was financed by government grants, the Office of Research Integrity of the Health and Human Services Department also investigated, finding in 2012 that Hauser had fabricated data, manipulated experimental results, and published falsified findings.
Academic authorship of journal articles, books, and other original works is a means by which academics communicate the results of their scholarly work, establish priority for their discoveries, and build their reputation among their peers.
Scott S. Reuben is an American anesthesiologist who falsified data heralding the benefits of the Pfizer pain medication Celebrex while downplaying its negative side effects.
Dipak Kumar Das was the director of the Cardiovascular Research Center at the University of Connecticut Health Center in Farmington and is known for research fraud. His work centered on the beneficial properties of resveratrol, which is found in red wine, but over twenty of his research papers have been since retracted.
Yoshitaka Fujii is a Japanese researcher in anesthesiology, who in 2012 was found to have fabricated data in at least 219 scientific papers, setting what is believed to be a record for the number of papers by a single author requiring retractions.
H.M. Krishna Murthy is a former researcher from the University of Alabama at Birmingham. In 2009, several of his publications were retracted from scientific journals after accusations of scientific misconduct surfaced. UAB began investigating claims of fraud in January 2007 after the validity of the proteins came into question. The University's probe produced ten publications that were shown not to be valid. These publications have since been retracted from their respective journals. Murthy's publications dealt with the crystal structures of several proteins that he had claimed to have determined using crystallographic methods. It was found that these protein structures were never properly determined and the primary crystallographic data for at least some of them have been fabricated by Murthy.
Haruko Obokata is a former stem-cell biologist and research unit leader at Japan's Laboratory for Cellular Reprogramming, Riken Center for Developmental Biology. She claimed in 2014 to have developed a radical and remarkably easy way to generate stimulus-triggered acquisition of pluripotency (STAP) cells that could be grown into tissue for use anywhere in the body. In response to allegations of irregularities in Obokata's research publications involving STAP cells, Riken launched an investigation that discovered examples of scientific misconduct on the part of Obokata. Attempts to replicate Obokata's STAP cell results failed. The ensuing STAP cell scandal gained worldwide attention.
Jonathan Neal Pruitt is a former academic researcher. He was an Associate Professor of behavioral ecology and Canada 150 Research Chair in Biological Dystopias at McMaster University. Pruitt's research focused primarily on animal personalities and the social behavior of spiders and other organisms.
Sophie Jamal is a Canadian endocrinologist and former osteoporosis researcher who was at the centre of a scientific misconduct case in the mid-to-late 2010s. Jamal published a high-profile paper suggesting that the heart medication nitroglycerin was a treatment for osteoporosis, and was later demonstrated to have misrepresented her results. She received a lifetime ban from receiving funding from the Canadian Institutes of Health Research and was named directly in their disclosure report, becoming the first person mentioned by name by the institute for scientific misconduct. Jamal was later stripped of her medical license for two years, regaining it in a controversial 3–2 decision.