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International Medical Corps is a global, nonprofit, humanitarian aid organization that provides emergency medical services, healthcare training and capacity building to those affected by disaster, disease or conflict." It seeks to strengthen medical services and infrastructure in the aftermath of crises."
Natural News is a far-right, anti-vaccination conspiracy theory and fake news website known for promoting alternative medicine, pseudoscience, disinformation, and far-right extremism. The website began publishing articles in 2008 and is based in the United States.
Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after infection. The first symptoms are usually fever, sore throat, muscle pain, and headaches. These are usually followed by vomiting, diarrhoea, rash and decreased liver and kidney function, at which point some people begin to bleed both internally and externally. It kills between 25% and 90% of those infected – about 50% on average. Death is often due to shock from fluid loss, and typically occurs between six and 16 days after the first symptoms appear. Early treatment of symptoms increases the survival rate considerably compared to late start. An Ebola vaccine was approved by the US FDA in December 2019.
Brincidofovir, sold under the brand name Tembexa, is an antiviral drug used to treat smallpox. Brincidofovir is a prodrug of cidofovir. Conjugated to a lipid, the compound is designed to release cidofovir intracellularly, allowing for higher intracellular and lower plasma concentrations of cidofovir, effectively increasing its activity against dsDNA viruses, as well as oral bioavailability.
The 2013–2016 epidemic of Ebola virus disease, centered in Western Africa, was the most widespread outbreak of the disease in history. It caused major loss of life and socioeconomic disruption in the region, mainly in Guinea, Liberia and Sierra Leone. The first cases were recorded in Guinea in December 2013; later, the disease spread to neighbouring Liberia and Sierra Leone, with minor outbreaks occurring in Nigeria and Mali. Secondary infections of medical workers occurred in the United States and Spain. In addition, isolated cases were recorded in Senegal, the United Kingdom and Italy. The number of cases peaked in October 2014 and then began to decline gradually, following the commitment of substantial international resources.
ZMapp is an experimental biopharmaceutical drug comprising three chimeric monoclonal antibodies under development as a treatment for Ebola virus disease. Two of the three components were originally developed at the Public Health Agency of Canada's National Microbiology Laboratory (NML), and the third at the U.S. Army Medical Research Institute of Infectious Diseases; the cocktail was optimized by Gary Kobinger, a research scientist at the NML and underwent further development under license by Mapp Biopharmaceutical. ZMapp was first used on humans during the Western African Ebola virus epidemic, having only been previously tested on animals and not yet subjected to a randomized controlled trial. The National Institutes of Health (NIH) ran a clinical trial starting in January 2015 with subjects from Sierra Leone, Guinea, and Liberia aiming to enroll 200 people, but the epidemic waned and the trial closed early, leaving it too statistically underpowered to give a meaningful result about whether ZMapp worked.
An Ebola virus epidemic in Sierra Leone occurred in 2014, along with the neighbouring countries of Guinea and Liberia. At the time it was discovered, it was thought that Ebola virus was not endemic to Sierra Leone or to the West African region and that the epidemic represented the first time the virus was discovered there. However, US researchers pointed to lab samples used for Lassa fever testing to suggest that Ebola had been in Sierra Leone as early as 2006.
An epidemic of Ebola virus disease in Guinea from 2013 to 2016 represents the first ever outbreak of Ebola in a West African country. Previous outbreaks have been confined to several countries in Sub-Saharan Africa.
An epidemic of Ebola virus disease occurred in Liberia from 2014 to 2015, along with the neighbouring countries of Guinea and Sierra Leone. The first cases of virus were reported by late March 2014. The Ebola virus, a biosafety level four pathogen, is an RNA virus discovered in 1976.
Four laboratory-confirmed cases of Ebola virus disease occurred in the United States in 2014. Eleven cases were reported, including these four cases and seven cases medically evacuated from other countries. The first was reported in September 2014. Nine of the people contracted the disease outside the US and traveled into the country, either as regular airline passengers or as medical evacuees; of those nine, two died. Two people contracted Ebola in the United States. Both were nurses who treated an Ebola patient; both recovered.
Ebola vaccines are vaccines either approved or in development to prevent Ebola. As of 2022, there are only vaccines against the Zaire ebolavirus. The first vaccine to be approved in the United States was rVSV-ZEBOV in December 2019. It had been used extensively in the Kivu Ebola epidemic under a compassionate use protocol. During the early 21st century, several vaccine candidates displayed efficacy to protect nonhuman primates against lethal infection.
Organizations from around the world responded to the West African Ebola virus epidemic. In July 2014, the World Health Organization (WHO) convened an emergency meeting with health ministers from eleven countries and announced collaboration on a strategy to co-ordinate technical support to combat the epidemic. In August, they declared the outbreak an international public health emergency and published a roadmap to guide and coordinate the international response to the outbreak, aiming to stop ongoing Ebola transmission worldwide within 6–9 months. In September, the United Nations Security Council declared the Ebola virus outbreak in the West Africa subregion a "threat to international peace and security" and unanimously adopted a resolution urging UN member states to provide more resources to fight the outbreak; the WHO stated that the cost for combating the epidemic will be a minimum of $1 billion.
This article covers the timeline of the 2014 Ebola virus epidemic in West Africa and its outbreaks elsewhere. Flag icons denote the first announcements of confirmed cases by the respective nation-states, their first deaths, and their first secondary transmissions, as well as relevant sessions and announcements of agencies such as the World Health Organization (WHO), the U.S. Centers for Disease Control (CDC), and NGOs such as Doctors Without Borders; medical evacuations, visa restrictions, border closures, quarantines, court rulings, and possible cases of zoonosis are also included.
The following lists events that happened during 2014 in Sierra Leone.
The Ebola virus epidemic in West Africa has had a large effect on the culture of most of the West African countries. In most instances, the effect is a rather negative one as it has disrupted many Africans’ traditional norms and practices. For instance, many West African communities rely on traditional healers and witch doctors, who use herbal remedies, massage, chant and witchcraft to cure just about any ailment. Therefore, it is difficult for West Africans to adapt to foreign medical practices. Specifically, West African resistance to Western medicine is prominent in the region, which calls for severe distrust of Western and modern medical personnel and practices.(see Ebola conspiracies below.)
There is a cure for the Ebola virus disease that is currently approved for market the US government has inventory in the Strategic National Stockpile. For past and current Ebola epidemics, treatment has been primarily supportive in nature.
False information, including intentional disinformation and conspiracy theories, about the scale of the COVID-19 pandemic and the origin, prevention, diagnosis, and treatment of the disease has been spread through social media, text messaging, and mass media. False information has been propagated by celebrities, politicians, and other prominent public figures. Many countries have passed laws against "fake news", and thousands of people have been arrested for spreading COVID-19 misinformation. The spread of COVID-19 misinformation by governments has also been significant.
Atoltivimab/maftivimab/odesivimab, sold under the brand name Inmazeb, is a fixed-dose combination of three monoclonal antibodies for the treatment of Zaire ebolavirus. It contains atoltivimab, maftivimab, and odesivimab-ebgn and was developed by Regeneron Pharmaceuticals.
Ebola-chan is an Internet meme depicting a moe anthropomorphization of the Ebola virus and was popularized on 4chan. The first known image of Ebola-chan began on the Japanese social media site, Pixiv, in 2014. A few days after, it was posted 4chan's /pol/ thread, who began posting messages praising Ebola-chan. Soon after, 4chan users began spreading the meme to Nairaland, the largest online message board in Nigeria, accompanying images of Ebola-chan with racist messages and associated conspiracy theories. This included claims that Ebola was CIA-made and that white people were performing rituals for Ebola to spread. The meme's spread has been considered racist and has been attributed to increased mistrust between West Africans and medical professionals.
References
- 1 2 Silverman, Laura (23 October 2014). "FDA Cracks Down On Fake Ebola Cures Sold Online". NPR.org. Retrieved 1 November 2022.
- ↑ Young, Saundra (26 September 2014). "FDA warns companies about fake Ebola drugs". CNN. Retrieved 1 November 2022.
- ↑ Oyeyemi, Sunday Oluwafemi; Gabarron, Elia; Wynn, Rolf (14 October 2014). "Ebola, Twitter, and misinformation: a dangerous combination?". BMJ. 349: g6178. doi: 10.1136/bmj.g6178 . ISSN 1756-1833. PMID 25315514 . Retrieved 1 November 2022.
- ↑ Silverman, Laura (20 October 2014). "Watch Out: Fake Ebola Treatments Are Spreading". KERA News. Retrieved 1 November 2022.
- 1 2 Healy, Melissa (3 October 2014). "Unproven Ebola cures, preventives proliferate". Los Angeles Times. Retrieved 1 November 2022.
- 1 2 Feuer, Alan (18 October 2014). "The Ebola Conspiracy Theories". The New York Times. Retrieved 27 October 2022.
- ↑ Joselow, Gabe; Givetash, Linda (20 April 2019). "Conspiracy theories, rumors threaten the battle against Ebola". NBC News. Retrieved 27 October 2022.
- ↑ "How This Pastor of a Megachurch Is Fueling Ebola Conspiracy Theories". Time. Retrieved 27 October 2022.
- ↑ Ouattara, Syna; Århem, Nikolas (January 2021). "Fighting Ebola in the Shadow of Conspiracy Theories and Sorcery Suspicions. Reflections on the West African EVD Outbreak in Guinea-Conakry (2013–2016)". African Studies Notebooks. doi:10.4000/etudesafricaines.33151 . Retrieved 27 October 2022.