 | It has been suggested that this article be merged with Insulin-degrading enzyme . (Discuss) Proposed since July 2025. |
| Insulysin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.24.56 | ||||||||
| CAS no. | 9013-83-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Insulysin (EC 3.4.24.56) (Also called insulinase, insulin-degrading enzyme , insulin protease, insulin proteinase, insulin-degrading neutral proteinase, insulin-specific protease, insulin-glucagon protease, metalloinsulinase, IDE) is an enzyme. [1] [2] [3] [4] [5] This enzyme catalyses the degradation reaction of insulin, glucagon and other polypeptides.
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This cytosolic enzyme is present in mammals and in many arthropods such as the fly Drosophila melanogaster .
