Intraretinal microvascular abnormalities

Intraretinal microvascular abnormalities
Human eye cross-sectional/ retina view
Specialty	Ophthalmology

Intraretinal microvascular abnormalities (IRMA) are abnormalities of the blood vessels that supply the retina of the eye, a sign of diabetic retinopathy. ^[1] IRMA can be difficult to distinguish from and is likely a precursor to retinal neovascularization. One way to distinguish IRMA from retinal neovascularization is to perform fluorescein angiography. Since IRMA blood vessels are patent, unlike neovascular vessels, they do not leak, and therefore exhibit hyperfluorescence on fluorescein angiography.^{[ citation needed ]}

IRMA is deeper in the retina than neovascularization, has blurrier edges, is more of a burgundy than a red, does not appear on the optic disc, and is usually seen after a shorter period of poorly controlled diabetes than neovascularization.^{[ citation needed ]}

References

1. Shimouchi, Akito; Ishibazawa, Akihiro; Ishiko, Satoshi; Omae, Tsuneaki; Ro-Mase, Tomoko; Yanagi, Yasuo; Yoshida, Akitoshi (9 March 2020). "A Proposed Classification of Intraretinal Microvascular Abnormalities in Diabetic Retinopathy Following Panretinal Photocoagulation". Investigative Ophthalmology & Visual Science. 61 (3): 34. doi:10.1167/iovs.61.3.34. ISSN   1552-5783. PMC   7401423 . PMID   32191287 . Retrieved 12 September 2022.

Further reading

• Sorour, Osama A.; Mehta, Nihaal; Baumal, Caroline R.; Ishibazawa, Akihiro; Liu, Keke; Konstantinou, Eleni K.; Martin, Sarah; Braun, Phillip; Alibhai, A. Yasin; Arya, Malvika; Witkin, Andre J.; Duker, Jay S.; Waheed, Nadia K. (2020). "Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography". Eye and Vision. 7 (1): 29. doi: 10.1186/s40662-020-00195-2 . ISSN   2326-0254. PMC   7262762 . PMID   32514410.
• Shimouchi, Akito; Ishibazawa, Akihiro; Ishiko, Satoshi; Omae, Tsuneaki; Ro-Mase, Tomoko; Yanagi, Yasuo; Yoshida, Akitoshi (March 19, 2020). "A Proposed Classification of Intraretinal Microvascular Abnormalities in Diabetic Retinopathy Following Panretinal Photocoagulation". Investigative Ophthalmology & Visual Science. 61 (3). Association for Research in Vision and Ophthalmology (ARVO): 34. doi:10.1167/iovs.61.3.34. ISSN   1552-5783. PMC   7401423 . PMID   32191287.